Canditral Sb 50 Capsule 10

Canditral Sb Capsule 10

Glenmark Pharmaceuticals Ltd.

Strip of 10 Units

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Composition

Itraconazole (50 Mg)

Strength:

65 MG 50 MG 130 MG

Canditral SB Capsule is classified as an antifungal medication. It is prescribed for treating various fungal infections, catering to immunocompromised and non-immunocompromised patients. These infections include blastomycosis, whether pulmonary or extrapulmonary, histoplasmosis in various forms, and aspergillosis, both pulmonary and extrapulmonary.

This capsule is also used in non-immunocompromised patients to treat onychomycosis involving both toenails and fingernails due to dermatophytes (tinea unguium).

Before using this capsule, you must notify your doctor if you have kidney or liver issues, as well as heart problems like heart failure. This capsule is not advisable if your immune system is compromised.

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Canditral SB Capsule is included in the following conditions:

Both pulmonary and extrapulmonary forms of Blastomycosis
Histoplasmosis, including chronic cavitary pulmonary disease and disseminated nonmeningeal histoplasmosis
Pulmonary and extrapulmonary aspergillosis, especially in patients intolerant of amphotericin B therapy
Onychomycosis [Toenail and fingernail involvement due to dermatophytes (tinea unguium)].

Directions for Use of Canditral Sb Capsule 10

Don't crush or break this capsule. Just swallow as it is.
It's a good idea to take them with some food. This can help your body absorb the medicine better.
Try to take the capsule at the same time every day. This helps the medicine work more effectively.

Canditral SB Capsule is taken orally.

Common side effects of Canditral SB Capsule include

Stomach pain
Nausea
Headache

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing Canditral SB Capsule. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

Canditral SB capsule contains the following component:

Itraconazole (50 mg): It is an azole that interferes with the synthesis of ergosterol, a crucial component of fungal cell membranes. This disruption weakens the fungal cell membrane, making it more susceptible to damage. By inhibiting ergosterol production, itraconazole inhibits fungal growth. Without a stable cell membrane, fungi struggle to maintain their structural integrity and reproduce. Itraconazole further disrupts fungal cell function by affecting various enzymes and processes. This damages the fungal cell's ability to carry out essential functions, ultimately leading to its death.

Pregnancy

This medicine should only be used during pregnancy if prescribed by a doctor. It is essential to consult your doctor before taking this medication while pregnant.

Breastfeeding

This capsule is generally not recommended for breastfeeding women because a small amount of this medicine can pass into breast milk. It's advisable to consult your doctor before taking it while breastfeeding.

Alcohol

It is advisable to avoid alcohol if you are taking this capsule to avoid unwanted side effects.

Liver

Inform your doctor before taking this medicine if you have a history of liver problems; its use is not recommended.

Kidney

Exercise caution when considering Canditral SB Capsule if you have renal issues; consult your doctor before using it.

Using Machines & Driving

Avoid driving or heavy work if you experience dizziness or drowsiness after taking this capsule.

Allergy

Avoid taking Canditral SB Capsule if you are allergic to itraconazole.

Children

Consult your doctor before using this capsule if you are below 18 years of age, as it is not recommended for children.

Older Patients

Elderly patients (aged 60 years and above) should exercise caution when taking Canditral SB Capsule. It is recommended to inform your doctor before using this medication.

Drug-Drug Interactions

Canditral SB Capsule may interact with the following medications

Antiarrhythmics like digoxin, dofetilide, quinidine, or disopyramide, when taken alongside this capsule, may result in elevated levels of these drugs in the bloodstream.
Anticonvulsants such as carbamazepine, when taken with this capsule, can lead to the risk of increased plasma concentration of these medications.
Anti-HIV agents like indinavir, ritonavir, saquinavir, and maraviroc can elevate the plasma concentration of anti-HIV agents when taken with this capsule.
Antineoplastics like busulfan, docetaxel, and vinca alkaloids may lead to higher levels of these drugs in the blood when taken with this capsule.
Antipsychotics such as pimozide, when used concomitantly with this capsule, can lead to increased plasma concentration of antipsychotics.
Benzodiazepines like alprazolam, diazepam, midazolam, or triazolam, may have enhanced plasma concentration when taken with this capsule.
Calcium channel blockers like nisoldipine, felodipine, or verapamil may have elevated levels in the body when taken with this capsule.
Gastrointestinal motility agents like cisapride may increase plasma concentration when taken concomitantly with this capsule.
HMG CoA-reductase inhibitors such as atorvastatin, cerivastatin, lovastatin, and simvastatin can have increased plasma concentrations when taken with this capsule.
Immunosuppressants like cyclosporine, tacrolimus, or sirolimus may have increased plasma concentration when taken with this capsule.
Oral hypoglycemics like repaglinide may have an effect on their plasma concentration when taken with this medicine.
Opiate analgesics like fentanyl or levacetylmethadol (evomethadyl) may have increased plasma concentration when taken with this medication.
Polyene antifungals like amphotericin B may have elevated levels when taken with this capsule.
Anticonvulsants, like carbamazepine and phenobarbital, may have decreased plasma concentration when taken with this capsule.

