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Furazolidone + Metronidazole

Uses of Furazolidone + Metronidazole

  • Furazolidone + Metronidazole is primarily used to manage diarrhoea, dysentery, stomach and intestinal infections coupled with food poisoning. It belongs to the class of antibiotics known as nitrofuran antibacterial agent and nitroimidazole's.

Side effects of Furazolidone + Metronidazole

  • Nausea

  • Vomiting

  • Stomach upset

  • Diarrhoea or constipation

  • Headache

  • Dizziness

  • Dry mouth

  • Unpleasant metallic taste

How Furazolidone + Metronidazole works

  • Furazolidone is a nitrofuran antibacterial agent and monoamine oxidase inhibitor It works by interfering with the enzymes and proteins that bacteria need to survive in the human body. By doing this, it disrupts the formation of the bacterial cell wall, which leads to the bacterial cells breaking down and dying.

  • Metronidazole is another type of antibiotic known as nitroimidazole. It acts on the DNA of bacteria and parasites. This damages their DNA and kills these microorganisms.

Certified content

Written By

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Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Reviewed By

Dr. Michelle Frank
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Expert Advice

Dosage Forms Available

  • The combination of Furazolidone + Metronidazole is available for oral administration (tablets and suspensions).

Age and Dose Restrictions

  • This medicine is intended for use by adults and children.

Contraindications

  • Furazolidone + Metronidazole is contraindicated in patients with known allergies to either of these medicines. Patients with Cockayne syndrome, a rare genetic disorder, should not take this combination. It is also contraindicated in anyone who has consumed alcohol in the past three days or taken disulfiram in the past two weeks.

Other Medications to Avoid

  • This combination may interact with disulfiram (such as chloramphenicol), anticoagulants (like warfarin), certain HIV medications (such as protease inhibitors like ritonavir, lopinavir, and atazanavir), antimanic agents (like lithium), H2 antagonists (like cimetidine), barbiturates (such as phenobarbital), and anticonvulsants (like phenytoin).

Overdose and Missed Dose

  • An overdose of Furazolidone + Metronidazole may lead to severe nausea, vomiting, dizziness, and neurological symptoms. If an overdose is suspected, seek emergency medical attention immediately.

  • If a dose is missed, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.

  • Taking this medication with food can help minimise gastrointestinal side effects like nausea and vomiting.

  • Staying well-hydrated can help manage side effects like dry mouth.

Use in Driving and Operating Machinery

  • Furazolidone + Metronidazole may cause dizziness. If you feel dizzy or lightheaded after taking this medication, avoid driving or operating heavy machinery until you know how it affects you.

Use in Pregnancy and Lactation

  • Furazolidone + Metronidazole should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nursing mothers should discard breast milk during treatment and for 24-48 hours after the last dose to avoid exposing infants to the medication.

Caution in Other Conditions

  • Patients with liver disease, kidney disease, blood disorders, or neurological conditions should exercise caution when taking Furazolidone + Metronidazole.

Special Dietary and Lifestyle Recommendations

  • Stay well-hydrated and maintain a balanced diet to support overall health while taking this medicine.

  • Regularly monitor your health while taking this medication, particularly if you have a pre-existing liver or kidney condition.

Frequently asked questions

Some people may experience dizziness as a side effect which could potentially impact sleep. If you experience persistent sleep issues while taking this medicine, consult your doctor.

If you are planning to conceive or are facing fertility issues, it is advisable to discuss this with your doctor.

Yes, it is safe to take Furazolidone + Metronidazole daily as directed by your doctor. Do not self-medicate or alter the dosage without consulting your doctor.

The best time to take Furazolidone + Metronidazole is as directed by your doctor. The medication should be taken with food to minimise gastrointestinal side effects.

Furazolidone + Metronidazole is a prescription medicine. You should only use it under the guidance of a doctor who will determine the appropriate dosage and duration for your condition.

The duration of treatment with Furazolidone + Metronidazole depends on the specific infection being managed and individual patient factors. Your doctor will provide a recommended course length based on these considerations.

The time taken by Furazolidone + Metronidazole to show its effect may vary depending on the individual and the type and severity of infection being managed.

Terms & Conditions


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