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Hydrochlorothiazide + Nebivolol

Uses of Hydrochlorothiazide + Nebivolol

  • Hydrochlorothiazide + Nebivolol is primarily used to manage high blood pressure in adults and is classified as a combination of a thiazide diuretic, commonly known as a "water pill", and a cardioselective beta-blocker.

  • By lowering blood pressure, this medicine may also help prevent complications such as stroke, heart attack, and kidney issues.

Side effects of Hydrochlorothiazide + Nebivolol

  • Dizziness

  • Lightheadedness

  • Fatigue

  • Headache

  • Nausea

How Hydrochlorothiazide + Nebivolol works

  • Hydrochlorothiazide + Nebivolol is a combination medicine for managing high blood pressure.

  • Hydrochlorothiazide is a diuretic or "water pill". It helps your kidneys to remove excess water and salts from your body, lowering the volume of blood that needs to be pumped, thus reducing blood pressure.

  • Nebivolol is a beta-blocker. It reduces the effect of certain natural substances like adrenaline on the heart and blood vessels, resulting in a slower and less forceful heartbeat. This helps to lessen the pressure with which blood is pumped, thereby lowering blood pressure.

  • These two mechanisms work together to improve blood flow by relaxing and widening the blood vessels, thus effectively managing high blood pressure.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama Ahmed Dental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Hydrochlorothiazide + Nebivolol is available for oral administration, typically presented in tablet form.

Age and Dose Restrictions

  • This medication is intended for adults only. It is not suitable for children or adolescents.

Contraindications

  • Hydrochlorothiazide + Nebivolol is contraindicated in patients with severe bradycardia. It is also contraindicated in patients with heart block greater than first-degree, cardiogenic shock, and decompensated heart failure.

  • The medication should not be used in individuals with sick sinus syndrome unless they have a functioning pacemaker.

  • It is contraindicated in those with severe liver impairment and anuria.

Other Medications to Avoid

  • This combination may interact with other blood pressure medications (such as ACE inhibitors and ARBs), antidepressants (like fluoxetine, and paroxetine), antiarrhythmics (such as amiodarone, and propafenone), antipsychotics (like chlorpromazine), corticosteroids, digoxin, insulin and oral diabetes medications, lithium, NSAIDs (like ibuprofen, naproxen), barbiturates (like phenobarbital), opioids (like morphine), cholestyramine, and colestipol.

Overdose and Missed Dose

  • An overdose of Hydrochlorothiazide + Nebivolol can lead to severe lowering of blood pressure, fainting, slowing of the heart rate, difficulty breathing, dizziness, weakness, dehydration, and electrolyte disturbances. Immediate medical attention is crucial in the event of an overdose.

  • If you miss a dose of this medicine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If experiencing dizziness or lightheadedness from the medication, consider taking it at bedtime to reduce the impact during waking hours.

  • Increasing fluid intake can help manage mild dehydration or dry mouth if these side effects occur.

Use in Driving and Operating Machinery

  • Hydrochlorothiazide + Nebivolol may impair your ability to drive or operate heavy machinery due to potential side effects such as dizziness or fatigue. It is advisable to avoid engaging in such activities until you understand how this medicine affects you.

Use in Pregnancy and Lactation

  • Consult your doctor before using Hydrochlorothiazide + Nebivolol if you are pregnant or breastfeeding. Usually, it is only used if the potential benefits outweigh the potential risks. The medication is not recommended during breastfeeding due to the risk of adverse effects on the nursing infant.

Caution in Other Conditions

  • Caution is advised when using Hydrochlorothiazide + Nebivolol in patients with kidney or liver disease. Adjustments to dosage or close monitoring may be necessary.

  • Individuals with asthma or other breathing disorders should discuss potential risks with their doctor due to possible worsening of these conditions.

Special Dietary and Lifestyle Recommendations

  • Maintain a diet low in salt and fat to help manage high blood pressure effectively alongside taking Hydrochlorothiazide + Nebivolol.

  • Regular physical activity such as walking, cycling, or swimming can help lower blood pressure naturally and complement the effects of this medicine.

  • Monitoring your weight regularly can provide feedback on your health progress and the effectiveness of treatment.

  • Limiting alcohol intake can enhance the effectiveness of blood pressure management strategies while preventing potential interactions with this medication.

  • Implementing stress-reducing techniques like yoga, meditation or deep-breathing exercises can further aid in managing hypertension effectively.

Frequently asked questions

Rare but serious side effects of Hydrochlorothiazide + Nebivolol may include mood changes. If you experience such symptoms, it is crucial to consult your doctor promptly.

There is no effect of Hydrochlorothiazide + Nebivolol on menstruation. If you notice any changes in your menstrual cycle while taking this medication, please consult your doctor.

The use of Hydrochlorothiazide + Nebivolol does not affect appetite. However, if you experience changes in appetite, it is important to discuss this with your doctor.

There is no natural substitute that can precisely replace the specific combination of Hydrochlorothiazide and Nebivolol in managing high blood pressure. It is essential not to switch or stop your prescribed medication without consulting your doctor.

Yes, in rare cases, some people may experience allergic reactions like rash, itching, and swelling while taking Hydrochlorothiazide + Nebivolol. If you show symptoms of an allergic reaction, you should seek medical assistance immediately.

There are no specific food interactions with Hydrochlorothiazide + Nebivolol. However, it's always a good idea to discuss dietary habits with your doctor when starting a new medication.

There is no evidence of dependency or addiction associated with the use of Hydrochlorothiazide + Nebivolol. However, abruptly stopping this medication can worsen chest pain (angina), so always consult your doctor before making any changes.

Terms & Conditions


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