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Dutasteride + Tamsulosin

URINARY BLADDER RELAXANT

Uses of Dutasteride + Tamsulosin

  • Dutasteride + Tamsulosin are used to treat benign prostatic hyperplasia (BPH) in men with an enlarged prostate.

Side effects of Dutasteride + Tamsulosin

  • Problems with ejaculation
  • Dizziness
  • Low sexual desire
  • Impotence
  • Breast disorders or tenderness 

How Dutasteride + Tamsulosin works

  • Dutasteride is a 5-alpha-reductase inhibitor. It blocks the conversion of testosterone, a male sex hormone, into dihydrotestosterone (DHT). As the levels of DHT reduce in the body, the prostate gland shrinks, relieving the pressure it puts on the urethra and improving urinary symptoms.
  • Tamsulosin is an alpha-blocker. It works by relaxing the muscles in the prostate gland and the neck of the bladder. By relaxing muscles, it helps relieve the tightness and pressure on the urethra. It allows easy urine flow and alleviates urinary symptoms associated with BPH.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Dutasteride + Tamsulosin can be taken orally (tablet and capsule).

Age and Dose Restrictions

  • This combination can be used in adults above 18 years of age.

Contraindications

  • It is contraindicated in patients with a history of hypersensitivity to Dutasteride or Tamsulosin, or its combination. It is also contraindicated in pregnant women, breastfeeding women, children and women with childbearing potential.

Medications to Avoid with This Drug

  • Avoid taking other alpha-blockers, PDE5 inhibitors used to help achieve or maintain an erection (vardenafil, sildenafil citrate and tadalafil), antihypertensives (verapamil or diltiazem), HIV medications (ritonavir or indinavir), antifungals (itraconazole or ketoconazole), antidepressants (nefazodone or paroxetine), gastric acid reducers (cimetidine), anticoagulants (warfarin), antibiotics (erythromycin) and NSAIDs (diclofenac). These medications may alter the safety and effectiveness of Dutasteride + Tamsulosin.

Overdose and Missed Dose

  • Overdose can cause hypotension. Restoring blood pressure and heart rate can be done by making the patient lie down with the face upward. Strict adherence to the prescribed dose is essential to avoid hypotension.
  • If you miss a dose of Dutasteride + Tamsulosin, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management of Side Effects

  • The side effects of Dutasteride + Tamsulosin are usually temporary and resolve once the medication is discontinued. However, it is important to seek guidance from a doctor first before discontinuing the combination.

Use In Driving And Operating Machinery

  • This combination may cause dizziness and lightheadedness. Do not drive, operate machinery, or do other activities that require mental alertness or coordination until you know how this medication affects you. 

Caution in Other Conditions

  • Caution is advised in patients planning for cataract surgery, prostate cancer and patients with severe kidney or liver problems.

Special Dietary & Lifestyle Recommendation

  • Do not donate blood until 6 months after the last dose of this combination. 
  • Use protection during sexual intercourse as Dutasteride may affect the normal development of a male baby.
  • Don’t stop taking Dutasteride + Tamsulosin without talking to your doctor first.
  • Constipation can put extra strain on the bladder and worsen BPH symptoms. Adequate fibre intake promotes regular bowel movements, preventing constipation. Include fibre-rich foods like whole grains, legumes, fruits, and vegetables.
  • Take your time when urinating, ensuring you empty your bladder. Avoid straining and rushing during urination, which may contribute to urinary retention.

Frequently asked questions

Dutasteride + Tamsulosin may take several weeks to months to show noticeable improvements in Benign Prostatic Hyperplasia (BPH) symptoms. Individual responses vary, and consistent use is essential for optimal effectiveness.

No, Dutasteride + Tamsulosin typically does not affect blood sugar levels. 

Dutasteride + Tamsulosin is not habit-forming and is generally safe when used as directed.

Dutasteride + Tamsulosin usually requires a prescription and is unavailable over the counter.

Dutasteride + Tamsulosin can cause problems with erection and ejaculation, which may affect fertility in men. If you have concerns about fertility, it is recommended to consult with a doctor for personalised advice.

Dutasteride + Tamsulosin may cause a decrease in semen volume and semen concentration, but it does not completely stop the production of sperms. It is important to consult with a doctor for detailed information regarding the effects of Dutasteride and Tamsulosin on the production of sperm.

No, Dutasteride + Tamsulosin are not typically used to treat urinary tract infections (UTIs). It is primarily prescribed for managing benign prostatic hyperplasia (BPH) symptoms in men. 

Dutasteride + Tamsulosin are best when taken in the evening after a meal to avoid side effects. However, it is important to follow the specific dosing instructions provided by your doctor for optimal effectiveness.

Yes, Dutasteride + Tamsulosin can lower blood pressure levels. It is important to monitor blood pressure regularly while taking this medication and consult a doctor for personalised advice.

Terms & Conditions


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