Levosalbutamol
ANTIASTHMATICUses of Levosalbutamol
- Levosalbutamol is primarily used to treat the symptoms of Asthma and Chronic Obstructive Pulmonary Disease (COPD).
- Levosalbutamol can be used before exercise to prevent exercise-induced bronchospasm, which is a narrowing of the airways during or after physical activity.
- Levosalbutamol is used to provide quick relief from acute bronchospasm episodes in conditions such as asthma and COPD, helping to alleviate breathing difficulties.
Side effects of Levosalbutamol
- Headache
- Dizziness
- Vomiting
- Nervousness
- Bronchitis (inflammation of the bronchus)
- Increased heartbeat
- Pharyngitis
- Rhinitis
How Levosalbutamol works
- Levosalbutamol works by acting on the beta-2 adrenergic receptors in the smooth muscle of the airways.
- Levosalbutamol selectively stimulates beta-2 adrenergic receptors located in the bronchial smooth muscle. These receptors are part of the sympathetic nervous system.
- When levosalbutamol binds to beta-2 receptors, it activates the enzyme adenylate cyclase. This enzyme converts adenosine triphosphate (ATP) to cyclic adenosine monophosphate (cAMP).
- The increase in cAMP levels leads to a series of intracellular events that result in the relaxation of bronchial smooth muscle.
- The relaxation of the smooth muscle around the airways causes the airways to widen (bronchodilation). This helps to alleviate symptoms such as wheezing, coughing, shortness of breath, and tightness in the chest.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Levosalbutamol can be taken orally (inhalation solution and inhalers).
Age And Dose Restrictions
- The inhalers can be used in children and adults above 4 years. The inhalation solution can be used in children and adults above 6 years.
Contraindications
- It is contraindicated in patients with a history of hypersensitivity to Levosalbutamol or racemic albuterol.
Other Medications To Avoid With This Medicine
- Avoid taking antihypertensives (atenolol, labetalol, and metoprolol), antidepressants (amitriptyline, amoxapine, clomipramine, isocarboxazid and phenelzine), antiarrhythmics (digoxin), adrenergic agonists (epinephrine), diuretics (furosemide), and other bronchodilators (metaproterenol) with Levosalbutamol. These medications may alter the safety and effectiveness of Levosalbutamol.
Overdose And Missed Dose
- Overdose can cause hypertension, increased heart rate, hypokalemia, nervousness, headache, dry mouth, palpitation, nausea, dizziness, fatigue and sleeplessness. These symptoms need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
- If you miss a dose of this medicine, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.
Management Of Side Effects
- Continue taking the medication as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.
Use In Pregnancy And Lactation
- Caution is advised in pregnant and breastfeeding women.
Caution In Other Conditions
- Caution is advised in patients with seizures, hyperthyroidism, high blood pressure, an irregular heartbeat, diabetes, heart, and impaired kidney function.
Special Dietary And Lifestyle Recommendation
- Learn the correct technique of using an inhalation solution and an inhaler to maximise the effectiveness of the medication.
- Minimise exposure to allergens like dust mites, pet dander, pollen, or mold, which can trigger bronchospasm. Keep your living environment clean, and consider using air purifiers if necessary.
- Avoid consuming chilled and refrigerated foods, which can act as a trigger for bronchospasm.
- Avoid exposure to smoke, strong odours, and chemical fumes, as they can irritate the airways and trigger bronchospasm.
- If you're a smoker, quit smoking to manage COPD.
Frequently asked questions
1. How much time does Levosalbutamol take to work?
This medicine works within minutes, providing rapid relief from bronchospasms and improving airflow in the respiratory passages.
2. Does Levosalbutamol increase blood sugar levels?
This medicine may affect blood sugar levels when taken in large doses. Patients with pre-existing diabetes mellitus should inform the doctor before this medicine is prescribed.
3. Is Levosalbutamol a habit-forming medicine?
No, this medicine is not habit-forming and is generally safe when used as directed.
4. Can I drive after taking Levosalbutamol?
This medicine may cause dizziness. Do not drive, operate machinery, or do other activities that require mental alertness or coordination if you experience dizziness after inhaling it.
5. Is Levosalbutamol available over the counter, or do I need a prescription?
This medicine usually requires a prescription and is unavailable over the counter.
6. Does Levosalbutamol affect fertility?
This medicine is not known to have a significant impact on fertility. These medications are primarily used for respiratory conditions and are not associated with fertility-related side effects.
7. Does Levosalbutamol cause dry mouth?
Yes, this medicine may cause dry mouth as a side effect when taken in excess, although it may not occur in everyone.
8. What is the best time to take Levosalbutamol?
The best time to inhale this medicine is typically as your doctor prescribes, often recommended when you experience symptoms of bronchospasm or as part of a regular dosing schedule.
9. Is Levosalbutamol better than Albuterol?
Levosalbutamol (levalbuterol) is considered to have fewer side effects and may be more effective for some patients compared to Albuterol (salbutamol), but the preference varies individually.
10. Is it safe to take Levosalbutamol if I have heart disease?
Caution is advised when taking Levosalbutamol if you have heart disease, as it may cause palpitations or increase heart rate. Always consult your doctor first.
11. As a diabetic, what should I keep in mind while taking Levosalbutamol?
Levosalbutamol may cause an increase in blood sugar levels, so monitor your glucose levels closely and consult your doctor for appropriate adjustments.
12. Is Levosalbutamol good for cough?
Levosalbutamol is primarily used to relieve bronchospasm in conditions like asthma and COPD, not specifically for treating cough.
13. Is Levosalbutamol safe for kids?
Levosalbutamol can be prescribed for children, but the dosage and safety should be closely monitored by a healthcare professional.
14. What is the difference between Salbutamol and Levosalbutamol?
Levosalbutamol is the R-enantiomer of Salbutamol, meaning it is a more refined form that may have fewer side effects and be more effective for some patients.
Levosalbutamol in other salts
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