Vericiguat

Dosage Forms Available

• Vericiguat is available for oral administration in the form of tablets.

Age and Dose Restrictions

• It is intended for use in adults of age above 18 years, particularly those with symptomatic chronic heart failure.

Contraindications

• This medicine is contraindicated in patients with known hypersensitivity to Vericiguat.

• It is contraindicated for patients with severe liver impairment.

• It is also contraindicated for concomitant use with other soluble guanylate cyclase (sGC) stimulators.

Other Medications to Avoid

• This medicine can interact with phosphodiesterase type 5 inhibitors (such as sildenafil and tadalafil) and antihypertensive medications (like amlodipine and losartan).

Overdose and Missed Dose

• An overdose may lead to excessive hypotension and anaemia. If you experience symptoms of overdosage, consult your doctor immediately.

• If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.

• Drinking plenty of water can help manage common side effects like headaches.

• Lying down or sitting with your legs elevated can help manage hypotension.

Use in Driving and Operating Machinery

• Vericiguat has been reported to cause dizziness and fatigue. Therefore, caution should be exercised while driving or operating heavy machinery until you know how this medicine affects you.

Use in Pregnancy and Lactation

• This medicine is contraindicated in pregnant women due to the potential risk of fetal harm.

• It is advised to consult a doctor if you are breastfeeding.

Caution in Other Conditions

• Patients with low blood pressure, anaemia, or severe renal impairment should exercise caution when taking Vericiguat.

Special Dietary and Lifestyle Recommendations

• Following a heart-healthy diet that includes plenty of fruits, vegetables, whole grains, lean proteins, and healthy fats can help manage heart failure.

• Limiting salt intake can help prevent fluid accumulation and swelling.

• Regular monitoring of weight can help detect fluid retention early. A sudden weight gain should be reported to a doctor.

• Stress management techniques, such as meditation or yoga, can help improve heart health.