Nebi H 5125 Mg Tablet 10

Nebi H Tablet 10

Aristo Pharmaceuticals Pvt.ltd

Strip of 10 Units

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Composition

Hydrochlorothiazide (12.5 Mg) + Nebivolol (5 Mg)

Nebi-H Tablet is primarily used for managing high blood pressure, a condition also known as hypertension. This medicine is a combination of two active ingredients, making it part of the antihypertensive category of medicines.

In addition to lowering blood pressure, this tablet can also reduce the risk of serious cardiovascular events such as strokes and heart attacks. This makes it a vital tool in maintaining cardiovascular health.

Before you start taking this tablet, it's important to consult your doctor who will guide you on the suitable dosage and frequency. If you have any pre-existing conditions or if you're taking other medicines, you should inform your doctor. Also, be sure to notify your doctor if you notice any unusual side effects while on this medicine. Remember to keep taking the medicine for the entire duration prescribed by your doctor for best results.

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Nebi-H Tablet serves several important medical purposes:

Management of essential hypertension: Nebi-H Tablet is primarily used to manage high blood pressure.
Reduction in risk of cardiovascular events: By lowering blood pressure, it helps reduce the risk of severe heart-related complications, such as strokes and heart attacks.
Use in combination therapy: Nebi-H Tablet can be combined with other antihypertensive agents for enhanced blood pressure control.

Following are the key guidelines on how to take Nebi-H Tablet:

Nebi-H Tablet is taken orally with a glass of water.
Swallow the tablet whole without crushing or breaking it.
Try to take your medication at the same time each day for consistent blood levels and optimal effect.
Do not alter the dosage without consulting your doctor.
Remember not to stop taking this medicine abruptly; always consult your doctor first.

Nebi-H Tablet is taken orally.

Possible side effects of the Nebi-H Tablet include:

Headache
Fatigue
Dizziness
Slow heartbeat, also known as bradycardia: This is when your heart rate is slower than normal.
Stomach pain
Nausea
Diarrhoea
Decreased blood pressure (hypotension): This means that your blood pressure might drop lower than it should be.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Nebi-H Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are a couple of tips to manage certain side effects:

Stomach pain: Avoid taking this medicine on an empty stomach. Try to take it with food or after eating a meal.
Nausea or Diarrhoea: This medicine may be less likely to upset your stomach if you take it with a light snack or milk.

Nebi-H Tablet contains two active ingredients working together to control hypertension:

Nebivolol (5 mg): This ingredient reduces heart rate and the force with which the heart muscle contracts. By doing this, it lessens the workload on your heart and its need for oxygen. Additionally, nebivolol helps widen your blood vessels by stimulating the release of a chemical called nitric oxide from the lining of your blood vessels.
Hydrochlorothiazide (12.5 mg): As a thiazide diuretic, hydrochlorothiazide helps your kidneys get rid of unneeded water and salt from your body through urine. This leads to a decrease in blood volume, which translates into lowered blood pressure. Hydrochlorothiazide also directly relaxes your blood vessels.

By acting in these ways, both components work together to effectively manage high blood pressure.

Pregnancy

Nebi-H Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, ensure to consult your doctor before starting this medicine.

Breastfeeding

Nebi-H Tablet is contraindicated for breastfeeding women. It's essential to discuss with your doctor to understand the potential risks and benefits.

Alcohol

While on Nebi-H Tablet, it would be wise to limit alcohol consumption as it might interfere with the effectiveness of the medication. Always consult your doctor for personalised advice.

Liver

Caution is advised while taking Nebi-H Tablet if you have mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have any liver-related problems, discuss them with your doctor before starting this medicine.

Kidney

If you have a history of kidney problems, caution is advised before using Nebi-H Tablet. Consulting your doctor before taking this medicine is a good idea.

Using Machines & Driving

Nebi-H Tablet may cause dizziness or fatigue in some people. If you experience these effects, avoid driving or operating heavy machinery until you're sure about how the medicine affects you.

Allergy

Nebi-H Tablet is contraindicated in patients who are hypersensitive to either nebivolol or hydrochlorothiazide, or any other components of the medicine. If you have known allergies, discuss them with your doctor first.

