Alsita M 50500 Mg Tablet Er 10

Alsita M 50 Tablet 10

Alkem Laboratories Ltd.

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Composition

Metformin (500 Mg) + Sitagliptin (50 Mg)

Alsita-M 50 Tablet is primarily used to manage blood sugar levels in adults diagnosed with type 2 diabetes mellitus. It's a combination medicine that belongs to the class of antidiabetic medicines.

This medication works alongside a balanced diet and regular exercise to enhance blood sugar control. It's particularly beneficial in managing the amount of glucose your body absorbs and produces, thereby helping to maintain a healthy blood sugar balance.

Before you begin taking this medicine, it's crucial to consult your doctor, who can provide a personalised dosage based on your health condition and history. It's equally important to inform your doctor about any pre-existing conditions or other medications you're currently on. If you experience any side effects while on this medicine, promptly report them to your doctor. Remember, for optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Alsita-M 50 Tablet is used for the following:

Improving blood sugar control in adults with type 2 diabetes mellitus
Reducing glucose production by the liver
Decreasing intestinal absorption of glucose
Enhancing insulin sensitivity and regulating insulin levels after eating

Directions for Use of Alsita M 50 Tablet 10

Swallow the tablet whole with a glass of water.
Avoid splitting, crushing or chewing the tablet.
Take this medicine once daily with a meal, preferably in the evening.
Do not exceed your current daily dose when switching from immediate-release metformin to Alsita-M 50 Tablet without consulting your doctor first.

Remember, these instructions are general guidelines. Always consult your doctor for specific directions based on your health and treatment needs.

Alsita-M 50 Tablet is taken orally.

Alsita-M 50 Tablet may have the following common side effects:

Upper respiratory tract infection: This refers to an infection in any part of the upper respiratory system, which includes your nose, throat, and sinuses.
Nasopharyngitis: You might commonly know this as a cold. It's an infection that leads to a sore throat, runny nose, and sneezing.
Diarrhoea
Headache

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Alsita-M 50 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Consume plenty of water and healthy fluids to avoid dehydration.
Headache: If you notice headaches after taking this medicine, consider taking it at night before bed.

Alsita-M 50 Tablet comprises two active ingredients:

Metformin (500 mg): This component is part of a group of medicines known as biguanides. Metformin operates in three major ways to regulate your blood sugar levels: it reduces glucose production by the liver, decreases the absorption of glucose in your intestines, and enhances insulin sensitivity so that your body can better utilise the glucose present in your blood.
Sitagliptin (50 mg): Classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor, sitagliptin works by maintaining the levels of insulin your body produces after a meal. It does this by inhibiting a particular enzyme in your body known as DPP-4, which leads to increased levels of certain hormones that stimulate insulin production. This results in a reduction of glucose production in your liver.

Pregnancy

Caution is advised while taking Alsita-M 50 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Sitagliptin, one of the ingredients in Alsita-M 50 Tablet, is excreted in human milk. Metformin, on the other hand, is excreted in small amounts. It's essential to consult your doctor before using this medicine while breastfeeding.

Alcohol

Alsita-M 50 Tablet and alcohol can interact, as alcohol can increase the effect of metformin on lactate metabolism. Therefore, you should avoid excessive alcohol intake.

Liver

If you have liver problems, discuss them with your doctor before starting Alsita-M 50 Tablet. This medicine could affect liver function.

Kidney

Alsita-M 50 Tablet should be taken with caution if you have kidney issues because metformin is substantially excreted by the kidneys. Ensure to consult your doctor before starting this medicine.

Using Machines & Driving

There's no specific information about the impact of Alsita-M 50 Tablet on your ability to drive or use machines. However, it's always sensible to see how you react to a new medicine before undertaking such tasks.

Allergy

Serious hypersensitivity reactions have been reported in some patients treated with sitagliptin, a component of Alsita-M 50 Tablet. If you are allergic to any ingredient in this medicine, discuss it with your doctor.

Children

The safety and effectiveness of Alsita-M 50 Tablet have not been established in children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Alsita-M 50 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Alsita-M 50 Tablet interacts with the following medicines:

Carbonic Anhydrase Inhibitors: If you're taking medications like topiramate, zonisamide, or acetazolamide, these may increase the risk of lactic acidosis when taken with Alsita-M 50 Tablet. Your doctor might recommend more frequent monitoring.
Medicines reducing Metformin clearance: Certain medicines like ranolazine, vandetanib, dolutegravir, and cimetidine can increase metformin accumulation in your body. Discuss the benefits and risks of concurrent use with your doctor.
Alcohol: Consuming alcohol while on Alsita-M 50 Tablet can multiply the effect of metformin on lactate metabolism. Hence, excessive alcohol intake is not advised.
Insulin or Insulin Secretagogues: The risk of low blood sugar (hypoglycaemia) may be increased when Alsita-M 50 Tablet is combined with insulin or insulin secretagogues like sulfonylurea. A lower dose may be required to minimise this risk.

