Acnicin 011 Gel 15 Gm

Acnicin Gel 15gm

Alembic Ltd

Tube of 15 GM

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MRP ~~₹212.2~~

₹174

₹14.15/GM

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Composition

Adapalene (0.1 %) + Clindamycin (1 %)

Acnicin Gel is commonly used to manage acne vulgaris. This product is a combination medicine comprising retinoids and antibiotics.

In addition to managing acne vulgaris, this gel also proves beneficial in treating both inflammatory and non-inflammatory acne lesions. Its unique formulation allows it to effectively manage these different types of acne.

Before you start using this medicine, it's essential to consult your doctor who will guide you on the correct dosage and frequency. Make sure to provide your doctor with a complete medical history, including any pre-existing conditions and ongoing medications. Should you notice any side effects while using this medicine, notify your doctor immediately. It's important to continue using the gel for the entire duration prescribed by your doctor for optimal results.

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Acnicin Gel is used for managing:

Acne vulgaris in individuals aged 12 and above
Both inflammatory and non-inflammatory acne lesions
Prevention of follicular keratinization, a process leading to acne formation
Inhibition of microcomedone formation, which are precursors to acne
Reduction in inflammation associated with acne breakouts
Control over Propionibacterium acnes, a bacteria significantly involved in the development of acne

Before applying Acnicin Gel, follow these steps:

Wash the affected area gently with a mild cleanser and warm water.
Pat dry the cleaned area with a soft towel.
Apply a thin layer of the gel on the affected area, preferably at night.
Be careful to avoid contact with your eyes, lips, and mouth. If the gel accidentally gets into these areas, rinse thoroughly with water.
Consult your doctor for further advice on usage.

Acnicin Gel is applied topically.

Acnicin Gel may have the following side effects:

Dry skin
Skin discomfort
Pruritus: This is a medical term for itchiness or an intense itching sensation.
Desquamation: This refers to the shedding or peeling of the outer layers of the skin.
Erythema: This means redness of the skin caused by increased blood flow in superficial capillaries.
Skin irritation

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Acnicin Gel. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Dry skin: Applying a light, fragrance-free moisturiser can help manage this effect.
Skin discomfort: If you experience discomfort after applying Acnicin Gel, try applying it at night before bed.

Acnicin Gel comprises two active ingredients:

Clindamycin (1%): This antibiotic works by binding to the 50S ribosomal subunit in bacteria, thereby inhibiting bacterial protein synthesis. It has been found to be effective against Propionibacterium acnes, a key bacteria involved in causing acne.
Adapalene (0.1%): This retinoid-like compound modulates retinoic acid receptors (RARs) in your body. It normalises follicular keratinisation, which helps reduce inflammation and inhibit the formation of microcomedones, tiny bumps under the skin that later develop into spots.

Pregnancy

Caution is advised while using Acnicin Gel if you are pregnant. It is best to consult your doctor before using this medicine.

Breastfeeding

If you're breastfeeding, it's important to discuss with your doctor whether using Acnicin Gel is a good idea, as it's unknown whether the active ingredients pass into breast milk.

Alcohol

There's no known interaction between Acnicin Gel and alcohol. However, it's always wise to check with your doctor about any potential risks.

Liver

For people with liver problems, always consult your doctor before starting to use Acnicin Gel. This medicine may affect liver function.

Kidney

If you have kidney health issues, it's recommended that you consult your doctor before using Acnicin Gel

Using Machines & Driving

Acnicin Gel is a topical medication and doesn't generally affect your ability to operate machinery or drive.

Allergy

If you're allergic to adapalene, clindamycin, or any other ingredient in the formulation, Acnicin Gel is contraindicated. Contact your doctor if you're unsure about any potential allergies.

Children

Acnicin Gel is not recommended for children under the age of 12 due to insufficient evidence supporting its safety and effectiveness in this group.

Older Patients

Older patients can use Acnicin Gel under medical supervision as they may be more susceptible to its side effects. If you're an older person, discussing your health status with your doctor will help them guide you best.

