Cidmus 200 Mg Tablet 7

Cidmus 200mg Tablet 7

Dr. Reddys Laboratories Ltd

Strip of 7 Units

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Composition

Sacubitril (97 Mg) + Valsartan (103 Mg)

Cidmus 200mg Tablet is primarily used for managing certain types of chronic heart failure. This tablet is a combination medicine, belonging to the class of medicines known as angiotensin receptor neprilysin inhibitors (ARNIs).

In addition to its main use, it aids in improving heart function and reducing the workload on the heart, therefore assisting in easing symptoms related to the condition. This medication has shown effectiveness in managing symptomatic chronic heart failure (NYHA Class II-IV) in adults with reduced ejection fraction and is also indicated for use in paediatric patients aged one year and older.

Before you start taking this medicine, consult your doctor about your current health status including any pre-existing conditions or ongoing medications. If you observe any side effects while on this medicine, inform your doctor immediately. It is crucial to continue taking this medicine as prescribed by your doctor for optimal results.

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Cidmus 200mg Tablet is used for the following:

Management of symptomatic chronic heart failure in adults with reduced ejection fraction.
Helping adults suffering from New York Heart Association (NYHA) Class II-IV heart failure symptoms.
Managing symptomatic heart failure with systemic left ventricular systolic dysfunction in children aged one year and older.

Directions for Use of Cidmus 200mg Tablet 7

Here's how you should take Cidmus 200mg Tablet:

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Cidmus 200mg Tablet is taken orally.

Taking Cidmus 200mg Tablet might cause the following side effects:

Hypotension: This means your blood pressure might go down.
Hyperkalaemia: This refers to a condition where the level of potassium in your blood is higher than normal.
Cough
Dizziness
Renal failure: This means that your kidneys might not function as well as they should.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Cidmus 200mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips for managing minor side effects:

Dizziness: Avoid activities your doctor has advised against and follow their recommendations.
Hypotension: If you feel light-headed or faint, seek advice from your doctor.

Cidmus 200mg Tablet contains two active ingredients:

Sacubitril (97 mg): Sacubitril gets converted into LBQ657 upon consumption. This substance inhibits an enzyme called neprilysin that reduces natriuretic peptides, substances that relax blood vessels, increase sodium excretion, and decrease blood volume.
Valsartan (103 mg): Valsartan belongs to the category of angiotensin II receptor blockers (ARB). It functions by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict thereby increasing blood pressure. Consequently, it helps relax blood vessels and reduce blood pressure making it easier for the heart to pump blood.

The collaboration of both these components aids in improving heart function and reducing the workload on the heart.

Pregnancy

Cidmus 200mg Tablet can cause harm to the developing foetus. It should be discontinued as soon as possible when pregnancy is detected. Before taking this medicine, it's best to consult your doctor.

Breastfeeding

Breastfeeding is not recommended while you are on this medication. It is advisable to consult your doctor before taking Cidmus 200mg Tablet if you're a lactating mother.

Alcohol

Caution is advised while consuming alcohol during the medication. Please consult your doctor for more information.

Liver

If you have moderate liver problems, you might need dose adjustments while taking Cidmus 200mg Tablet. This medicine isn't recommended for severe liver diseases. Be sure to discuss your liver health with your doctor before starting this medicine.

Kidney

Taking Cidmus 200mg Tablet may require caution if you have severe kidney impairment. Make sure to discuss any history of kidney problems with your doctor before taking this medicine.

Using Machines & Driving

Cidmus 200mg Tablet may cause side effects like dizziness which could affect your ability to drive or operate machinery. Avoid driving or using heavy machinery until you know how the medication affects you.

Allergy

Don't take Cidmus 200mg Tablet if you've ever had an allergic reaction to sacubitril or valsartan, or if you've had angioedema related to previous therapy for high blood pressure.

Children

Please consult your doctor before giving this medicine to a child.

Older Patients

Older patients might be more susceptible to side effects of Cidmus 200mg Tablet and should take it under medical supervision. Your doctor will guide you based on your health status if you're above 70 years of age.

Drug-Drug Interactions

Cidmus 200mg Tablet interacts with the following medicines:

ACE inhibitors: Medicines like enalapril or lisinopril may interact with this tablet, potentially increasing the risk of high potassium levels in your blood (hyperkalaemia). You should avoid taking Cidmus 200mg Tablet within 36 hours of the last dose of an ACE inhibitor.
Potassium-sparing diuretics: These medications, such as spironolactone, can increase the level of potassium in your blood when taken with Cidmus 200mg Tablet.
NSAIDs: Medicines like ibuprofen and naproxen can reduce the blood pressure-lowering effects of Cidmus when taken together.
Statins: Certain cholesterol-lowering medicines, such as atorvastatin and simvastatin, may interact with Cidmus 200mg Tablet and cause changes in medicine effects or side effects.