Drug-Food Interactions

There are no specific food interactions associated with Alsita-M 50 Tablet.

Drug-Disease Interactions

Alsita-M 50 Tablet interacts with the following diseases:

Kidney Disorders: Metformin in Alsita-M 50 Tablet can lead to a rare but serious complication called lactic acidosis, particularly in patients with kidney disorders.
Vitamin B12 Deficiency: Regular use of Alsita-M 50 Tablet could potentially lower vitamin B12 levels in your body, so it's important to keep an eye out for any signs of deficiency.
Hypersensitivity Reactions: If you have a history of severe allergic reactions, do inform your doctor as there have been reports of serious hypersensitivity reactions in patients treated with sitagliptin, one of the components of Alsita-M 50 Tablet.

Daily Dose

You should take your daily dose of Alsita-M 50 Tablet as directed by your doctor. This dose can vary depending on factors like the severity of your condition and how you respond to the medicine. Always stick to the dosage prescribed by your doctor. For additional details, please read the package insert.

Over Dose

If you accidentally take more than the prescribed dose of Alsita-M 50 Tablet, you may experience common side effects more intensely. Don't panic, but do consult your doctor to discuss any symptoms that might occur.

Missed Dose

If you forget to take a dose of Alsita-M 50 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Don't increase your dosage without discussing this with your doctor.

Keep Alsita-M 50 Tablet stored at a controlled room temperature of 20-25°C.
Ensure the medicine is well protected from excessive moisture.
Always keep this medicine in its original packaging until it's time to take it.
Make sure to store the product out of the reach and sight of children.
Don't forget to check the expiry date before taking Alsita-M 50 Tablet.

Try to maintain a healthy, balanced diet rich in fibre. This can help manage your blood sugar levels, which Alsita-M 50 Tablet is designed to control.
Regular exercise is beneficial for managing type 2 diabetes. Aim for at least 30 minutes of moderate-intensity activity, like brisk walking, on most days of the week.

Fact Box

Drug Category	DPP-4 Inhibitor, Biguanide
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is Alsita-M 50 Tablet used for?

Alsita-M 50 Tablet is prescribed to improve blood sugar control in adults with type 2 diabetes, alongside a balanced diet and regular exercise.

How do the ingredients in Alsita-M 50 Tablet work?

Metformin reduces glucose production by the liver and improves insulin sensitivity, while Sitagliptin regulates insulin levels after eating, both helping to manage blood sugar levels.

How should I take Alsita-M 50 Tablet?

You must take the medicine as directed by your doctor.

What precautions should I take while using Alsita-M 50 Tablet?

Watch out for symptoms of lactic acidosis, pancreatitis and hypersensitivity reactions. If any signs occur, stop taking the medicine and consult your doctor immediately.

Can Alsita-M 50 Tablet interact with other medicines?

Yes, interaction can occur with medicines like carbonic anhydrase inhibitors, alcohol, and insulin secretagogues. Discuss all medications you're taking with your doctor before starting Alsita-M 50 Tablet.

Is it safe to use Alsita-M 50 Tablet during pregnancy or while breastfeeding?

The safety of using this medicine during pregnancy or breastfeeding isn't established. Consult your doctor if you're pregnant, planning to conceive or are breastfeeding.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Alkem House, Senapati Bapat Marg, Lower Parel, Mumbai Maharashtra- 400013

Country of origin: INDIA

References

DailyMed. (n.d.). Metformin hydrochloride- Metformin hydrochloride tablet, film coated. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b857eccf-b9ff-45ba-8241-f47f5caada2a
FDA. (2012). FDA Drug Safety Communication: Updated FDA review on incretin mimetics. Retrieved 1 April 2024, from https://www.fda.gov/downloads/drugs/drugsafety/ucm280360.pdf
FDA. (n.d.). Highlights of prescribing information. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/021995Orig1s053lbl.pdf
MedlinePlus. (n.d.). Metformin. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a606023.html
Metformin: A medicine to treat type 2 diabetes. (2022, March 25). Nhs.Uk.
https://www.nhs.uk/medicines/metformin/

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