Recombinant Human Erythropoietin Alfa is primarily used to manage anaemia related to chronic kidney disease, chemotherapy for cancer, HIV treatment with zidovudine, and reducing the requirement for blood transfusions in certain surgical procedures. It belongs to the class of erythropoiesis-stimulating agents.
Additionally, it has been used to treat zidovudine-related anaemia in HIV patients, anaemia due to chemotherapy in cancer patients, and for the reduction of allogeneic blood transfusions in high-risk surgical patients.
Hypertension (high blood pressure)
Headache
Nausea
Vomiting
Diarrhoea
Recombinant Human Erythropoietin Alfa (rHuEPO) is a synthetic form of a hormone called erythropoietin that manages anaemia by stimulating the bone marrow to produce more red blood cells.
It functions by binding with receptors found on immature red blood cell surfaces present in the bone marrow. This interaction promotes these immature cells to multiply and mature into oxygen-carrying red blood cells.
Doctor of Medicine
BMS, FMC, MD Resident
Recombinant Human Erythropoietin Alfa is available for use through the intravenous (in the vein) or subcutaneous (under the skin) routes (injection).
This medication is suitable for both adults and children, as recommended by the doctor.
Recombinant Human Erythropoietin Alfa is contraindicated in patients with allergy to any component of the product.
It is also contraindicated in patients with uncontrolled hypertension.
Recombinant Human Erythropoietin Alfa can interact with antihypertensive medications (such as atenolol and metoprolol).
Overdose of Recombinant Human Erythropoietin Alfa may lead to an increase in haematocrit levels (percentage of red blood cells), potentially causing thrombotic events (blood clots). Immediate medical attention is required.
If you miss a dose of this medicine, administer it as soon as possible. However, if it is near the time for the next dose, skip the missed dose and continue with your usual dosing schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For managing headaches, try to rest and relax.
If you experience nausea, eat little and often, and stick to simple meals.
In case of injection site pain or irritation, try applying a cold pack to the area.
Recombinant Human Erythropoietin Alfa may cause side effects such as dizziness or fainting. If affected, avoid driving or operating heavy machinery.
It is advised to consult your doctor before using this medication if you are pregnant or breastfeeding.
Patients with a history of seizures, renal issues, high blood pressure or thrombotic events should exercise caution when using Recombinant Human Erythropoietin Alfa.
Close monitoring of blood pressure and haematocrit levels is essential for these patients.
Stay well hydrated, especially before and after treatment.
Regular monitoring of blood pressure and blood sugar levels is recommended.
Frequently asked questions
Recombinant Human Erythropoietin Alfa is not directly associated with affecting fertility. However, consult your doctor for detailed information regarding your case.
The frequency of administering Recombinant Human Erythropoietin Alfa is decided by the doctor based on the patient's health condition and response to treatment.
After subcutaneous injection, peak levels of Recombinant Human Erythropoietin Alfa occur within 5-24 hours post-dose. The actual time may vary depending on individual patient factors.
The best time to administer Recombinant Human Erythropoietin Alfa is decided by the doctor. It is usually administered through intravenous or subcutaneous injection under medical supervision.
Recombinant Human Erythropoietin Alfa is a prescription medicine. It is not available over the counter.
Switching from Recombinant Human Erythropoietin Alfa to a natural alternative, especially mid-treatment, is not recommended. It should only be done under the guidance of your doctor.
Recombinant Human Erythropoietin Alfa is not directly associated with affecting sleep patterns. However, if you are experiencing sleep issues, it is recommended to consult your doctor as it could be a sign of underlying complications or side effects.
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