Drug-Food Interactions

There are no specific food interactions with Cidmus 200mg Tablet.

Drug-Disease Interactions

Cidmus 200mg Tablet interacts with the following diseases:

Liver disease: Patients with moderate hepatic impairment should exercise caution while using this medication as it could exacerbate their condition.
Renal Impairment: Patients with severe renal dysfunction may require dose adjustments while using Cidmus 200mg Tablet. Regular monitoring of kidney function is recommended for these patients.

Daily Dose

The daily dosage of Cidmus 200mg Tablet should be taken as recommended by your doctor. The dosage can vary based on factors such as response to treatment and the severity of the condition. Always adhere to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you accidentally take more Cidmus 200mg Tablet than prescribed, you might experience symptoms such as dizziness, low blood pressure, and an increase in potassium levels in your blood. If these symptoms persist, inform your doctor.

Missed Dose

If you forget to take a dose of Cidmus 200mg Tablet, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular schedule. Never adjust your dosage without consulting your doctor.

Keep Cidmus 200mg Tablet at room temperature, ideally below 30°C.
Store it in its original package to shield it from moisture.
Always keep this medicine out of reach of children.
Make sure you use Cidmus 200mg Tablet before its expiry date.

Since Cidmus 200mg Tablet manages chronic heart failure, a diet low in salt and saturated fats can help manage your condition better. This means eating more fruits, vegetables, whole grains and lean proteins.
Regular physical activity is also beneficial. However, don't start a new exercise routine without consulting your doctor, as the right level of activity will depend on the severity of your heart condition.

Fact Box

Drug Category	Angiotensin receptor neprilysin inhibitor
Therapeutic Category	Heart failure management
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Chronic heart failure, left ventricular systolic dysfunction

What is Cidmus 200mg Tablet used for?

Cidmus 200mg Tablet manages chronic heart failure in by improving heart function and reducing the heart's workload.

How does Cidmus 200mg Tablet work?

Cidmus contains sacubitril and valsartan. Sacubitril increases peptides that relax blood vessels, while valsartan blocks a hormone that can tighten them, thus easing the heart's job.

Should I eat before taking Cidmus 200mg Tablet?

You must follow the timing guidelines prescribed by your doctor while taking this medicine.

What are the side effects of Cidmus 200mg Tablet?

Potential side effects include low blood pressure, high potassium levels, cough, dizziness, and kidney failure. If you notice any side effects, consult your doctor immediately.

Can Cidmus 200mg Tablet interact with other medications?

Yes, it can interact with ACE inhibitors, potassium-sparing diuretics, statins, and certain other medications. Consult your doctor before starting any new medication.

Is Cidmus 200mg Tablet safe for pregnant or breastfeeding women?

No, this medicine can harm the foetus if taken during pregnancy and may pass into breast milk. It's best to consult your doctor.

What if I accidentally take too much of Cidmus 200mg Tablet?

Overdose symptoms may include low blood pressure, high potassium levels, and kidney problems. Seek immediate medical help if you suspect an overdose.

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Bigshare Services Pvt. Ltd. 306, Right Wing, 3rd Floor Amrutha Ville, Opp.Yash Hyderabad - 500082 Telangana

Country of origin: INDIA

References

Novartis Pharmaceuticals Corporation. (2021). Highlights of prescribing information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/207620s018lbl.pdf
Entresto. (n.d.). Entresto Summary of product characteristics. https://www.ema.europa.eu/en/documents/product-information/entresto-epar-product-information_en.pdf
CARMADA. (n.d.). Sacubitril and Valsartan tablets [Report]. https://www.sanofi.in/dam/jcr:2e79c610-7644-4d4c-bf51-1651a1804410/Carmada%20PI-%20Valsartan+Secubitril-Annotated-Nov%202023.pdf
Sacubitril: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09292
Valsartan: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00177
Kido, K., Colvin, B. M., Szymanski, T. W., & Guglin, M. (2022). Sacubitril/Valsartan Off-Label uses for heart failure. Journal of Cardiac Failure, 28(7), 1185–1201. https://doi.org/10.1016/j.cardfail.2022.03.348

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