Sifasi Aqua 5000 Iu Injection 1 Ml

Sifasi Aqua 5000 Injection 1ml

Serum Institute Of India Ltd

Vial of 1 ML

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MRP ~~₹438.3~~

₹359.41

₹438.30/ML

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Composition

Human Chorionic Gonadotropin (5000 Iu)

Sifasi Aqua 5000 Injection is primarily used to manage infertility conditions in women and certain conditions in men. This medication belongs to a class of medicines known as hormones.

It is also used to stimulate the final maturation of follicles and trigger ovulation in women undergoing assisted reproductive techniques like in-vitro fertilisation. In men, it can be used to manage conditions such as undescended testes in pre-pubertal boys and hypogonadotropic hypogonadism.

Before using this medication, make sure to inform your doctor about any pre-existing health condition that may interfere with the treatment and increase complications.

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Sifasi Aqua 5000 Injection is used for the following:

Inducing ovulation in infertile women undergoing assisted reproductive techniques
Managing infertility in women with polycystic ovary syndrome who have received pre-treatment with follicle-stimulating hormone
Supporting the early stages of pregnancy in women undergoing in-vitro fertilisation
Treating undescended testes in adolescent boys
Stimulating testosterone production and prompting puberty in boys with delayed puberty due to pituitary deficiency
Managing male infertility by promoting sperm production.

Directions for Use of Sifasi Aqua 5000 Injection 1ml

Administer Sifasi Aqua 5000 Injection as follows:

The injection should be administered intramuscularly by a doctor.
The medicine needs to be mixed with the provided diluent before use.
Ensure the injection site is clean and sterile before administration.

Sifasi Aqua 5000 Injection is administered via an intramuscular route.

Side Effects of Sifasi Aqua 5000 Injection 1ml

Sifasi Aqua 5000 Injection may have the following common side effects:

Pain, redness and swelling at the injection site
Headache
Fatigue
Mood changes such as irritability
Nausea and vomiting
Abdominal pain: This could mean discomfort in your stomach area.
Breast tenderness or enlargement in men: This condition, known as gynecomastia, refers to swelling of the breast tissue.
Ovarian enlargement and abdominal distension in women: Your ovaries may become larger and your belly might swell due to fluid accumulation.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Sifasi Aqua 5000 Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea and Vomiting: Try to have a small meal before the injection, it might help reduce these symptoms.
Abdominal Pain: Lying down and resting after administration might help manage this discomfort.

How Sifasi Aqua 5000 Injection 1ml Works?

Sifasi Aqua 5000 Injection contains Chorionic Gonadotropin (5000 IU), which affects the body as follows:

Mimics Luteinising Hormone: Chorionic Gonadotropin is similar to luteinising hormone (LH) in structure and function, essentially acting as a substitute for LH in the body.
Stimulates Ovarian Follicles: In women, it stimulates the ovarian follicles to produce estradiol, a hormone that contributes to regulating the menstrual cycle.
Supports Corpus Luteum: It helps the corpus luteum (a hormone-secreting structure that develops in an ovary after an ovum has been discharged) secrete progesterone, preparing the womb for pregnancy.
Acts on Leydig Cells: In men, Chorionic Gonadotropin acts on Leydig cells (cells found adjacent to the seminiferous tubules in the testicle) to produce testosterone and other androgens, which are required for sexual maturation and sperm production.

Pregnancy

Sifasi Aqua 5000 Injection is contraindicated during pregnancy, except for supporting early pregnancy in IVF. If you are pregnant or planning to conceive, ensure to discuss this with your doctor before starting this medicine.

Breastfeeding

Use of Sifasi Aqua 5000 Injection while breastfeeding should only be considered if the benefits outweigh the risks. Always consult your doctor before administering.

Alcohol

There is no known interaction between Sifasi Aqua 5000 Injection and alcohol. However, moderation in drinking alcohol is always advisable when you are on medication.

Liver

With conditions related to liver health, caution is advised while administering Sifasi Aqua 5000 Injection. It's wise to discuss any liver-related concerns with your doctor before starting this medication.

Kidney

If you have a history of kidney health issues, it's a good idea to consult your doctor before using Sifasi Aqua 5000 Injection.

Using Machines & Driving

No specific information exists on whether Sifasi Aqua 5000 Injection can affect your ability to drive or operate machinery.

Allergy

Avoid using Sifasi Aqua 5000 Injection if you're allergic to Human Chorionic Gonadotropin or any other ingredients included in the formulation.

Children

Sifasi Aqua 5000 Injection should only be administered to children and adolescents under medical supervision for specific conditions such as cryptorchidism and delayed puberty due to pituitary deficiency.

