Dapavel 5 Mg Tablet 10

Dapavel 5 Tablet 10

Intas Pharmaceuticals Ltd

Strip of 10 Units

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Composition

Dapagliflozin (5 Mg)

Strength:

5 MG 10 MG

Dapavel 5 Tablet is commonly used to manage type 2 diabetes mellitus, a condition that affects your body's ability to use sugar. It belongs to a group of medicines known as sodium-glucose co-transporter 2 (SGLT2) inhibitors.

In addition to helping control blood sugar levels, the medicine is also used to reduce the risk of hospitalisations related to heart failure and delay the progression of kidney disease in certain patients. These additional uses make it a versatile tool for managing some complications associated with type 2 diabetes.

Before you start taking this medicine, it's crucial that you consult your doctor for the correct dosage and frequency. Inform your doctor about any other medicines you're currently taking or any pre-existing conditions you have. If you notice any new or unusual symptoms while taking this medicine, let your doctor know straight away. To get the most benefit from this medicine, continue taking it for the full duration prescribed by your doctor.

Dapavel 5 Tablet is used for the following:

Improving blood sugar control in adults with type 2 diabetes mellitus, alongside diet and exercise
Lowering the risk of hospitalisation due to heart failure in adults with type 2 diabetes and existing heart disease or multiple risk factors
Slowing down the decline in kidney function, reducing the risk of end-stage kidney disease, preventing cardiovascular death, and lowering chances of hospitalisation for heart failure in adults with chronic kidney disease at risk of progression.

Directions for Use of Dapavel 5 Tablet 10

Here are some general directions for taking Dapavel 5 Tablet:

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Dapavel 5 Tablet is taken orally.

Dapavel 5 Tablet may cause the following common side effects:

Genital mycotic infections: These are yeast infections that occur in the genital area.
Nasopharyngitis: This is inflammation of the nose and throat, which can cause symptoms such as a runny nose, sore throat, and cough.
Urinary tract infections
Back pain
Increased urination
Nausea
Influenza

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve by discontinuing the use of Dapavel 5 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Follow the dietary recommendations provided by your doctor.
Increased urination: Seek medical attention and follow your doctor's advice.

Dapavel 5 Tablet contains dapagliflozin (5 mg) and works in your body through the following mechanisms:

Inhibition of SGLT2: Dapagliflozin blocks the function of SGLT2. This protein is usually responsible for absorbing back most of the glucose filtered by your kidneys.
Increased Glucose Excretion: Because SGLT2 is inhibited, less glucose gets reabsorbed back into your blood from the kidneys. Instead, more glucose gets removed from your body through urine.
Reduced Blood Glucose Levels: As more glucose leaves your body via urine and less gets reabsorbed back into your blood, overall blood glucose levels decrease.

This way, Dapavel 5 Tablet helps manage high blood sugar levels in people with type 2 diabetes mellitus.

Pregnancy

Dapavel 5 Tablet is not recommended during pregnancy. If you are pregnant or planning to conceive, discuss this with your doctor before starting this medicine.

Breastfeeding

It's best to consult your doctor before taking this medicine if you are breastfeeding.

Alcohol

There is no known interaction between alcohol and Dapavel 5 Tablet. However, it's always a good idea to discuss your alcohol consumption with your doctor before starting any new medication.

Liver

Caution is advised while taking Dapavel 5 Tablet if you have liver problems, as this medicine may affect liver function. Discuss with your doctor about any liver-related concerns before starting this medication.

Kidney

Dapavel 5 Tablet should be used with caution if you have kidney problems. As this medicine works by increasing glucose excretion in the urine, it's recommended that you consult your doctor before using it if you have any kidney health issues.

Using Machines & Driving

There is no effect of Dapavel 5 Tablet on the ability to drive or operate machinery. However, if you experience dizziness or tiredness after taking this medicine, avoid driving or using heavy machinery until these symptoms subside.

Allergy

Dapavel 5 Tablet is contraindicated for patients who have a history of serious allergic reactions to dapagliflozin, the active ingredient in this medication. Always inform your doctor about any known allergies before starting this medicine.

