Eptus 50 Mg Tablet 10

Eptus 50 Tablet 10

Glenmark Pharmaceuticals Ltd.

Strip of 10 Units

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MRP ~~₹665.5~~

₹545.71

₹66.55/Units

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Composition

Eplerenone (50 Mg)

Strength:

50 MG 10 MG

Eptus 50 Tablet is primarily used to manage high blood pressure, commonly known as hypertension. This medicine falls under the category of mineralocorticoid receptor antagonists which has a significant role in managing blood pressure conditions.

Apart from hypertension, this medicine is also used in the management of heart failure. Specifically, it's effective in patients who've had a heart attack and are now dealing with stable symptomatic heart failure. By reducing cardiovascular mortality and hospitalization risks, it aids in enhancing patient survival.

Remember, it's crucial to follow your doctor's instructions while taking this medicine. Inform your doctor about any other existing medical conditions or ongoing medications you might have before starting this medicine. If you experience any side effects, notify your doctor immediately. Also, make sure you continue with the medication for the entire duration suggested by your doctor for optimal results.

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Eptus 50 Tablet is typically used for the following purposes:

Managing high blood pressure
Assisting in heart failure management post-heart attack

Directions for Use of Eptus 50 Tablet 10

Here are some simple steps to follow when taking Eptus 50 Tablet:

Swallow the tablet whole with a glass of water.
Do not chew or crush the tablet.
It's crucial not to exceed the recommended dose without consulting your doctor.
It's equally important not to stop taking this medication abruptly without speaking to your doctor first.

Eptus 50 Tablet is taken orally.

While taking Eptus 50 Tablet, you may experience the following side effects:

Dizziness
Headache
Fatigue
Hypertriglyceridaemia: This is an increase in the level of triglycerides in your blood, which are a type of fat.
Hyperglycaemia: This refers to high blood sugar levels.
Hyperuricaemia: This condition involves having excess uric acid in your blood.
Hyponatraemia: This means you have low sodium levels in your blood.
Gastrointestinal disturbances such as diarrhoea, nausea, and abdominal pain.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Eptus 50 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Fatigue: Consider taking Eptus 50 Tablet at night if it causes you fatigue during the day.
Gastrointestinal disturbances: If you experience diarrhoea, nausea or abdominal pain, try taking Eptus 50 Tablet with food.

Eptus 50 Tablet contains Eplerenone (50 mg) and works on your body in the following ways:

Mineralocorticoid Receptor Blockage: Eplerenone selectively blocks the mineralocorticoid receptor (MR) in your body. This receptor is the key binding site for aldosterone, a hormone responsible for maintaining water and salt balance in your body.
Increased Diuresis: By blocking the effects of aldosterone, Eplerenone causes an increase in the excretion of sodium and water through urine, a process called diuresis. Simultaneously, it retains potassium, which is essential for normal body function.
Reduction of Blood Pressure: The combined action of sodium and water excretion, along with potassium retention, leads to reduced blood volume and blood pressure. This ultimately takes off the extra strain on your heart.

Pregnancy

If you are pregnant or planning to conceive, caution is advised while taking Eptus 50 Tablet. Consult your doctor before starting this medicine.

Breastfeeding

Caution is recommended while taking Eptus 50 Tablet if you are breastfeeding. It's best to discuss this with your doctor before starting the medication.

Alcohol

Avoid consuming alcohol while on Eptus 50 Tablet as it can intensify some side effects. It's advisable to consult your doctor about safe alcohol use.

Liver

Eptus 50 Tablet is often prescribed for patients who may have liver health concerns. It's recommended to discuss this with your doctor before beginning this medication.

Kidney

If you have a history of kidney problems, caution is advised before using Eptus 50 Tablet. It is a good idea to consult your doctor before beginning this medicine.

Using Machines & Driving

Eptus 50 Tablet may cause dizziness. Caution is advised when driving or operating machinery until you know how the medicine impacts you.

Allergy

If you are allergic to eplerenone or any other ingredients of Eptus 50 Tablet, do not take the medicine. Inform your doctor about any known allergies.

Children

Caution is advised while giving Eptus 50 Tablet to children under 18. Always consult your doctor before administering any medicine to a child.

