Clopitab 150 Tablet 10

Clopitab 150 Tablet is used for the following:

• Prevention of atherothrombotic events in patients with a history of heart disease or stroke.

• Management of peripheral arterial disease, a condition where blood vessels in the legs are blocked.

• Preventing atherothrombotic and thromboembolic events in patients suffering from acute coronary syndrome.

• Reducing the risk of stent thrombosis in patients who have undergone percutaneous coronary intervention, a procedure to open blocked coronary arteries.

• Use in patients who have undergone bypass surgery for treating blockages in their coronary arteries.

When taking Clopitab 150 Tablet, follow these steps:

• Swallow the tablet whole with a glass of water.

• Avoid breaking or chewing the tablet.

Clopitab 150 Tablet is taken orally.

Clopitab 150 Tablet contains clopidogrel (150 mg), and its activity in the body can be understood as follows:

• Hepatic Biotransformation: Clopidogrel is a prodrug, meaning it requires transformation in the liver, specifically via an enzyme called CYP2C19, into an active metabolite that can exert its effects.

• Inhibition of Platelet Aggregation: The active metabolite of clopidogrel selectively and irreversibly inhibits the binding of a molecule called adenosine diphosphate (ADP) to its receptor on platelets. This stops the activation of a complex of proteins (glycoprotein GPIIb/IIIa complex) on the platelets, which normally leads to platelets sticking together. By preventing this, clopidogrel effectively reduces the risk of blood clots forming and causing heart attacks, strokes, and other cardiovascular events.

• Keep your Clopitab 150 Tablet stored at room temperature, ideally between 15 to 30°C.

• Make sure the storage area is dry and not exposed to direct sunlight or moisture.

• Always keep this medicine out of the reach of children.

• Remember to use it before its expiry date for maximum efficacy.

• If you've been prescribed Clopitab 150 Tablet due to heart-related conditions, remember to follow a heart-healthy diet. This includes plenty of fruits, vegetables and whole grains, whilst limiting saturated fats and salt.

• Regular exercise can also help manage your condition. Strive for moderate-intensity activities like brisk walking or cycling for at least 30 minutes most days of the week, but do consult your doctor before starting any new exercise routine.