Canditral Sb 130 Capsule 10

Glenmark Pharmaceuticals Ltd.

BOTTLE of 30 Units
STRIP of 10 Units

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Old MRP ₹299.5

MRP ~~₹280.78~~

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Composition

Itraconazole (130 Mg)

Strength:

65 MG 50 MG 130 MG

Canditral SB 130 Capsule is used to treat fungal infections such as blastomycosis and histoplasmosis. It also helps manage other fungal infections, including aspergillosis, especially when the patients are intolerant of or not responding to amphotericin B therapy. Certain dermatologic fungal infections, like tinea corporis, tinea cruris, and tinea pedis, can also be addressed with this medicine. This medicine belongs to the class of synthetic triazole antifungal agents.

The dosage and frequency of this medication should be strictly guided by your doctor. Make sure to inform your doctor about any pre-existing medical conditions or ongoing medications before starting this medicine. If any side effects arise while on this medication, immediately notify your doctor. For optimal results, continue taking this medicine for the duration prescribed by your doctor.

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Canditral SB 130 Capsule is used to manage aspergillosis, particularly in patients who can't tolerate or respond to amphotericin B therapy. It is also used to treat pulmonary and extrapulmonary blastomycosis, histoplasmosis (including chronic pulmonary disease), and dermatomycoses like tinea corporis, tinea cruris, and tinea pedis.

Here's how you should take Canditral SB 130 Capsule:

Always swallow the capsule whole with a meal.
Do not chew or crush the capsule.
Avoid taking antacids or other gastric acid suppressors within 2 hours of taking Canditral SB 130 Capsule as these may reduce its absorption.

Canditral SB 130 Capsule is taken orally.

Below are some common side effects of Canditral SB 130 Capsule:

Nausea
Vomiting
Diarrhoea
Abdominal pain
Dyspepsia (indigestion)
Dizziness

Managing the Side Effects:

Most side effects are temporary, generally mild, and resolve upon discontinuing the use of Canditral SB 130 Capsule. However, if you experience serious side effects or worsening of any symptoms, consult your doctor.

Here are a couple of tips to manage some common side effects:

Diarrhoea: Try taking Canditral SB 130 Capsule with food to lessen the impact on your digestive system.
Dyspepsia: If you have indigestion, taking this medicine after meals could help reduce this effect.

Canditral SB 130 Capsule contains itraconazole (130 mg), which works in the following ways:

Inhibits ergosterol synthesis: Itraconazole acts by blocking the synthesis of ergosterol, a crucial component of fungal cell membranes.
Increases cell membrane permeability: The inhibition of ergosterol synthesis disrupts the structure and function of the cell membrane, leading to increased permeability.
Triggers leakage and cell death: The increased permeability causes leakage of cellular contents, ultimately causing cell death.
Broad-spectrum antifungal action: Itraconazole exhibits a broad spectrum of action against various fungi, including Blastomyces dermatitidis, Histoplasma capsulatum, Aspergillus flavus, and A. fumigatus.

Pregnancy

Is it safe to use the Canditral Sb 130 Capsule during pregnancy?

Canditral SB 130 Capsule is not recommended if you are pregnant. It's crucial to discuss this with your doctor before starting this medicine.

Breastfeeding

Is it safe to consume Canditral Sb 130 Capsule during breastfeeding?

Canditral SB 130 Capsule should not be taken if you're breastfeeding. Always consult your doctor to understand the potential risks and benefits.

Alcohol

Is it safe to drink alcohol while taking Canditral Sb 130 Capsule?

Caution is advised if you are taking Canditral SB 130 Capsule with alcohol. It is best to consult your doctor before taking this medicine.

Liver

Is it advisable to take Canditral Sb 130 Capsule when experiencing liver problems?

Use Canditral SB 130 Capsule with caution if you have liver problems, as itraconazole, its active ingredient, is extensively metabolised in the liver. Make sure to discuss your liver health with your doctor before starting this medicine.

Kidney

Is it advisable to consume Canditral Sb 130 Capsule when experiencing kidney problems?

Caution is advised when using Canditral SB 130 Capsule if you have a history of kidney issues. Consult your doctor before taking this medicine.

Using Machines & Driving

Is it safe to operate heavy machinery or drive when using the Canditral Sb 130 Capsule?

As Canditral SB 130 Capsule may cause headache or dizziness, caution is advised when driving or operating machinery. If you experience these side effects, it's best to avoid such activities.

Allergy

Are there any specific conditions that should be considered before taking the Canditral Sb 130 Capsule?

Canditral SB 130 Capsule should not be taken if you have known hypersensitivity to itraconazole or any of the capsule excipients. If you have any known allergies, discuss them with your doctor before starting this medicine.

Children

Is Canditral Sb 130 Capsule suitable for infants or children?

Canditral SB 130 Capsule is not recommended for children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Is Canditral Sb 130 Capsule suitable for older patients?

Older patients should take Canditral SB 130 Capsule under medical supervision, as they may be more susceptible to its side effects. Caution is advised for patients over 70 years of age.

