Polymyxin B is primarily used to manage severe infections caused by gram-negative bacteria, especially when other antibiotics are ineffective. It belongs to a group of medications known as cyclic polypeptides.
In addition, Polymyxin B may also be used prophylactically to prevent infection in high-risk patients undergoing certain surgeries or medical procedures.
Injection site reactions such as pain, swelling, and redness
Nausea and vomiting
Diarrhea
Dizziness and vertigo
Skin rash and itching
Polymyxin B is a cyclic polypeptide antibiotic.
It works by binding to the lipopolysaccharide component of the outer membrane of gram-negative bacteria.
This disrupts the integrity and permeability of the bacterial cell membrane, causing leakage of cell contents, which ultimately leads to cell death.
Polymyxin B also potentially neutralizes the toxic effects of the lipopolysaccharide (commonly known as endotoxin).
Therefore, Polymyxin B effectively kills bacteria, making it a bactericidal medicine.
BDS, MDS
BMS, FMC, MD Resident
Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Frequently asked questions
Polymyxin B is predominantly used for managing serious bacterial infections that do not respond to other antibiotics. It belongs to a group of medications known as cyclic polypeptides and primarily targets gram-negative bacteria.
Yes, Polymyxin B can cause an allergic reaction in some individuals. If you experience symptoms such as itching, rash, difficulty breathing, or swelling of the face after using Polymyxin B, you need to seek immediate medical help.
Yes, Polymyxin B can be used prophylactically in high-risk patients undergoing certain surgeries or medical procedures to prevent the onset of infections.
No, Polymyxin B is specifically effective against gram-negative bacteria. It does not work against gram-positive bacteria like MRSA (methicillin-resistant Staphylococcus aureus).
Yes, Polymyxin B may interact with certain medicines. Therefore, always disclose all medications you are taking to your doctor before starting therapy with Polymyxin B.
The time Polymyxin B takes to work depends on the type and severity of the infection. Consult your doctor about when to expect an improvement in your symptoms.
No, Polymycin B is not available over the counter and requires a prescription from a doctor.
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