Ajaduo 255 Mg Tablet 10

Ajaduo 25mg/5mg Tablet 10

Lupin Ltd

Strip of 10 Units

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MRP ~~₹861~~

₹731.85

₹86.10/Units

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Composition

Empagliflozin (25 Mg) + Linagliptin (5 Mg)

AjaDuo 25/5 mg Tablet is primarily used to manage blood sugar levels in adults with type 2 diabetes mellitus. This combination medicine belongs to the antidiabetic class, which helps control high blood sugar levels.

In addition to managing type 2 diabetes, this medicine also aids in reducing the risk of cardiovascular death in adults with pre-existing heart conditions and type 2 diabetes. Moreover, it is a preventive measure against hospitalisation due to heart failure in patients already diagnosed with this condition.

Before starting this tablet, you must consult your doctor and discuss your medical history, including any ongoing medications. If you experience any side effects during the course of this medication, promptly report them to your doctor. For optimal results, it is essential to continue taking the medicine for the entire duration prescribed by your doctor.

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AjaDuo 25/5 mg Tablet is used for the following:

Managing blood sugar levels in adults with type 2 diabetes mellitus
Reducing the risk of cardiovascular death in adults with type 2 diabetes who already have heart disease
Lowering the risk of hospitalisation due to heart failure in adults with existing heart issues

Directions for Use of Ajaduo 25mg/5mg Tablet 10

Follow these instructions while taking AjaDuo 25/5 mg Tablet :

Swallow the tablet whole with a glass of water. Do not chew or crush it.
You can take this medicine with or without food, as per your convenience.
Always stick to the dose recommended by your doctor and do not exceed it.
If you have any concerns or queries, do not hesitate to consult your doctor.

AjaDuo 25/5 mg Tablet is taken orally.

Side Effects of Ajaduo 25mg/5mg Tablet 10

The following are some of the potential side effects you could experience with AjaDuo 25/5 mg Tablet :

Upper respiratory tract infection: This could cause symptoms like a sore throat, cough, or runny nose.
Nasopharyngitis: Commonly known as a cold, it can cause a sore throat, runny nose, sneezing, and fatigue.
Urinary tract infection
Increased urination: You might find yourself needing to go to the toilet more often than usual.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of AjaDuo 25/5 mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Upper respiratory tract infection: Keep hydrated and rest well. Warm liquids can also soothe your throat.
Increased urination: Ensure you stay hydrated by drinking plenty of water throughout the day.

AjaDuo 25/5 mg Tablet comprises two active ingredients:

Empagliflozin (25 mg): This ingredient is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. It reduces glucose reabsorption from your kidneys, leading to increased glucose excretion through urine. This process helps lower plasma glucose levels, effectively managing your blood sugar levels.
Linagliptin (5 mg): As a dipeptidyl peptidase-4 (DPP-4) inhibitor, linagliptin slows down the inactivation of incretin hormones. Incretins are a group of metabolic hormones that reduce blood sugar levels in a glucose-dependent manner. By keeping these hormones active for longer, linagliptin helps reduce both fasting and post-meal blood sugar concentrations.

Pregnancy

If you are pregnant, caution is advised while taking AjaDuo 25/5 mg Tablet. It is not recommended during the second and third trimesters of pregnancy. Always consult your doctor before taking this medicine.

Breastfeeding

Breastfeeding mothers should avoid using AjaDuo 25/5 mg Tablet as there may be a risk to the developing baby. It's best to consult your doctor for advice.

Alcohol

The interaction of AjaDuo 25/5 mg Tablet with alcohol is unknown. Caution is advised. Always consult your doctor before consuming alcohol while taking this medicine.

Liver

AjaDuo 25/5 mg Tablet should be used cautiously if you have liver health issues. Always discuss your liver health status with your doctor before starting this medicine.

Kidney

Caution is advised while taking AjaDuo 25/5 mg Tablet if you have kidney health issues. This medicine is contraindicated in severe renal impairment, end-stage renal disease, or dialysis. Your doctor will guide you based on your health status.

Using Machines & Driving

AjaDuo 25/5 mg Tablet does not interfere with your ability to drive or operate machinery. However, it's always safe to consult your doctor for advice.

Allergy

Do not take this medicine if you have a history of serious hypersensitivity to empagliflozin, linagliptin, or any other ingredients in Ajaduo 25/5 mg Tablet.

Children

AjaDuo 25/5 mg Tablet is not recommended for use in children as its safety and effectiveness have not been established in this age group.

Older Patients

Elderly patients can take AjaDuo 25/5 mg Tablet under medical supervision as they may be more susceptible to its side effects. It's important to ensure renal function is assessed, particularly in elderly patients, before starting this medicine.

