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Perindopril

Uses of Perindopril

  • Perindopril is primarily used for managing high blood pressure.

  • It is also used in managing stable coronary artery disease and heart failure.

Side effects of Perindopril

  • Cough

  • Dizziness

  • Fatigue

  • Nausea or vomiting

  • Headache

How Perindopril works

  • Perindopril is an angiotensin-converting enzyme (ACE) inhibitor.

  • It blocks the action of a substance in the body called angiotensin-converting enzyme, which is involved in producing angiotensin II. Angiotensin II is a potent substance that narrows blood vessels and releases hormones that can raise your blood pressure.

  • By preventing the production of angiotensin II, Perindopril allows the blood vessels to relax and widen. This reduces blood pressure and allows the heart to pump blood more efficiently, making it beneficial for managing conditions like hypertension and heart failure.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama Ahmed Dental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Perindopril is available for use via the oral route (tablet).

Age and Dose Restrictions

  • This medication is intended for use by adults. It is not typically prescribed to children or adolescents under the age of 18.

Contraindications

  • Perindopril is contraindicated in patients with a history of angioedema related to previous ACE inhibitor therapy.
  • It is also contraindicated in those with hereditary angioedema.

Other Medications to Avoid

  • Perindopril may interact with diuretics (such as hydrochlorothiazide), potassium supplements or salt substitutes containing potassium, lithium, NSAIDs (like ibuprofen), and other blood pressure medications such as beta-blockers (including atenolol).

Overdose and Missed Dose

  • In case of a Perindopril overdose, symptoms may include severe dizziness, lightheadedness, or fainting. Immediate medical attention should be sought.
  • If you miss a dose of Perindopril, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.

  • If experiencing dizziness or lightheadedness, try resting until the feeling passes.
  • Stay hydrated by drinking plenty of water, which can help alleviate some side effects like headaches or dry mouth.

Use in Driving and Operating Machinery

  • Perindopril may cause dizziness or lightheadedness. You should avoid driving or operating heavy machinery if you experience these side effects.

Use in Pregnancy and Lactation

  • Perindopril is not recommended during pregnancy, particularly in the second and third trimesters due to the risk of harm to the developing fetus.
  • It is also advised against use during breastfeeding. Consult your doctor for more information.

Caution in Other Conditions

  • Patients with renal impairment or kidney problems should use Perindopril cautiously, as dose adjustments may be necessary.
  • Similarly, those with liver issues should be closely monitored while taking this medication due to potential alterations in medicine metabolism.

Special Dietary and Lifestyle Recommendations

  • To support your treatment with Perindopril, maintaining a healthy blood pressure is crucial. Consider adopting a diet low in salt and saturated fats.
  • Regular physical activity can help manage weight and improve heart health.
  • Avoiding smoking and limiting alcohol intake can also benefit cardiovascular health.
  • Managing stress through techniques such as yoga, meditation, or deep breathing exercises can further help in controlling high blood pressure.
  • Keep a regular sleep schedule to help regulate blood pressure and overall health.

Frequently asked questions

No, Perindopril is not a blood thinner. It is an angiotensin-converting enzyme (ACE) inhibitor, used for managing high blood pressure, stable coronary artery disease, and heart failure.

If you are planning to become pregnant, it is advisable to consult your doctor before starting or continuing with Perindopril. ACE inhibitors like Perindopril can cause harm to the developing foetus, particularly during the second and third trimesters of pregnancy.

While it is not common, some people may experience mood changes while taking Perindopril. If you notice any sudden changes in your mood or behaviour while taking this medicine, it would be best to discuss these with your doctor.

Perindopril is taken according to your doctor's recommendation. It is usually taken around the same time each day to maintain consistent levels in your body.

Yes, there are other ACE inhibitors and antihypertensive medications available that may be used as alternatives to Perindopril. However, the choice of alternative medicine is based on individual patient factors and would need to be discussed with your doctor.

Alcohol can enhance the blood pressure-lowering effect of Perindopril causing headache and may increase the risk of other certain side effects. It would be best to discuss this with your doctor.

The blood pressure-lowering effect of Perindopril may start within a few hours of the first dose. However, the full effect may not be seen until after a few weeks of regular use.

Terms & Conditions


Available medicines for PERINDOPRIL
Perigard 4 MG Tablet 10
Perigard 4 MG Tablet 10
Glenmark Pharmaceuticals Ltd.
Pack of 10 Units
₹106.60
MRP ₹130.00
18.00% OFF
Eviper 4 MG Tablet 10
Eviper 4 MG Tablet 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹53.30
MRP ₹65.00
18.00% OFF
Coversyl 4mg Tablet 10
Coversyl 4mg Tablet 10
Serdia Pharmaceuticals (india) Pvt. Ltd.
Pack of 10 Units
₹162.08
MRP ₹197.66
18.00% OFF
Perindolapril Erbumine 8 MG Tablet 10
Perindolapril Erbumine 8 MG Tablet 10
Cipla Ltd.
Pack of 10 Units
₹98.19
MRP ₹119.75
18.00% OFF
Perindprim 4 Tablet 10
Perindprim 4 Tablet 10
Steris Healthcare
Pack of 10 Units
₹64.37
MRP ₹129.00
50.10% OFF
Coversyl 2mg Tablet 10
Coversyl 2mg Tablet 10
Serdia Pharmaceuticals (india) Pvt. Ltd.
Pack of 10 Units
₹138.07
MRP ₹168.38
18.00% OFF
Coversyl 8mg Tablet 10
Coversyl 8mg Tablet 10
Serdia Pharmaceuticals (india) Pvt. Ltd.
Pack of 10 Units
₹204.10
MRP ₹248.90
18.00% OFF
Perindprim 8 Tablet 10
Perindprim 8 Tablet 10
Steris Healthcare
Pack of 10 Units
₹130.38
MRP ₹159.00
18.00% OFF

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