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Human Chorionic Gonadotropin

Uses of Human Chorionic Gonadotropin

  • Human Chorionic Gonadotropin is most commonly used to manage infertility in women and stimulate testosterone production in men and boys. It belongs to the group of hormones.

  • Additionally, it can assist in the descent of undescended testicles into the scrotum in young boys.

Side effects of Human Chorionic Gonadotropin

  • Injection site pain and swelling

  • Headache

  • Fatigue

  • Irritability

  • Water retention

How Human Chorionic Gonadotropin works

  • Human Chorionic Gonadotropin (hCG) is a hormonal medication.
  • It mimics the functioning of naturally occurring luteinizing hormone (LH) in the body. In females, it triggers the release of a mature egg from the ovary and supports the corpus luteum, producing progesterone to prepare the womb for pregnancy. 
  • In males, it stimulates Leydig cells in the testis to produce testosterone, promoting masculine characteristics and sperm production, helping with successful conception in adults and normal sexual development in adolescents.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama Ahmed Dental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Human Chorionic Gonadotropin comes as a powder to reconstitute with Bacteriostatic (sterile) water (diluent) and is administered as an injection.

Age and Dose Restrictions

  • This medicine is intended for use in adults and children; however, the specific age at which this treatment can commence depends on the condition being addressed.

Contraindications

  • Human Chorionic Gonadotropin is contraindicated in patients with allergies to it or its ingredients, ovarian cysts or enlarged ovaries not related to PCOS, thyroid or adrenal disorders, ovarian or uterine cancer, undiagnosed vaginal bleeding, pituitary gland disorders, and precocious puberty.

Other Medications to Avoid

  • This medication may interact with gonadotropin-releasing hormone agonists/antagonists (such as Leuprolide and Cetrorelix), androgens (including testosterone), and anti-androgens (such as Flutamide).

Overdose and Missed Dose

  • An overdose of Human Chorionic Gonadotropin can lead to symptoms such as severe pelvic pain, swelling of the hands or legs, and weight gain. In this event, immediately consult a doctor.

  • If you miss a dose of Human Chorionic Gonadotropin, administer it as soon as you remember, unless it is almost time for your next scheduled dose. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience severe side effects or worsening symptoms, consult your doctor.

  • To manage injection site pain or swelling, apply a cold pack immediately after injection.

  • For mild nausea or fatigue, adjust the timing of your dose slightly; take it while resting at home rather than just before leaving for work.

Use in Driving and Operating Machinery

  • Human Chorionic Gonadotropin does not generally affect your ability to drive or operate machinery. However, should you feel unusually tired after receiving an injection, avoid these activities until better.

Use in Pregnancy and Lactation

  • The use of Human Chorionic Gonadotropin in pregnancy and lactation is typically only recommended under medical supervision. Consult a doctor before starting treatment if pregnant or breastfeeding.

Caution in Other Conditions

  • Caution should be exercised when using Human Chorionic Gonadotropin in individuals with asthma, migraines, heart disease, kidney disease, epilepsy, and cardiac conditions.

Special Dietary and Lifestyle Recommendations

  • Maintain a balanced diet rich in fruits, vegetables, lean proteins, and whole grains to support overall health during treatment with Human Chorionic Gonadotropin.

  • Regular moderate exercise can help manage weight and improve physical well-being but should be adjusted according to any physical symptoms experienced during treatment.

  • Ensure adequate hydration especially if experiencing mild side effects like nausea or fatigue.

  • Managing stress through relaxation techniques such as yoga or meditation can be beneficial in coping with the emotional swings sometimes caused by hormonal treatments.

Frequently asked questions

Yes. It is produced naturally during pregnancy and, as a medication, is used to manage certain conditions in women and men.

Yes. Individuals with a history of depression are advised to consult their doctor before starting this medication as it may require close monitoring.

Yes. It stimulates the testis to produce testosterone and sperm, which can help treat hypogonadism and delayed puberty.

No such specific dietary restrictions are mentioned in provided references. However, it is advisable to discuss with your doctor about related concerns.

The frequency of administering Human Chorionic Gonadotropin depends on the condition being managed and your doctor's advice.

In women, ovulation usually occurs 24-48 hours after an injection, and in men, testosterone levels start to rise within 2-3 days of starting treatment.

Yes, you will need a prescription from your doctor. The medicine is not available over the counter.

Terms & Conditions

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