Leflunomide

Expert Advice

Dosage Forms Available

• Leflunomide is available for use via oral route in the form of tablets.

Age and Dose Restrictions

• This medicine is meant for adults only.

Contraindications

• Leflunomide is contraindicated in patients with severe hepatic insufficiency, bone marrow dysplasia, severe immunodeficiency states, such as AIDS, and severe, uncontrolled infections.

Other Medications to Avoid

• Leflunomide may interact with immunosuppressive agents (such as methotrexate and tacrolimus), anticoagulants (like warfarin), and hepatotoxic agents (such as paracetamol).

Overdose and Missed Dose

• An overdose of Leflunomide may cause symptoms such as diarrhoea, abdominal pain, skin rash, or jaundice. If an overdose is suspected, contact a doctor immediately.

• If you forget to take this medicine, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of fluids can help manage mild digestive issues like diarrhoea or nausea.

• For mild hair loss, be gentle with your hair and avoid strong shampoos or hair treatments.

Use in Driving and Operating Machinery

• Leflunomide may cause dizziness or tiredness. If affected, avoid driving or operating heavy machinery until you feel well again.

Use in Pregnancy and Lactation

• Leflunomide is contraindicated in pregnancy and breastfeeding. Women of childbearing age must use reliable contraception during treatment and for a period after stopping the medication, as advised by a doctor.

Caution in Other Conditions

• Patients with pre-existing liver disease or impaired renal function should use Leflunomide with caution. Frequent monitoring of these conditions is recommended during treatment. People with a history of tuberculosis or other serious infections should also exercise caution when taking this medicine.

Special Dietary and Lifestyle Recommendations

• To manage rheumatoid arthritis and psoriatic arthritis, reducing the intake of pro-inflammatory foods like red meat, refined carbohydrates, and sugars can be beneficial.

• Including anti-inflammatory foods such as fruits, vegetables, whole grains, fish, and healthy fats in your diet can help in managing inflammation.

• Regular physical activity can help maintain joint flexibility and muscle strength.

• Resting when needed can help manage fatigue associated with rheumatic conditions.

Frequently asked questions

Terms & Conditions