Clobenate Gm 005205 Cream 10 Gm

Clobenate GM Cream 10gm

Ind Swift Laboratories Ltd

TUBE of 20 GM
TUBE of 10 GM

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MRP ~~₹92.85~~

₹46.33

₹9.29/GM

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*MRP inclusive of all taxes

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Composition

Clobetasol Propionate (0.05 %) + Miconazole (2 %) + Neomycin (0.5 %)

Clobenate-GM Cream is primarily used to manage various fungal and bacterial skin infections. It's a combination medicine consisting of corticosteroids, azole antifungals, and aminoglycoside antibiotics.

In addition to its main use, this medicine is also beneficial for inflammatory skin conditions where there's a suspected secondary infection or risk of one. Conditions such as inflamed cutaneous mycoses, bacterial skin infections, dermatitis flares with secondary infection, and psoriasis with secondary infection can be managed with this cream.

Before you begin using this medicine, ensure that you consult your doctor, who will advise on the appropriate dosage and frequency based on your condition.

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Clobenate-GM Cream is used to treat various skin infections, including ringworm, jock itch, and athlete's foot. It helps manage itching, redness, and rashes caused by these fungal infections. Additionally, it is effective against bacterial skin infections, providing relief in conditions like eczema and psoriasis.

Directions for Use of Clobenate GM Cream 10gm

To use Clobenate-GM Cream, follow these steps:

Make sure the affected skin area is clean and dry.
Apply a thin film of the cream to the affected skin areas twice a day.
Rub the cream gently into your skin.
Wash your hands before and after applying the cream.
Avoid touching your eyes, mouth, or any other mucous membranes after applying the cream.

Clobenate-GM Cream is applied topically.

When you use Clobenate-GM Cream, you may experience some of the following side effects:

Burning sensation
Skin irritation, itching, and rash
Dry skin, peeling, and tingling
Erythema (redness of the skin due to increased blood flow in the superficial capillaries)
Folliculitis (Inflammation or infection of hair follicles, which can show up as small red bumps or pimples around the hair follicles.)

Managing the Side Effects:

Most side effects are temporary and generally harmless and resolve upon discontinuing the use of Clobenate-GM Cream. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Burning sensation: If you experience this effect, try applying the cream at night so that you can sleep through most of it.
Skin irritation, itching, and rash: To help reduce these effects, consider applying a moisturiser before using Clobenate-GM Cream.

Clobenate-GM Cream contains three active ingredients that work together to manage skin conditions:

Clobetasol Propionate (0.05%): This is a potent corticosteroid with anti-inflammatory properties. It works by inducing lipocortins, proteins that inhibit the production of inflammation-causing substances in the body.
Miconazole (2%): An azole antifungal, miconazole inhibits the synthesis of ergosterol, an essential component of fungal cell walls. This increases the permeability of these walls, causing leakage of cellular contents.
Neomycin (0.5%): As an aminoglycoside antibiotic, neomycin stops bacterial growth by binding to their 30S ribosomal subunit – an essential part of protein synthesis. This action results in bacteria misreading mRNA and the subsequent inhibition of protein synthesis.

Pregnancy

If you are pregnant, it is advised to exercise caution while using Clobenate-GM Cream. Always consult your doctor before starting this medication.

Breastfeeding

If you are breastfeeding, be cautious about using Clobenate-GM Cream. It's best to discuss this with your doctor to understand the potential risks and benefits.

Alcohol

Interactions between Clobenate-GM Cream and alcohol are unlikely, as this is a topical medication. However, always maintain a healthy lifestyle while on medication.

Liver

If you have liver health issues, be careful when using Clobenate-GM Cream. Discuss any liver-related concerns with your doctor before starting this medicine, as it may affect liver function.

Kidney

Caution is advised when using Clobenate-GM Cream if you have a history of kidney problems. Consulting your doctor before taking this medicine is always a good idea.

Using Machines & Driving

Clobenate-GM Cream is a topical skin treatment, so it's unlikely to affect your ability to drive or operate machinery. However, always ensure you're in good health before engaging in such activities.

Allergy

Clobenate-GM Cream should not be used if you have known allergies to any of its components. If you are unsure about potential allergic reactions, consult your doctor before applying this cream.

Children

Clobenate-GM Cream should not be used in children under 12 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should use Clobenate-GM Cream under medical supervision, as they may be more susceptible to its side effects. Caution is advised for patients over 70 years of age due to potential liver and kidney health issues.