Children

Caution is advised while giving Nebi-H Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Nebi-H Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age due to potential liver and kidney issues and other medications they might be on. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Nebi-H Tablet interacts with the following medicines:

CYP2D6 Inhibitors: Medicines such as fluoxetine, paroxetine, and quinidine can increase the levels of nebivolol in your body.
Beta-Blockers (Atenolol) and Calcium-channel Blockers (Amlodipine): These can have an additive effect on your heart rate and contractility when taken with Nebi-H Tablet.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Taking naproxen and ibuprofen with Nebi-H Tablet may reduce its blood pressure-lowering effect and increase the risk of kidney problems.

Drug-Food Interactions

High sodium foods can decrease the effectiveness of the hydrochlorothiazide in Nebi-H Tablet.

Drug-Disease Interactions

Nebi-H Tablet interacts with the following diseases:

Diabetes Mellitus: Nebi-H Tablet can increase blood glucose levels, making it harder to manage diabetes.
Asthma or COPD: People with these conditions should be cautious as nebivolol, one of the components of Nebi-H Tablet, can cause breathing difficulties.

Daily Dose

Take the Nebi-H Tablet as directed by your doctor. The dosage varies based on the severity of your condition and how well you respond to the medicine.

Over Dose

Taking more than the prescribed dosage of Nebi-H Tablet may cause side effects such as dizziness, fatigue, or a slow heartbeat. If these symptoms persist, consult your doctor.

Missed Dose

If you forget to take the Nebi-H Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one.

Keep Nebi-H Tablet in a cool and dry place.
Make sure it's safeguarded from direct light and moisture.
Always keep this medicine out of reach of children.
Don't forget to use Nebi-H Tablet before the expiry date mentioned on the packaging.

If you're using Nebi-H Tablet to manage hypertension, try to limit your daily salt intake. Consuming too much salt can raise your blood pressure, undermining the effects of the medication.
Regular physical activity, such as brisk walking or cycling, can help lower your blood pressure. Aim for at least 150 minutes per week. But before starting any new exercise routine, do consult your doctor.

Fact Box

Drug Category	Beta-blocker, Diuretic
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension

What is Nebi-H Tablet used for?

Nebi-H Tablet is a medicine used to manage high blood pressure, which helps reduce the risks of strokes and heart attacks.

How does Nebi-H Tablet work?

Nebi-H Tablet contains nebivolol and hydrochlorothiazide, which work together to lower blood pressure by reducing heart workload and increasing urine output.

How should I take Nebi-H Tablet?

You should take Nebi-H Tablet exactly as advised by your doctor.

What are the possible side effects of Nebi-H Tablet?

Possible side effects include headache, fatigue, dizziness, slow heartbeat, stomach pain, and changes in sexual desire. Always consult your doctor if these persist.

Who should be cautious when taking Nebi-H Tablet?

Individuals with certain conditions like diabetes, thyroid disorders, liver or kidney dysfunction, and certain heart conditions should consult their doctor before taking this medicine.

Can I take other medicines while on Nebi-H Tablet?

Some medicines can interact with Nebi-H Tablet. Always inform your doctor about all other medicines you are taking before starting this medication.

How should I store Nebi-H Tablet?

Store the tablets at room temperature, protected from light and moisture. Keep out of reach of children.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

23 A, Shah Industrial Estate, Off Veera Desai Rd, Andheri West, Mumbai, Maharashtra 400053

Country of origin: INDIA

References

HYPOLOC PLUS. (n.d.). Package leaflet: Information for the user HYPOLOC PLUS 5 mg / 12.5 mg film-coated tablets Nebivolol / Hydrochlorothiazide. https://www.hpra.ie/img/uploaded/swedocuments/ad7d612b-caee-48be-863e-c716264fcb72.pdf
MICRO LABS LIMITED, INDIA. (n.d.). SUMMARY OF PRODUCT CHARACTERISTICS. https://rwandafda.gov.rw/wp-content/uploads/2024/01/NEBILONG-H-Nebivolol-5mg-and-Hydrochlorothiazide-12.5mg-Tablets-SmPC.pdf
USP. (n.d.). HCTZT:R2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/040735s004,040770s003lbl.pdf
Hydrochlorothiazide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00999
HIGHLIGHTS OF PRESCRIBING INFORMATION. (2007). [Prescribing information]. In BYSTOLIC (pp. 1–7). https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021742s022lbl.pdf
Nebivolol: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB04861

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