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CompositionDapaglyn M 500 Tablet is used to treat type 2 diabetes mellitus in adults, especially when diet and exercise alone are not enough. It combines dapagliflozin and metformin to help lower blood sugar levels by increasing glucose excretion and improving insulin sensitivity. This medicine also helps reduce the risk of diabetes-related complications, including kidney, heart, and nerve problems. Always take this medicine as prescribed by your doctor.
Dapaglyn M 500 Tablet is used to manage type 2 diabetes by improving blood sugar control and reducing the risk of complications, including neuropathy, retinopathy, kidney problems, and cardiovascular events such as heart attack or heart failure.
Follow these instructions while taking Dapaglyn M 500 Tablet:
Ingest the tablet whole with a meal.
Do not crush or chew the tablet.
Ensure that you take it at the same time every day for consistent blood levels.
Do not alter your dose without consulting your doctor.
It's crucial not to discontinue this medicine without speaking to your doctor first.
Dapaglyn M 500 Tablet is taken orally.
Dapaglyn M 500 Tablet can cause side effects such as nausea, vomiting, diarrhoea, urinary tract infections, increased urination, flatulence, skin rash, taste changes, and genital fungal infections. Nasopharyngitis, an inflammation of the nose and throat, may also occur.
Most side effects are temporary and generally harmless and resolve upon discontinuing the use of Dapaglyn M 500 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are a couple of tips for managing some common side effects:
Nausea: Try taking Dapaglyn M 500 Tablet with food to mitigate this effect.
Diarrhoea: Consider adjusting the timing of when you take this medicine. If it's causing diarrhoea during the day, try taking it at bedtime instead.
Dapaglyn M 500 Tablet contains two active ingredients:
Dapagliflozin (10 mg): As a sodium-glucose co-transporter 2 (SGLT2) inhibitor, dapagliflozin works by blocking the re-absorption of glucose in the kidneys. This leads to an increase in glucose excretion through urine, helping to lower blood sugar levels.
Metformin (500 mg): This is a biguanide that works on several fronts in your body to control blood sugar levels. Metformin reduces glucose production in the liver and enhances insulin sensitivity, which means your body responds better to insulin. It also improves glucose uptake and utilisation by your body's cells.
Together, dapagliflozin and metformin help maintain optimal blood sugar levels in patients with type 2 diabetes.
If you're pregnant, caution is advised when taking Dapaglyn M 500 Tablet. It's best to consult your doctor before using this medicine.
For those breastfeeding, Dapaglyn M 500 Tablet should be used with care. Always have a discussion with your doctor about potential risks and benefits.
While taking Dapaglyn M 500 Tablet, excessive alcohol consumption should be avoided, as it may increase the risk of poor blood sugar control, leading to serious complications like diabetes ketoacidosis.
If you have liver problems, be cautious when starting Dapaglyn M 500 Tablet as it may influence liver function. Make sure to discuss your health condition with your doctor.
Dapaglyn M 500 Tablet is not recommended for severe kidney problems or if you're on dialysis. If you have a history of kidney issues, it's crucial to consult your doctor before using this medicine.
No specific precautions are mentioned regarding machine operation or driving while on the Dapaglyn M 500 Tablet. However, always be aware of how the medicine affects you before engaging in such activities.
Dapaglyn M 500 Tablet is contraindicated if you're allergic to Dapagliflozin, Metformin, or any other ingredients in the tablet. Consult your doctor if you have known hypersensitivities before starting this medication.
Caution is advised while giving Dapaglyn M 500 Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.
Older patients should take Dapaglyn M 500 Tablet under medical supervision, as they may be more susceptible to its side effects. Special caution is advised for patients above 70 years of age who might also have liver and kidney issues and might be on other medications. Your doctor will guide you based on your health status.
Dapaglyn M 500 Tablet interacts with the following medicines:
Diuretics: Dapaglyn M 500 Tablet, when taken alongside diuretics like furosemide or hydrochlorothiazide, may increase the risk of dehydration and low blood pressure.
Insulin or Insulin Secretagogues: Medicines such as insulin glargine or glimepiride can interact with Dapaglyn M 500 Tablet, potentially leading to an increased risk of low blood sugar (hypoglycaemia).
Medicines affecting Kidney Function: Medicines like ibuprofen or naproxen may affect kidney function, which can interfere with the excretion process of Dapaglyn M 500 Tablet.
Certain food items may interact with the Dapaglyn M 500 Tablet.