Drug-Drug Interactions

Canditral SB 130 Capsule interacts with these medicines:

CYP3A4 inhibitors: This includes antibiotics like clarithromycin and protease inhibitors like ritonavir. These medicines can increase the levels of Canditral SB 130 Capsule in your body, enhancing its effectiveness as well as its side effects.
CYP3A4 inducers: Medicines such as rifampin and phenytoin can reduce the levels of Canditral SB 130 Capsule in your system, thereby reducing its efficacy.
Certain CYP3A4 substrates: Medicines like triazolam, midazolam, felodipine, nisoldipine, lurasidone, and eplerenone should not be taken with Canditral SB 130 Capsule, as they can potentially lead to serious side effects.

Drug-Food Interactions

While there are no significant food interactions with this medicine, Canditral SB 130 Capsule should be taken with a full meal to ensure optimal absorption.

Drug-Disease Interactions

Canditral SB 130 Capsule interacts with these diseases:

Congestive heart failure: People with this condition must avoid taking Canditral SB 130 Capsule as it can worsen their condition.
Liver disease: If you have liver disease, use Canditral SB 130 Capsule with caution. The medicine is extensively metabolised in the liver and may require dose adjustments. Regular monitoring of liver function during treatment is recommended.

Daily Dose

Your doctor will prescribe the daily dose of Canditral SB 130 Capsule taking into consideration your specific medical condition and how you respond to treatment. Ensure that you adhere strictly to this prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you have taken more than the prescribed dose, you may experience nausea, vomiting, or abdominal pain, which are common symptoms of an overdose. In such cases, notify your doctor.

Missed Dose

In case you forget to take a dose of Canditral SB 130 Capsule, take it when you remember. However, if it's nearly time for your next dose, then skip the one you missed and continue with your regular dosage schedule. Never adjust the dosage without consulting your doctor.

Keep your Canditral SB 130 Capsule in a cool, dry place where the temperature stays between 15°C and 30°C.
Avoid direct light and moisture.
Keep the medicine out of reach of children.

Since Canditral SB 130 Capsule manages fungal infections, maintaining good personal hygiene is essential. Regularly wash your hands and body, and keep your surroundings clean.
Eating a balanced diet helps boost your immune system. Include plenty of fruits, vegetables, lean proteins, and whole grains in your daily diet.

Fact Box

Available Dosage Types	Capsule
Habit Forming	No
Ailment	Blastomycosis, Histoplasmosis, Aspergillosis
Drug Category	Antifungal
Therapeutic Category	Antifungal Medication

What is Canditral SB 130 Capsule used for?

Canditral SB 130 Capsule is used to treat various fungal infections in different parts of the body.

What types of fungal infections can Canditral SB 130 Capsule manage?

It can manage systemic fungal infections like blastomycosis, histoplasmosis, aspergillosis, and skin infections such as tinea corporis, tinea cruris, and tinea pedis.

How should I take Canditral SB 130 Capsule?

You should swallow the capsule whole with a full meal for optimal absorption. Do not open, crush, or chew the capsule.

Can I take antacids while using Canditral SB 130 Capsule?

Antacids may reduce the absorption of itraconazole, so they should be taken at least 2 hours before or after taking Canditral SB 130 Capsule.

Are there any side effects of Canditral SB 130 Capsule?

Yes, common side effects include nausea, vomiting, abdominal pain, headache, and rash. If severe side effects occur, consult your doctor immediately.

Is it safe to use Canditral SB 130 Capsule if I have heart disease or liver problems?

Canditral SB is contraindicated in patients with congestive heart failure. Use with caution in patients with liver impairment; periodic monitoring is advised.

How should I store Canditral SB 130 Capsule?

Store the medicine at room temperature, between 15°C to 30°C. Keep it away from heat and moisture.

Last Updated On 06 Aug. 2025 | 10:33AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 9 years

Doctor of Medicine

Reviewed by

Dr. Osama Ahmed

Medical Content Writer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Glenmark House, HDO-Corporate Building, Wing-A, B.D. Sawant Marg, Chakala Off. Western Express Highway, Andheri (East), Mumbai, Maharashtra, 400099 India

Country of origin: INDIA

Expiry on or after: February 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

U.S. Food and Drug Administration. (2018, Dec). Tolsura label. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208901s000lbl.pdf
U.S. Food and Drug Administration. (2018, Dec). Tolsura - other review. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2018/208901Orig1s000OtherR.pdf
DrugBank Online. (2024, May 23). Itraconazole. https://go.drugbank.com/drugs/DB01167
AHFS Patient Medication Information. (2023, Apr 15). MedlinePlus drug information - itraconazole. MedLine. https://medlineplus.gov/druginfo/meds/a692049.html
Tripathi, K. D. (2013). Antifungal Drugs. In Essentials of Medical Pharmacology (7th ed., p. 794).
Kurn, H., & Wadhwa, R. (2022, April). Itraconazole. In StatPearls [Internet]. NIH National Library of Medicine, National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK557874/
De Beule, K., & Van Gestel, J. (2001). Pharmacology of itraconazole. Drugs, 61 Suppl 1, 27–37. https://doi.org/10.2165/00003495-200161001-00003

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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