Interactions of Ajaduo 25mg/5mg Tablet 10

Drug-Drug Interactions

Diuretics: Empagliflozin in AjaDuo 25/5 mg Tablet can interact with diuretics, like furosemide or hydrochlorothiazide, and can increase the risk of low blood pressure.
CYP3A4 inducers: Medicines such as rifampin can decrease the efficacy of linagliptin in AjaDuo 25/5 mg Tablet. You may need to consider alternative treatments.

Drug-Food Interactions

High-fat meals: Consuming a high-fat meal before taking an AjaDuo 25/5 mg Tablet may increase the medication's absorption, potentially affecting its effectiveness.

Drug-Disease Interactions

Renal disease: If you have severe renal impairment, end-stage renal disease, or are on dialysis, AjaDuo 25/5 mg Tablet is not recommended as it can exacerbate your condition.
Pancreatitis: If you have a history of pancreatitis, use AjaDuo 25/5 mg Tablet cautiously. Linagliptin in AjaDuo has been linked to cases of acute pancreatitis.
Heart failure: Those with a prior history of heart failure or renal impairment should be monitored for signs and symptoms of heart failure while using AjaDuo 25/5 mg Tablet. In case heart failure develops during therapy, consider discontinuation.

Daily Dose

The daily dose of AjaDuo 25/5 mg Tablet should be taken as directed by your doctor. The dosage depends on individual factors, such as the severity of your condition and your response to treatment. Always stick to the prescribed dosage and never exceed it without consulting your doctor. For further details regarding dosage, consult the package insert.

Over Dose

If you happen to take more AjaDuo 25/5 mg Tablet than recommended, you may experience symptoms like excessive thirst or increased urination. It is important to inform your doctor if these symptoms persist.

Missed Dose

If you forget to take a dose of AjaDuo 25/5 mg Tablet, take it as soon as you remember. If you realise this is close to your next scheduled dose, skip the missed one and continue with your regular dosage schedule. Never double up on doses without consulting your doctor.

Store AjaDuo 25/5 mg Tablet at a temperature not exceeding 30°C.
Keep the medicine in a cool, dry place, away from direct sunlight.
Ensure this medicine is out of sight and reach of children.
Always check the expiry date before taking your dose.

As part of managing your type 2 diabetes, aim to maintain a balanced diet. This means consuming controlled portions of carbohydrates and including more high-fibre foods like whole grains, fruits, and vegetables in your meals.
Regular physical activity can help control your blood sugar levels. Try to engage in moderate exercise, such as brisk walking or cycling, for at least 30 minutes each day. Always consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	SGLT2 inhibitor, DPP-4 inhibitor
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	2 diabetes, Cardiovascular disease

What is AjaDuo 25/5 mg Tablet used for?

AjaDuo 25/5 mg Tablet improves blood sugar control in adults with type 2 diabetes when diet and exercise alone are not enough.

How should I take AjaDuo 25/5 mg Tablet?

You should take one AjaDuo 25/5 mg Tablet as prescribed by your doctor.

Can AjaDuo 25/5 mg Tablet cause side effects?

Yes, some common side effects include upper respiratory tract infection, nasopharyngitis, urinary tract infection and increased urination.

Is AjaDuo 25/5 mg Tablet safe during pregnancy?

AjaDuo 25/5 mg Tablet is not recommended during the second and third trimesters of pregnancy. Always consult your doctor.

Can I take AjaDuo 25/5 mg Tablet if I have kidney problems?

If you have severe renal impairment, end-stage renal disease or require dialysis, you should not take AjaDuo 25/5 mg Tablet.

What should I do if I experience a severe allergic reaction to AjaDuo 25/5 mg Tablet?

If you experience a serious allergic reaction to this medicine, discontinue its use immediately and seek prompt medical attention.

Can AjaDuo 25/5 mg Tablet be taken with other medicines for diabetes?

Yes, but it may increase the risk of hypoglycaemia when used with insulin or insulin secretagogues. Always consult your doctor for advice.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: GERMANY

References

MedlinePlus. (2024, April 1). Empagliflozin. Retrieved from https://medlineplus.gov/druginfo/meds/a614043.html
MedlinePlus. (2024, April 1). Linagliptin. Retrieved from https://medlineplus.gov/druginfo/meds/a611036.html
U.S. Food & Drug Administration. (2022). Jardiance (empagliflozin) tablets, for oral use. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/204629s034lbl.pdf
U.S. Food & Drug Administration. (2023). Tradjenta (linagliptin) tablets, for oral use. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/201280s027lbl.pdf

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