Older Patients

Older patients should take Eptus 50 Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Eptus 50 Tablet interacts with the following medicines:

Strong CYP3A4 inhibitors: Medicines such as ketoconazole, itraconazole, and clarithromycin can potentially increase eplerenone levels in your body, increasing your risk of high potassium levels (hyperkalaemia).
Potassium-sparing diuretics: Co-administration of these medications with Eptus 50 Tablet can also lead to hyperkalaemia.
NSAIDs: When taken together with Eptus 50 Tablet, NSAIDs could further increase your risk of hyperkalaemia.
ACE inhibitors and ARBs: These medicines can also raise potassium levels when used alongside Eptus 50 Tablet.
Cardiac glycosides: Eptus 50 Tablet may enhance the concentration of medicines like digoxin in your blood.

Drug-Food Interactions

Certain foods can interact with Eptus 50 Tablet:

High-potassium foods: Consuming foods rich in potassium while taking Eptus 50 Tablet may increase your risk of hyperkalaemia.

Drug-Disease Interactions

Eptus 50 Tablet interacts with the following diseases:

Impaired renal function: In patients with kidney issues, using Eptus 50 Tablet can increase the risk of hyperkalaemia.
Diabetes: Diabetic patients taking Eptus 50 Tablet should closely monitor their potassium levels due to a higher risk of hyperkalaemia.
Hyperkalaemia: Individuals with high potassium levels should avoid taking Eptus 50 Tablet as it might exacerbate their condition.

Daily Dose

Your doctor will prescribe the daily dose of Eptus 50 Tablet. This may vary depending on factors like your condition's severity and how you respond to the medicine. Ensure you follow the prescribed dosage without exceeding it and always consult your doctor for any changes.

Over Dose

If you accidentally consume more than the prescribed dose of Eptus 50 Tablet, you might experience common overdose symptoms such as dizziness or fatigue. In such cases, it's advisable to inform your doctor.

Missed Dose

Should you forget to take your Eptus 50 Tablet, take it as soon as you remember. If it's nearly time for the next dose, skip the missed one and continue with your regular schedule. Do not increase your dosage without consulting your doctor.

Always store your Eptus 50 Tablet in its original packaging.
Keep the medicine away from direct light and moisture.
Place the medicine safely out of the reach of children.
Remember to use your Eptus 50 Tablet before its expiry date.

Try to maintain a diet low in salt. This helps manage high blood pressure, which Eptus 50 Tablet is designed to help regulate.
Engage in regular, doctor-advised physical activity. Physical exercise can support heart health, which is particularly beneficial if you're taking Eptus 50 Tablet for heart failure.

Fact Box

Drug Category	Mineralocorticoid Receptor Antagonist
Therapeutic Category	Diuretic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Tablet for heart failure.

What is Eptus 50 Tablet used for?

Eptus 50 Tablet is primarily used to manage hypertension (high blood pressure) and heart failure symptoms after a heart attack.

How does Eptus 50 Tablet work?

This medicine works by blocking a hormone in your body called aldosterone. This hormone reduces water and sodium retention, which in turn lowers blood pressure.

How soon can I expect results from Eptus 50 Tablet?

The medicine starts working within a few days, but it may take several weeks for full effects on your blood pressure to be noticeable.

Can I stop taking Eptus 50 Tablet suddenly?

Abrupt discontinuation of this medication isn't recommended due to potential rebound effects. Always consult your doctor before making changes to your medication schedule.

Can I take Eptus 50 Tablet with food?

Yes, Eptus 50 Tablet can be taken with or without food. However, it should be swallowed whole with water for best results.

What should I do if I miss a dose of Eptus 50 Tablet?

If you miss a dose, take it as soon as you remember. Do not double the dose if it's almost time for the next one.

Is long-term use of Eptus 50 Tablet safe?

Long-term use of Eptus 50 Tablet is generally safe when taken as directed, but regular monitoring of serum potassium and kidney function is important.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

Glenmark House, HDO-Corporate Building, Wing-A, B.D. Sawant Marg, Chakala Off. Western Express Highway, Andheri (East), Mumbai, Maharashtra, 400099 India

Country of origin: INDIA

References

U.S. Food and Drug Administration. (2002). Eplerenone Tablets Label. Retrieved 1 April 2024 from https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/21437lbl.pdf
Eplerenone: MedlinePlus drug information. (2024, July 20). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a603004.html
Eplerenone. (2024, October 21). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB00700
PubChem. (n.d.). Eplerenone. National Center for Biotechnology Information. https://pubchem.ncbi.nlm.nih.gov/compound/Eplerenone#section=Drug-Indication
Pfizer. (2016). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021437s013lbl.pdf

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