High-fat Meals: Consuming high-fat meals while taking Dapaglyn M 500 Tablet may slow down the absorption of the medication, potentially affecting its efficacy.
Dapaglyn M 500 Tablet interacts with the following diseases:
Diabetes Type 1: Individuals with diabetes type 1 should be cautious when using Dapaglyn M 500 Tablet, as it may affect blood sugar levels differently compared to those with type 2 diabetes.
Diabetic Ketoacidosis: Dapaglyn M 500 Tablet may worsen diabetic ketoacidosis in patients, a serious condition that develops when there is a severe lack of insulin in the body, leading to the breakdown of fat as a source of energy instead of glucose.
Kidney Disease: Patients with kidney disease should exercise caution when taking Dapaglyn M 500 Tablet as it could exacerbate their condition.
Liver Disease: Liver disease sufferers need to be careful as Dapaglyn M 500 Tablet can affect liver function, potentially worsening their condition.
Your doctor will prescribe the daily dose of Dapaglyn M 500 Tablet based on your individual health condition and how you respond to treatment. It's vital that you take the medicine as instructed and avoid exceeding the prescribed dose without consulting your doctor.
If you accidentally take more than the prescribed dose of Dapaglyn M 500 Tablet, you might experience overdose symptoms such as nausea, vomiting, or diarrhoea. In such cases, it's wise to get in touch with your doctor for advice.
If you miss a dose of Dapaglyn M 500 Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Please do not alter your dosage without consulting your doctor.
Store the Dapaglyn M 500 Tablet at room temperature, ideally between 20 to 25 degrees Celsius.
Keep away from direct heat, light and moisture to maintain its effectiveness.
Always keep this medicine out of reach of children and pets for safety reasons.
Use Dapaglyn M 500 Tablet before the expiry date printed on the packaging.
Maintain a balanced diet low in sugar and high in fibre. This can help manage your blood sugar levels along with taking Dapaglyn M 500 Tablet.
Regular physical activity like walking or cycling for at least 30 minutes a day can aid in managing your type 2 diabetes by improving your body's ability to use insulin.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Type 2 Diabetes Mellitus |
| Drug Category | SGLT2 Inhibitor, Biguanide |
| Therapeutic Category | Antidiabetic |
Dapaglyn M 500 Tablet reduces glucose production in your liver and increases glucose excretion from your kidneys, managing blood sugar levels.
Take the tablet orally with food at the same time daily, as prescribed by your doctor, for consistent blood sugar control.
If you miss a dose, take it when you remember. If it's near the next dose time, skip the missed one.
No, don't stop taking Dapaglyn M 500 Tablet without consulting your doctor as it might lead to uncontrolled blood sugar levels.
Common side effects include nausea, vomiting, diarrhoea, genital fungal infections, urinary tract infections, increased urination, and low blood sugar.
Avoid excessive alcohol consumption while on this medication, as it may cause serious side effects.
Yes, when taken as prescribed by a doctor, it's generally safe for long-term use with regular health monitoring.
Check out Editorial Policy
HIGHLIGHTS OF PRESCRIBING INFORMATION. (2014). [Press-release]. XIGDUO XR. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/205649s008lbl.pdf
DailyMed - METFORMIN ER 500 MG tablet METFORMIN ER 750 MG tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b857eccf-b9ff-45ba-8241-f47f5caada2am.nih.gov/dailymed/lookup.cfm?setid=b857eccf-b9ff-45ba-8241-f47f5caada2a
DailyMed - FARXIGA- dapagliflozin tablet, film coated. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=72ad22ae-efe6-4cd6-a302-98aaee423d69
Dapagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06292
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
Phadke, U., Gopal, J., Biswas, K., Birla, A., Prasad, A., & Joshi, P. (2023). FRI649 ADMIRE: Assessing dapagliflozin and metformin as an initial regimen in diabetes mellitus for enhanced glucose control. Journal of the Endocrine Society, 7(Supplement_1). https://doi.org/10.1210/jendso/bvad114.868
Bailey, C. J., Gross, J. L., Hennicken, D., Iqbal, N., Mansfield, T. A., & List, J. F. (2013). Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled 102-week trial. BMC Medicine, 11(1). https://doi.org/10.1186/1741-7015-11-43
Cheng, L., Fu, Q., Zhou, L., Fan, Y., Liu, F., Fan, Y., Zhang, X., Lin, W., & Wu, X. (2021). Dapagliflozin, metformin, monotherapy or both in patients with metabolic syndrome. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-03773-z
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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