Children

Caution is advised while giving Dapavel 5 Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Dapavel 5 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Diuretics (Water Pills): Diuretics like furosemide and hydrochlorothiazide can increase the risk of dehydration and low blood pressure when taken with dapagliflozin.
Insulin and Insulin Secretagogues (Antidiabetics): Medications like insulin and sulfonylureas (e.g., glimepiride) can increase the risk of hypoglycemia when combined with dapagliflozin.
ACE Inhibitors (Blood Pressure Medications): ACE inhibitors such as lisinopril and enalapril may enhance the risk of hyperkalemia (high potassium levels) when used with dapagliflozin.
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): NSAIDs like ibuprofen and naproxen can potentially worsen kidney function when taken with dapagliflozin, especially in patients with pre-existing kidney issues

Drug-Food Interactions

Dapavel 5 Tablet doesn't have any known interactions with food. You can take it without worrying about what you're eating.

Drug-Disease Interactions

Dapavel 5 Tablet interacts with the following diseases:

Kidney Disease: If you have kidney disease, especially if your estimated Glomerular Filtration Rate (eGFR, a measure of kidney function) is less, Dapavel 5 Tablet might not work effectively in controlling your blood sugar levels.
Type 1 Diabetes Mellitus: Dapavel 5 Tablet is not recommended for patients with this type of diabetes as it's not effective in managing their blood glucose levels.
Polycystic Kidney Disease: If you have this condition, you should avoid taking Dapavel 5 Tablet as it may not be safe for you due to its effect on kidney function.

Daily Dose

The dosage of Dapavel 5 Tablet is determined by your doctor, based on factors like the severity of your condition and how you respond to the medicine. Make sure you follow the prescribed dosage and don't exceed it without consulting your doctor.

Over Dose

In case of an overdose, you may experience symptoms like increased urination or nausea. Don't panic, but do inform your doctor about it. It's important not to exceed the prescribed dose to avoid these symptoms.

Missed Dose

If you forget to take your dose of Dapavel 5 Tablet, take it as soon as you remember. However, if it's close to the time for your next dose, just skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store Dapavel 5 Tablet at room temperature, specifically between 20°C and 25°C.
Avoid exposing the medicine to excess heat or moisture; keep it in its original container.
Ensure it is out of reach and sight of children.
Always check the expiry date and do not use it beyond that.

If you are taking Dapavel 5 Tablet for type 2 diabetes, aim to maintain a balanced diet low in simple sugars and high in fibre. This can help manage your blood glucose levels effectively.
Regular physical activity, such as walking or cycling, can also support your body's response to insulin and help manage your diabetes. Always consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	SGLT2 Inhibitor
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes, Heart Failure Risk, Chronic Kidney Disease.

What is the main function of Dapavel 5 Tablet?

Dapavel 5 Tablet helps manage type 2 diabetes by increasing the excretion of sugar in your urine, thus reducing blood sugar levels.

Can Dapavel 5 Tablet be used for type 1 diabetes?

No, Dapavel 5 Tablet is not recommended for managing type 1 diabetes. It's tailored specifically for individuals with type 2 diabetes.

Is Dapavel 5 Tablet safe to take during pregnancy?

No, it's best to avoid Dapavel 5 Tablet during pregnancy due to potential risks to the unborn baby. Always consult your doctor.

How does Dapavel 5 Tablet work in my body?

It contains dapagliflozin which blocks a protein in your kidneys, resulting in more sugar being removed from your body through urine.

What should I do if I have symptoms of a urinary tract infection while using Dapavel 5 Tablet?

If you experience symptoms of urinary tract infection, seek medical help immediately. Your doctor may prescribe appropriate medication to manage the infection.

Can I use Dapavel 5 Tablet if I have kidney disease?

If your kidney function is severely impaired or you have certain types of kidney disease, it's not advised to take Dapavel 5 Tablet.

Does Dapavel 5 Tablet interact with other medicines?

Yes, certain medicines can interact with it and may lead to hypoglycaemia (low blood sugar). Always inform your doctor about all medications you are taking.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India

Country of origin: INDIA

References

AstraZeneca. (2014). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
Dapagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06292
DailyMed - DAPAGLIFLOZIN tablet, film coated. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3aba33aa-f8c6-4b10-85c8-dfa14578d07c
Dapagliflozin: MedlinePlus Drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a614015.html

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