Mirabegron
Uses of Mirabegron
The primary use of Mirabegron is to manage symptoms of overactive bladder in adults. It belongs to the group of medicines known as beta-3 adrenergic agonists.
Side effects of Mirabegron
High blood pressure
Common cold symptoms
Urinary tract infections
Headache
Constipation
How Mirabegron works
Mirabegron is a medicine that activates beta-3 adrenergic receptors.
It works by selectively stimulating beta-3 receptors present in the muscles of the urinary bladder. These receptors, once stimulated, enable the bladder muscles to relax. This relaxation increases the bladder's capacity to store urine, reducing the urgency and frequency of urination which are characteristic symptoms of an overactive bladder. Mirabegron primarily interacts with beta-3 receptors and has a lower affinity for other beta receptors, which minimises potential cardiovascular side effects.
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Written By
BDS, MDS
Reviewed By
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Expert Advice
Dosage Forms Available
Mirabegron can be taken orally in the form of extended-release tablets and oral suspension.
Age and Dose Restrictions
Mirabegron is prescribed for adults.
Contraindications
Mirabegron is not suitable if you are allergic to it or any of its components. It is also contraindicated for those with severe high blood pressure (SBP ≥ 180 mmHg and/or DBP ≥ 110 mmHg) that is not well controlled with medication and those with bladder outlet obstruction, where the flow of urine from your bladder is blocked. Always consult your doctor before starting this medication.
Other Medications to Avoid
Mirabegron may interact with CYP2D6 metabolised medicines (such as thioridazine, flecainide, propafenone).
It can also interact with digitalis glycoside (like digoxin, digitoxin), so caution should be exercised while using both medications together.
Overdose and Missed Dose
If you accidentally take too much Mirabegron, you may experience symptoms such as a fast heartbeat, palpitations, high blood pressure, and increased urges to urinate. If this happens, seek medical help immediately.
If you forget to take your dose of Mirabegron, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Use in Driving and Operating Machinery
Mirabegron does not usually affect your ability to drive or operate machinery. However, if you feel dizzy or unwell after taking this medicine, do not drive or use machinery until you feel better.
Use in Pregnancy and Lactation
If you are pregnant, plan to become pregnant, or are breastfeeding, talk to your doctor before taking Mirabegron.
Caution in Other Conditions
If you have kidney problems or liver problems, you should use Mirabegron with caution. Your doctor may need to adjust your dose or monitor you more closely.
Special Dietary and Lifestyle Recommendations
While taking Mirabegron, it's important to continue the lifestyle changes recommended by your doctor to manage an overactive bladder.
Frequently asked questions
How long does it take for Mirabegron to start working?
It may take several weeks before you start noticing an improvement in your symptoms. Remember, it's important to continue taking this medicine even if you don't see immediate results.
Can I stop taking Mirabegron if my symptoms improve?
No, do not stop taking this medicine without consulting your doctor. If you stop taking it suddenly, your symptoms may return.
Will taking Mirabegron affect fertility?
The research data does not mention any direct impact of Mirabegron on fertility. Yet, if you have concerns about fertility while taking this medicine, it would be wise to discuss it with your doctor.
Can Mirabegron cause weight gain?
Weight gain is not a common side effect of Mirabegron. If you notice a significant change in your weight, consult your doctor.
Does taking Mirabegron have any effect on sleep?
There is no specific mention in the research data about Mirabegron directly affecting sleep. However, each individual may respond differently to medications, hence if you experience sleep disturbances after starting Mirabegron, please consult your doctor.
Is there a natural alternative to Mirabegron?
There is no natural alternative that works in the same way as Mirabegron. Always consult your doctor before starting any new medication or supplement.
Is Mirabegron a steroid?
No, Mirabegron is not a steroid. It belongs to a class of medicines known as beta-3 adrenergic agonists.
Mirabegron in other salts
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