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CompositionDiziron D Tablet is used in the management of symptoms related to inner ear balance disorders, specifically motion sickness, vertigo, and Ménière's disease. This combination medicine contains an antihistamine (Cinnarizine) and a calcium channel blocker (Dimenhydrinate or a similar agent). It works by stabilizing the inner ear's fluid balance and reducing the hyperactivity that causes vertigo, nausea, vomiting, and dizziness, thereby improving equilibrium.
Diziron D Tablet is used for managing symptoms of inner ear disorders, primarily addressing vertigo (such as nausea, vomiting, and dizziness), and is also effective in preventing and managing motion sickness. It helps control symptoms associated with Ménière's disease.
Here's how you should take Diziron D Tablet:
Swallow the tablet whole with a glass of water. Don't crush or chew it.
Take the tablet preferably with meals to avoid stomach upset.
In case you are taking this medicine to prevent motion sickness, take one tablet 30 minutes before your journey begins.
Always adhere to your doctor's prescribed dosage and schedule. If in doubt, consult your doctor.
Diziron D Tablet is taken orally.
Diziron D Tablet may cause drowsiness, dry mouth, headache, gastrointestinal disturbances like nausea or indigestion, and weight gain.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Diziron D Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
In terms of managing less severe side effects:
Drowsiness: Consider taking this medicine at night to lessen daytime drowsiness.
Gastrointestinal disturbances: Try taking the tablet with meals to reduce stomach discomfort.
Diziron D Tablet comprises two active ingredients which work together to manage symptoms of motion sickness and vertigo:
Cinnarizine (20 mg): As a calcium channel blocker, cinnarizine acts on the inner ear by reducing vasoconstriction. This means it prevents blood vessels from narrowing, thereby improving microcirculation and reducing pressure within the inner ear. Additionally, cinnarizine blocks H1 receptors, exhibiting antihistaminic properties.
Dimenhydrinate (40 mg): This ingredient works as an antihistamine and anticholinergic agent. Essentially, it suppresses activity in the vestibular system – a part of the inner ear that helps maintain balance – thereby reducing vertigo and nausea. Dimenhydrinate also inhibits the chemoreceptor trigger zone, an area in your brain that controls vomiting.
Caution is advised while taking Diziron D Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.
If you are a breastfeeding mother, use Diziron D Tablet with caution. Please consult your doctor before using this medicine.
Avoid alcohol consumption while taking Diziron D Tablet, as it may increase the risk of drowsiness.
If you have liver problems, please discuss them with your doctor before starting Diziron D Tablet. This medicine may affect liver function.
If you have a history of kidney problems, it would be wise to consult your doctor before taking Diziron D Tablet.
Diziron D Tablet can cause drowsiness and sedation. Avoid driving or operating heavy machinery after taking this medicine.
If you have any known allergies to cinnarizine or dimenhydrinate, do not take Diziron D Tablet.
Diziron D Tablet should not be given to children under 12 years of age unless prescribed by a doctor. Always consult your doctor before giving any medicine to a child.
Older patients should take Diziron D Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.
Diziron D Tablet interacts with the following medicines:
Central Nervous System (CNS) Depressants: Sedatives like diazepam and tranquilizers such as lorazepam may interact with Diziron D Tablet, potentially increasing drowsiness and sedation.
Anticholinergic Agents: Antiparkinsonian medicines like benztropine and tricyclic antidepressants such as amitriptyline can interact with this medicine, enhancing anticholinergic effects like dry mouth and constipation.
Anti-epileptic Medications: Medicines like phenytoin or carbamazepine can interact with Diziron D Tablet, potentially altering their effectiveness in controlling seizures.
Grapefruit juice can increase the absorption of cinnarizine in your body, possibly leading to enhanced side effects.
Diziron D Tablet interacts with the following diseases:
Glaucoma: This medicine can cause an increase in intraocular pressure, worsening symptoms of glaucoma.
Prostate Hyperplasia: Patients with an enlarged prostate may experience difficulty in urinating due to the anticholinergic effects of this medicine.
Urinary Retention: This medicine may exacerbate urinary retention issues. It's advisable to consult your doctor if you have a history of urinary retention before starting this medication.
The daily dose of Diziron D Tablet should be taken as instructed by your doctor. The dosage may vary based on factors such as the severity of your symptoms and response to the medication. Always follow your doctor's prescribed dosage and never exceed it without consulting your doctor.
If you accidentally take more than the recommended dose of Diziron D Tablet, you may experience common side effects like drowsiness, dry mouth and headache in a more intense form. Should this occur, inform your doctor about the extra tablets taken.
If you forget to take your regular dose of Diziron D Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the one you missed and go back to your normal schedule. Never double up on doses without consulting your doctor.
Store Diziron D Tablet at a steady room temperature between 15-30°C.
The Tablet should be kept in its original packaging to shield it from moisture and direct sunlight.
Always keep this medicine out of reach of children.
To ensure efficacy, consume the medicine before its expiry date.
Since Diziron D Tablet is used to manage vertigo and motion sickness, remember to avoid excessive intake of caffeine as it can exacerbate dizziness.
Any activities like yoga or tai chi that can aid in improving balance might help manage symptoms of vertigo. Please consult your doctor before starting any exercise routine.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Motion Sickness, Vertigo, Ménière's Disease |
| Drug Category | Calcium Channel Blocker, Antihistaminic |
| Therapeutic Category | Antiemetic, Antivertigo |
Diziron D Tablet is used to manage motion sickness, vertigo, and inner ear balance disorders like Ménière's disease.
It contains cinnarizine and dimenhydrinate. These compounds work together to reduce symptoms of motion sickness and vertigo.
It is recommended to take this medicine with meals to lessen possible stomach upset.
Take the missed dose as soon as you remember. However, if it's nearly time for the next dose, skip the missed one.
Please consult your doctor before taking this medicine if you're pregnant or breastfeeding.
It's advisable to avoid alcohol as it might increase drowsiness, a common side effect of this medicine.
Store it at room temperature (15-30°C), away from moisture and sunlight, and out of children's reach.
Check out Editorial Policy
Southern Cross Pharma Pty Ltd. (2019). Product AUSPAR CIZIGO/CIZINATE/CIZERE Cinnarizine/Dimenhydrinate Southern Cross Pharma Pty Ltd PM 2017-00806-1-1 FINAL 12 November 2019. https://www.tga.gov.au/sites/default/files/auspar-cinnarizine-dimenhydrinate-191112-pi.pdf
NPS MedicineWise. (2021). Cinnarizine/dimenhydrinate [Commentary]. Australian Prescriber, 44–44(2), 62–63. https://www.nps.org.au/assets/AP/pdf/p62-Cinnarizinedimenhydrinate.pdf
Scholtz, A., Ilgner, J., Loader, B., Pritschow, B. W., & Weisshaar, G. (2015). Cinnarizine and dimenhydrinate in the treatment of vertigo in medical practice. Wiener Klinische Wochenschrift, 128(9–10), 341–347. https://doi.org/10.1007/s00508-015-0905-5
Efficacy and Safety of a Fixed Combination of Cinnarizine 20 mg and Dimenhydrinate 40 mg vs Betahistine Dihydrochloride 16 mg in Patients with Peripheral Vestibular Vertigo: A Prospective, Multinational, Multicenter, Double-Blind, Randomized, Non-inferiority Clinical Trial. (n.d.). springermedizin.de. https://www.springermedizin.de/efficacy-and-safety-of-a-fixed-combination-of-cinnarizine-20-mg-/24113622
Cinnarizine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00568
Dimenhydrinate: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00985
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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