Older Patients

Older patients should administer Sifasi Aqua 5000 Injection under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Interactions of Sifasi Aqua 5000 Injection 1ml

Drug-Drug Interactions

Sifasi Aqua 5000 Injection interacts with the following medicines:

Androgens: If taken with Sifasi Aqua 5000 Injection, androgenic medicines like testosterone and dehydroepiandrosterone (DHEA) may have their effects increased, leading to an increased risk of adverse effects.
Anticonvulsants: Medicines such as phenytoin, carbamazepine, and phenobarbital may increase the metabolism of the active ingredient in Sifasi Aqua 5000 Injection, potentially reducing its effectiveness.
Ulcer Medications: Medicines like ranitidine or omeprazole used for treating ulcers could increase the metabolism of the active ingredient, thereby reducing its effectiveness.
Gonadotropin-Releasing Hormone Agonists/Antagonists: Medicines like leuprolide or ganirelix may reduce the response to Sifasi Aqua 5000 Injection.

Drug-Food Interactions

There are no specific known interactions between food and Sifasi Aqua 5000 Injection.

Drug-Disease Interactions

Sifasi Aqua 5000 Injection interacts with the following diseases:

Precocious Puberty: This medication can worsen precocious puberty due to hormonal imbalances.
Prostate Cancer: The injection can worsen symptoms in individuals with prostate cancer or other androgen-dependent neoplasms.
Thyroid or Adrenal Dysfunction: People with these conditions should use this medicine with caution as it may exacerbate their conditions.
Cardiovascular, Renal or Pulmonary Disease: This injection may cause fluid retention, which can exacerbate these conditions.

Dosage of Sifasi Aqua 5000 Injection 1ml

Daily Dose

The daily dosage of Sifasi Aqua 5000 Injection should be administered as prescribed by your doctor. The dosage may vary based on health factors such as the severity of your condition and your response to treatment. It's crucial to adhere to the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

In case of an accidental overdose, you might experience common side effects like nausea, vomiting and abdominal pain. However, don't panic but ensure you inform your doctor about the situation.

Missed Dose

If you have missed a dose of Sifasi Aqua 5000 Injection, administer it as soon as you remember. But if it's nearly time for your subsequent dose, skip the missed one now and return to your normal dosage plan. Increasing your dosage without a doctor's advice is strictly unadvisable.

Always store Sifasi Aqua 5000 Injection in a cool place, ideally between 2°-8°C.
Keep it away from direct sunlight and protect it from moisture.
Ensure that it's out of reach and sight of children.

For women undergoing treatment for infertility, maintain a balanced diet rich in folic acid (like leafy greens) to support follicular development.
For men using the injection to manage conditions such as hypogonadotropic hypogonadism, regular exercise can support testosterone production.

Fact Box

Drug Category	Luteinising Hormone Mimic
Therapeutic Category	Reproductive Health
Available Dosage Types	Injection
Habit Forming	No
Ailment	Infertility, Cryptorchidism

What is the main use of Sifasi Aqua 5000 Injection?

Sifasi Aqua 5000 Injection is primarily used to manage infertility issues in women and certain conditions in men, such as delayed puberty and undescended testes.

How does Sifasi Aqua 5000 Injection work in the body?

This medicine mimics a hormone called luteinising hormone, helping women's ovaries to produce essential hormones and men's testes to produce testosterone, crucial for sexual maturation.

Can Sifasi Aqua 5000 Injection be self-administered at home?

No, this injection should always be administered by a doctor in a clinical setting. It is not meant for self-administration at home.

Can I use Sifasi Aqua 5000 Injection for weight loss?

No, HCG is not approved for weight loss. Its use for this purpose lacks clinical evidence and may lead to serious side effects.

What should I do if I experience severe side effects after administering Sifasi Aqua 5000 Injection?

If you experience severe or concerning side effects after receiving this injection, immediately seek medical attention from your doctor.

Is it safe to use Sifasi Aqua 5000 Injection during pregnancy?

No, except for supporting early pregnancy in IVF cases, this medicine should not be used during pregnancy. Always consult your doctor before using any medication.

Can Sifasi Aqua 5000 Injection be used in women with primary ovarian failure?

No, this medicine is ineffective in women with conditions like premature menopause where ovaries have stopped functioning normally. It is used in women with intact ovarian function.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Saniya K Mulla

Medical Writer & Reviewer | 5 years

MBBS

Check out Editorial Policy

Manufacturer details

212/2, Hadapsar, Off Soli Poonawalla Road, Pune 411028 India

Country of origin: INDIA

References

Chorionic Gonadotropin (Human): Uses, Interactions, Mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09126
NOVAREL® (chorionic gonadotropin) for injection, for intramuscular use Initial U.S. Approval: 1974. (n.d.). https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=ac6918ff-9dc3-40d9-8619-54b26e4bdfc8&type=display
Chorionic gonadotropin (Human). (n.d.). https://www.accessdata.fda.gov/drugsatfda_docs/nda/2000/21-149_Ovidrel_Medr.pdf
Betz, D., & Fane, K. (2023, August 14). Human chorionic gonadotropin. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK532950/

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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