Sofosbuvir + Velpatasvir is primarily used to manage chronic hepatitis C virus infection in adults and children aged 3 years and above. This medicine belongs to the class of antiviral medications.
It is also used in managing various genotypes of HCV infection and is particularly effective in patients with or without cirrhosis.
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Sofosbuvir is an HCV NS5B polymerase inhibitor. It blocks an enzyme called NS5B RNA-dependent RNA polymerase, which the hepatitis C virus needs to copy itself. This stops the virus from multiplying in the body.
Velpatasvir is an HCV NS5A inhibitor. It targets a protein called NS5A, which is used by the hepatitis C virus to replicate itself. By blocking this protein, Velpatasvir further inhibits viral replication.
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The medicine Sofosbuvir + Velpatasvir is available as a fixed-dose combination tablet for oral administration only.
The medicine Sofosbuvir + Velpatasvir is intended for use in adults and children aged 3 years and older.
The medicine Sofosbuvir + Velpatasvir is contraindicated in patients who have severe hypersensitivity to either of its active components, sofosbuvir or velpatasvir.
The medicine is not recommended for patients with moderate or severe hepatic impairment (Child-Pugh B or C).
This combination may interact with potent P-glycoprotein (P-gp) inducers (such as rifampicin and carbamazepine), moderate to potent cytochrome P450 (CYP) inducers (like phenytoin and St. John's wort), certain anticonvulsants (phenobarbital and oxcarbazepine), and antimycobacterial (like rifabutin and rifapentine).
An overdose of this medication could potentially lead to severe adverse health effects. If you suspect an overdose, seek immediate medical attention.
If you miss a dose, take it as soon as you remember. However, if it is close to the time of your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to make up for the missed one.
Most side effects of this medicine are temporary and resolve on their own once the medicine is discontinued. However, if you experience severe side effects or symptoms worsen, consult your doctor immediately.
Drinking plenty of water can help manage some side effects, such as dry mouth and headache.
Resting and avoiding strenuous activities may help manage symptoms like fatigue.
This medication may cause dizziness or sleepiness in some individuals. Hence, it is advisable to avoid driving or operating heavy machinery while on this medication.
The use of Sofosbuvir + Velpatasvir during pregnancy and lactation should be done under the advice and supervision of a doctor.
Patients with renal or hepatic impairment should use Sofosbuvir + Velpatasvir with caution, no dosage adjustments are required in these conditions, but close monitoring is advised.
Maintaining a balanced diet rich in fruits, vegetables, and lean proteins could support overall health when managing chronic hepatitis C virus infection.
Regular, moderate physical activity could help boost your immunity and general well-being.
Maintain good personal hygiene to prevent the spread of the hepatitis C virus.
Frequently asked questions
No, Sofosbuvir + Velpatasvir is not a steroid. It is an antiviral medication specifically used to manage chronic hepatitis C virus (HCV) infection.
Sofosbuvir + Velpatasvir is not directly associated with affecting sleep. However, some people might experience fatigue, which is a common side effect.
Sofosbuvir + Velpatasvir is not associated with affecting human fertility. If you have concerns about this, it is advisable to consult your doctor.
Yes, it is safe to take Sofosbuvir + Velpatasvir daily as directed by your doctor. The medication is indicated for daily use only for a specific period.
The exact time for Sofosbuvir + Velpatasvir to show its effect can vary from person to person and depends on several factors, including the severity and genotype of the HCV infection.
Sofosbuvir + Velpatasvir should be taken as advised by your doctor.
Sofosbuvir + Velpatasvir is a prescription medicine. It is usually not available over the counter.
Sofosbuvir + Velpatasvir in other salts
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