Drug-Disease Interactions

Canditral SB Capsule can interact with conditions/diseases, including

Cardiac dysrhythmias: This capsule may pose a risk of exacerbating cardiac dysrhythmias.
Hearing loss: For individuals with hearing loss, particularly related to medications affecting the inner ear, Canditral SB Capsule should be taken cautiously.
Neuropathy: This capsule may aggravate the condition.
Kidney issues: This medicine may worsen kidney problems.
Liver problems: This capsule can aggravate liver problems.
Congestive heart failure: This medicine can increase the risk of heart failure.
Peripheral oedema: This capsule may impact individuals experiencing peripheral oedema, a condition characterised by the swelling of extremities.
Pulmonary oedema: For individuals with pulmonary oedema, a condition involving fluid accumulation in the lungs, the use of this capsule should be approached cautiously.

Daily Dose

The daily dose of this capsule should be taken as your doctor prescribes. The dosage may change based on individual factors such as age, the condition's severity, and treatment response.

Over Dose

In case of an accidental overdose of Canditral SB Capsule, seek immediate medical help by contacting your doctor.

Missed Dose

If you miss a dose of Canditral SB Capsule, take it as soon as you remember. However, avoid repeating the dose.

The storage instructions for Canditral SB Capsule are as follows:

This capsule should be stored at room temperature, at 25°C.
Please protect it from light and moisture.
Keep away from children.
Do not use this medicine after the expiry date has passed.

Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
Avoid walking barefoot in damp areas like changing rooms and gym showers to prevent fungal infections.
Resist the urge to scratch the affected skin area, which can spread the infection to other body parts.
Avoid sharing towels, combs, bedsheets, shoes, or socks with others.
Ensure you regularly wash your bed sheets and towels to keep them clean and free from potential fungal spores.

Fact Box

Drug Category	Azole
Therapeutic Category	Antifungals
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Fungal infections

Is Canditral SB Capsule steroid or not?

Canditral SB Capsule is not a steroid.

Is Canditral SB Capsule suitable for ringworms?

Yes, it is suitable for treating fungal infections, including ringworm.

How many days to use the Canditral SB Capsule?

Your doctor's prescription should determine the duration of use and the best time to take this capsule.

What is the best time to take the Canditral SB Capsule?

The best time to take Canditral SB Capsule is usually with or immediately after meals. This helps the body better absorb the capsule. Remember to follow your doctor’s instructions and take it at the same time each day for effective results.

Does Canditral SB Capsule cause skin irritation?

While skin irritation is a possible side effect of this medication, it may not occur in everyone, and its severity can vary from person to person. Consult your doctor if you encounter skin irritation or other unusual side effects.

Last Updated On 08 Mar. 2024 | 6:11AM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

References

Highlights of prescribing information anaphylaxis and hypersensitivity ... (n.d.-b). https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022484S000lbl.pdf
U.S. National Library of Medicine. (n.d.-c). Itraconazole: Medlineplus drug information. MedlinePlus. https://medlineplus.gov/druginfo/meds/a692049.html
Itraconazole - StatPearls - NCBI Bookshelf. (n.d.-c). https://www.ncbi.nlm.nih.gov/books/NBK557874/
Patient information: Itraconazole - Manchester University NHS ... (n.d.-e). https://mft.nhs.uk/app/uploads/sites/10/2021/11/Itraconazole-NAC-PIL.pdf
K.D. Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page 794
Mint Pharmaceuticals Inc Health Canada https://pdf.hres.ca/dpd_pm/00044442.PDF

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