Drug-Drug Interactions

Clobenate-GM Cream interacts with the following medicines:

Corticosteroids: Using other topical corticosteroids along with Clobenate-GM Cream may increase the risk of hormonal imbalances, like Hypothalamic-Pituitary-Adrenal (HPA) axis suppression.
Anaesthetics and Muscle Relaxants: The neomycin in Clobenate-GM Cream can enhance the neuromuscular blocking action of certain anaesthetics and muscle relaxants, such as vecuronium or atracurium.

Drug-Food Interactions

There are no known interactions between Clobenate-GM Cream and any specific foods. Since this cream is for external use, it's generally unaffected by what you eat or drink.

Drug-Disease Interactions

Clobenate-GM Cream interacts with the following diseases:

Liver Disease: If you have liver disease, be cautious while using this cream, as your body might be more prone to the adverse effects of the cream.
Renal Impairment: Individuals with renal impairment should use this cream with caution. Neomycin, one of its ingredients, is mostly excreted unchanged in urine. So, renal impairment might affect how your body handles neomycin.

Daily Dose

The daily dosage of Clobenate-GM Cream should be determined by your doctor. It depends on factors like the severity of your condition and your response to the medication.

Over Dose

If you accidentally apply more Clobenate-GM Cream than recommended, you may experience some common side effects like skin irritation or redness. If these symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to apply Clobenate-GM Cream at the scheduled time, do it as soon as you remember. But if it's nearly time for your next application, skip the missed dose and continue with your usual schedule. Never apply extra cream to make up for a missed dose without consulting your doctor.

Store Clobenate-GM Cream in a cool, dry place, ideally at a temperature below 25 °C.
Shield it from direct sunlight and avoid freezing the cream.
Always keep the tube tightly closed after use.
Ensure Clobenate-GM Cream is kept out of reach of children.
Always check the expiry date before applying the cream; never use it past its expiration date.

If you have skin conditions like eczema or psoriasis managed by Clobenate-GM Cream, try to include foods rich in Omega-3 fatty acids, such as fish and flaxseeds, in your diet. These can help reduce inflammation and support skin health.
Maintain good hygiene practices to prevent secondary infections. Regularly wash and dry your skin, especially the area where you apply the cream. Avoid sharing towels or other personal items that come into contact with your skin.

Fact Box

Drug Category	Anti-inflammatory, Antifungal, Antibacterial
Therapeutic Category	Dermatological
Available Dosage Types	Cream
Habit Forming	No
Ailment	Cutaneous mycoses, Eczema, Psoriasis

What is Clobenate-GM Cream used for?

Clobenate-GM Cream is used to manage various fungal and bacterial skin infections. It helps reduce inflammation, itching, and swelling while inhibiting the growth of fungi and bacteria.

How does Clobenate-GM Cream work?

Clobenate-GM Cream contains three active ingredients that provide anti-inflammatory, antifungal, and antibacterial actions. It works by reducing inflammation, halting fungal growth, and stopping bacterial growth.

How should I apply Clobenate-GM Cream?

You should apply a thin layer of Clobenate-GM Cream to the affected skin areas as directed by your doctor.

Are there any side effects of using Clobenate-GM Cream?

Some people may experience local side effects like skin irritation, dryness, or a burning sensation.

Are there any conditions where I shouldn't use Clobenate-GM Cream?

Yes, you should not use Clobenate-GM Cream if you have hypersensitivity to its ingredients or suffer from viral skin infections, certain fungal or parasitic infestations, or certain types of acne.

Can I use Clobenate-GM Cream while pregnant or breastfeeding?

Clobenate-GM Cream falls under Pregnancy Category C; it should only be used during pregnancy if the benefits outweigh the risks. If you're breastfeeding, use it with caution. Always consult your doctor before using this cream if you are pregnant or breastfeeding.

How should I store my Clobenate-GM Cream?

Store your cream in a cool, dry place below 25 °C, protected from direct sunlight.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 9 years

Doctor of Medicine

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

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Manufacturer details

4/10 IndSCO 850, Shivalik Enclave, N.A.C. Manimajra, Chandigarh - 160101 INDIAustrial Estate Gorwa, Vadodara - 390001

Country of origin: INDIA

References

DailyMed. (n.d.). Clobetasol propionate- clobetasol propionate cream. U.S. National Library of Medicine. Retrieved on 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=fb29b17b-96af-4a78-bc91-83cf8c5c2b1d&type=display
MedlinePlus. (2022). Miconazole Topical. U.S. National Library of Medicine. Retrieved on 1 April 2024, from https://medlineplus.gov/druginfo/meds/a682274.html
NHS UK. (2022, October 27). Clobetasol: A steroid medicine to treat swelling and itching. nhs.uk. https://www.nhs.uk/medicines/clobetasol/
National Library of Medicine. (2022, November 15). Miconazole topical: MedlinePlus drug information. MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a618061.html

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