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CompositionRumalef 20 Tablet is used to manage rheumatoid arthritis and psoriatic arthritis by reducing inflammation, pain, and swelling in the joints. This medication helps improve joint function and slows disease progression.
Follow your doctor’s instructions on dosage. Inform your doctor about any existing health conditions or medications. Report any side effects and continue treatment for optimal results.
Rumalef 20 Tablet is used for managing active rheumatoid arthritis and psoriatic arthritis in adults. It helps control inflammation, reduce pain, and improve joint function, supporting overall mobility and quality of life in individuals with these conditions.
Follow these instructions while taking Rumalef 20 Tablet:
Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Do not take more than the dose prescribed by your doctor.
It's crucial not to stop taking this medicine unless advised to do so by your doctor.
Rumalef 20 Tablet is taken orally.
Rumalef 20 Tablet may cause diarrhoea, nausea and vomiting, headache, dizziness, rash and itching, hair loss, and abnormal liver function tests.
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Rumalef 20 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Diarrhoea: Try taking Rumalef 20 Tablet with food or milk.
Nausea and vomiting: If you experience these symptoms, take this medicine after meals to lessen this effect.
Rumalef 20 Tablet contains Leflunomide (20 mg), which acts on your body as follows:
Inhibits Pyrimidine Synthesis: Leflunomide inhibits the synthesis of a substance called pyrimidine, which is needed for the growth and reproduction of cells that divide rapidly. These include the immune cells that cause inflammation in rheumatoid and psoriatic arthritis.
Reduces Inflammation: By reducing the activity of these immune cells, Leflunomide helps to decrease inflammation. This leads to a significant reduction in symptoms such as pain, stiffness, and swelling in the joints.
Slows Disease Progression: By modulating the immune response, this medicine slows the progression of both rheumatoid and psoriatic arthritis, thereby helping to preserve joint function over time.
Rumalef 20 Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.
Rumalef 20 Tablet is not recommended for breastfeeding women. To understand the potential risks and benefits, consult your doctor.
It is advisable to avoid alcohol while taking Rumalef 20 Tablet as it can increase the risk of liver damage. Please discuss with your doctor if occasional moderate alcohol consumption is safe in your case.
Caution is advised while taking Rumalef 20 Tablet in case of liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Rumalef 20 Tablet. This medicine may affect liver function.
Caution is advised before using Rumalef 20 Tablet if you have a history of kidney problems. It's a good idea to consult your doctor before taking this medicine.
There is no evidence to suggest that taking Rumalef 20 Tablet affects your ability to operate machinery or drive safely.
If you are allergic to leflunomide or any other components of Rumalef 20 Tablet, avoid using this medicine. If you experience symptoms like swelling of the face, lips, tongue or throat or difficulty breathing, seek immediate medical attention.
Rumalef 20 Tablet is not recommended for children under the age of 18 years old. Always consult a doctor before giving this medicine to a child.
Older patients should take Rumalef 20 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.
Rumalef 20 Tablet interacts with the following medicines:
Anticoagulants like Warfarin: Rumalef 20 Tablet can increase the risk of bleeding when taken with these medicines.
Cancer Medicines like Methotrexate: These medicines can enhance the risk of liver damage when taken with Rumalef 20 Tablet.
Immunosuppressants like Azathioprine or Cyclosporine: Concomitant use may increase the risk of toxicity.
Rumalef 20 Tablet interacts with the following diseases:
Liver Disease: Patients with pre-existing liver disease should avoid this medicine as it can exacerbate their condition.
Immunodeficiency States: This medicine reduces immune system activity which could worsen conditions in patients with severe immunodeficiency states.
Bone Marrow Dysfunction or Blood Disorders: Patients with significant anaemia, leukopenia, neutropenia or thrombocytopenia should not take this medication as it might further impair their bone marrow function.
Serious Infections: Patients suffering from serious infections should avoid this medicine as it can increase the risk of complications.
The daily dosage of Rumalef 20 Tablet should be taken as instructed by your doctor. Your dosage might vary based on factors like your health condition and how your body responds to the medicine. Always stick to the dosage prescribed by your doctor. For further details regarding the dosage, please consult the package insert.
If you accidentally take more Rumalef 20 Tablets than recommended, you might feel nauseous or dizzy, or you might develop a rash. Try to remain calm and inform your doctor about it.
In case you forget to take your regular dose of Rumalef 20 Tablet, take it as soon as you recall. However, if it's nearly time for your next dose, skip the one you missed and carry on with your usual dosage routine. Always consult your doctor before making any changes to your dosage.
Store Rumalef 20 Tablet at room temperature, ideally below 25°C.
Keep it in its original packaging to protect it from moisture.
Ensure the medicine is out of sight and reach of children.
Always check the expiry date before use and avoid using any tablets past their shelf life.
Engaging in regular low-impact exercises such as swimming or walking can help manage joint stiffness and swelling related to rheumatoid arthritis and psoriatic arthritis. However, always consult your doctor before starting any new exercise regime.
Adopt a balanced diet rich in Omega-3 fatty acids (found in fish, walnuts, and flaxseeds) which have potential anti-inflammatory effects and may assist in managing the symptoms of these conditions.
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Rheumatoid Arthritis, Psoriatic Arthritis |
| Drug Category | Pyrimidine Synthesis Inhibitor |
| Therapeutic Category | Disease-Modifying Antirheumatic Medicine |
Rumalef 20 Tablet is used to manage active rheumatoid arthritis and psoriatic arthritis in adults, reducing symptoms like pain and swelling.
It contains leflunomide, which reduces the activity of immune cells that cause inflammation, thereby managing arthritis symptoms and slowing disease progression.
Avoid alcohol when taking this medicine, as it can increase the risk of liver damage. Always consult your doctor for personalised advice.
If you miss a dose, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one.
Common side effects include diarrhoea, nausea, dizziness, and hair loss. Serious side effects may include liver damage and lung problems.
Over-the-counter pain relievers like paracetamol can be taken with Rumalef 20 Tablet. However, consult your doctor before using other prescription pain medications.
Improvement in symptoms may be noticed after 4 weeks or longer. In some cases, it may take up to 6 months for full benefits.
Check out Editorial Policy
ARAVA. (n.d.). ARAVA Tablets (leflunomide) 10 mg, 20 mg, 100 mg. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020905s022lbl.pdf
Padda, I. S., & Goyal, A. (2023, June 3). Leflunomide. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK557799/
Leflunomide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01097
Leflunomide: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a600032.html
DailyMed. Leflunomide. (n.d.). U. S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2fcef74c-2df9-4b16-b2f6-82c25957a680
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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