Drug-Drug Interactions

Acnicin Gel interacts with the following medicines:

Topical Acne Medications: Using Acnicin Gel with other topical acne treatments could cause cumulative irritation. For instance, using it alongside benzoyl peroxide or salicylic acid might lead to excessive dryness or redness.
Oral Antibiotics: Combining Acnicin Gel with oral antibiotics, such as doxycycline or tetracycline, may increase antimicrobial effects, which could potentially lead to antibiotic resistance.
Harsh Skin Products: Soaps, astringents, and abrasive cleansers can aggravate skin irritation when used alongside Acnicin Gel.

Drug-Food Interactions

There are no specific food interactions associated with the usage of Acnicin Gel.

Drug-Disease Interactions

Acnicin Gel interacts with the following diseases:

Hypersensitivity: If you have known hypersensitivity to adapalene or clindamycin, you should avoid using Acnicin Gel as it can trigger allergic reactions.
Regional Enteritis and Ulcerative Colitis: Those diagnosed with regional enteritis or ulcerative colitis should not use this gel due to the presence of clindamycin.
Antibiotic-associated Colitis: As clindamycin is an antibiotic, usage of this gel should be avoided if you have had antibiotic-associated colitis in the past.

Daily Dose

Your daily use of Acnicin Gel should be done as directed by your doctor. This might change based on factors like how severe your condition is and how you respond to the gel. Always stick to the prescribed dosage and don't exceed it without consulting your doctor.

Over Dose

If you accidentally apply too much Acnicin Gel, you might experience some common side effects, such as dry skin, skin discomfort, and skin irritation, more severely. If this happens, rinse the area with water. If the symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to apply Acnicin Gel at the usual time, apply it as soon as you remember. However, if it's nearly time for your next application, skip the missed one and go back to your regular schedule. Never apply extra gel to make up for a missed dose without consulting your doctor.

Store Acnicin Gel at a cool and stable temperature not exceeding 25°C.
Avoid freezing the gel.
Keep it away from direct sunlight and moisture.
Ensure the tube is tightly closed after use.
Always store Acnicin Gel out of reach of children.

Consume a diet rich in antioxidants and vitamin A, which could support skin health. This includes foods like carrots, spinach, and sweet potatoes, which are good for acne-prone skin.
Acnicin Gel can make your skin more sensitive to sunlight and always wear sun protection when outdoors. This could be a hat, sunglasses, or sunscreen with a high SPF rating.

Fact Box

Drug Category	Retinoid-like, Antibiotic
Therapeutic Category	Anti-acne
Available Dosage Types	Gel
Habit Forming	No
Ailment	Acne Vulgaris

What is Acnicin Gel used for?

Acnicin Gel is used to manage acne vulgaris, a common skin condition causing spots and pimples.

How does Acnicin Gel work?

Acnicin Gel combines adapalene and clindamycin, which work together to reduce inflammation and slow down the growth of acne-causing bacteria.

How should I apply Acnicin Gel?

Apply a thin layer of the gel to clean, dry skin, preferably in the evening. Avoid the eyes, lips, and mucous membranes.

Can Acnicin Gel cause any side effects?

Yes, it may cause skin irritation like redness, scaling, dryness or itching. Sun sensitivity may also increase.

Can I use other acne medicines with Acnicin Gel?

It's recommended to avoid other topical acne medications while using Acnicin Gel unless your doctor advises otherwise.

Is it safe to use Acnicin Gel during pregnancy or breastfeeding?

Consult your doctor before using Acnicin Gel if you are pregnant or nursing as its safety has not been fully established.

What precautions should I take while using Acnicin Gel?

Avoid sun exposure and use sunscreen, as this gel may increase sun sensitivity. Also, over-absorption of the medicine into the body can occur, resulting in severe diarrhea. Stop its use in case severe diarrhoea occurs.

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

7c, Bhagoji Keer Marg, Bethany Co-Operative Housing Society, Mahim West, Mahim, Mumbai, Maharashtra 400016

Country of origin: INDIA

References

Adapalene: MedlinePlus Drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a604001.html
Clindamycin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01190
Clindamycin: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a682399.html
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 60164, Adapalene. Retrieved June 7, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Adapalene

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