Pantoprazole
AntacidUses of Pantoprazole
- Pantoprazole is used to treat Gastroesophageal Reflux Disease (GERD).
- It is also used in treating duodenal ulcers and gastric ulcers.
Side effects of Pantoprazole
- Dizziness
- Abdominal pain
- Flatulence
- Headache
- Nausea
- Vomiting
How Pantoprazole works
Pantoprazole, classified as a proton pump inhibitor (PPI), exerts its inhibitory action on the terminal phase of gastric acid production by forming a covalent bond with the (H+, K+)-ATPase enzyme system situated at the secretory surface of the gastric parietal cell. This mechanism results in the suppression of both basal and stimulated gastric acid secretion, independent of the specific stimulus. The covalent binding to the (H+, K+)-ATPase engenders an antisecretory effect that persists beyond 24 hours across all tested doses.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Pantoprazole is available for use via the oral route (delayed-release tablets and granules).
Age and Dose Restrictions
- It is meant for adults and children above 12 years of age.
Contraindications
- In case of an overdose of Pantoprazole, inform your doctor regarding the effects and follow the advice accordingly.
Other Medications To Avoid With This Medicine
- The concurrent use of anticoagulants (clopidogrel, warfarin), azole antifungals (ketoconazole, voriconazole, itraconazole, posaconazole), nucleoside reverse transcriptase inhibitors (nelfinavir, atazanavir), iron supplements, antibiotics (ampicillin, rifampin), cardiac medications (digoxin), and anti-cancer drugs (methotrexate) with Pantoprazole is not recommended. Consultation with a doctor is essential before initiating any prescription or over-the-counter medications.
Overdose and Missed Dose
- In case of an overdose of Pantoprazole, inform your doctor regarding the effects and follow the advice accordingly.
- If you forget a Pantoprazole dose, take it as soon as you remember. But avoid repeating the dose.
Use In Driving And Operating Machinery
- Pantoprazole may affect your ability to drive or operate heavy machinery. Avoid driving if you feel dizzy after taking this combination.
Use in Pregnancy and Lactation
- Pantoprazole is not recommended during pregnancy or breastfeeding.
Caution In Other Conditions
- Individuals with gastroesophageal reflux disease should contemplate lifestyle adjustments, incorporating dietary modifications such as adopting a GERD-friendly diet characterised by an emphasis on low-acid foods, avoidance of spicy and fatty meals, and reduction of portion sizes, all in conjunction with the administration of Pantoprazole.
Special Dietary & Lifestyle Recommendation
- It is best to take this combination before meals.
- Avoid alcohol when you are taking Pantoprazole.
Frequently asked questions
How much time does Pantoprazole take to work?
This medication starts showing its effect within a few hours after consumption.
What warnings and precautions should I take while taking Pantoprazole?
Avoid taking this medication if you experience hypersensitivity or allergic reactions to Pantoprazole. Promptly seek medical advice in such cases.
Can I stop taking Pantoprazole if I feel healthy?
Do not stop taking this medication without consulting your doctor, even if you feel healthy.
Is Pantoprazole safe for patients with kidney or liver issues?
Consult your doctor before taking this medication if you have kidney or liver issues to ensure its safety and proper dosage.
Pantoprazole in other salts
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