Gliclaglaze Met 60500 Mg Tablet Sr 15

Gliclaglaze Met 60/500 MG Tablet Sr 15

Steris Healthcare

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STRIP of 15 Units

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Composition

Gliclazide (60 Mg) + Metformin (500 Mg)

Gliclaglaze Met 60/500 MG Tablet Sr 15 is primarily used to manage type 2 diabetes mellitus in adults. This combination formulation belongs to the class of oral antidiabetic medications.

In addition to its main use, it also helps reduce the risk of complications associated with diabetes, such as heart disease, kidney damage, and nerve problems often linked with uncontrolled blood sugar levels.

Consult your doctor for the correct dosage and frequency based on your health. Before starting this medication, inform your doctor about any pre-existing conditions or other ongoing medications. If you experience any side effects while using this medicine, notify your doctor immediately. To achieve the best results, continue taking the medicine for the full duration prescribed by your doctor.

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Uses of Gliclaglaze Met 60/500 MG Tablet Sr 15

Gliclaglaze Met 60/500 MG Tablet Sr 15 is used for the management of Type 2 diabetes mellitus.

Directions for Use of Gliclaglaze Met 60/500 MG Tablet Sr 15

The tablet should be taken whole.
Do not chew, crush, or break the tablet.
Always follow your doctor's instructions regarding dosage and duration.

Gliclaglaze Met 60/500 MG Tablet Sr 15 is taken orally.

Side Effects of Gliclaglaze Met 60/500 MG Tablet Sr 15

You may experience the following common side effects while taking Gliclaglaze Met 60/500 MG Tablet Sr 15:

Nausea
Vomiting
Diarrhoea
Abdominal pain
Dizziness
Skin rash
Hypoglycaemia: This is when your blood sugar levels drop below normal.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Gliclaglaze Met 60/500 MG Tablet Sr 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here's how you might manage a couple of common side effects:

Nausea: Try taking Gliclaglaze Met 60/500 MG Tablet Sr 15 with a meal to help reduce feelings of nausea.
Hypoglycaemia: If you experience hypoglycaemia symptoms after taking this medicine, consider taking it after meals.

How Gliclaglaze Met 60/500 MG Tablet Sr 15 Works?

Gliclaglaze Met 60/500 MG Tablet Sr 15 contains two active ingredients:

Metformin (500 mg): As a biguanide, metformin lowers blood glucose levels by decreasing glucose production in the liver, reducing intestinal glucose absorption, and improving insulin sensitivity in peripheral tissues. Essentially, it helps lower your blood sugar by enhancing your body's response to insulin and reducing glucose production in the liver.
Gliclazide (60 mg): As a sulfonylurea, gliclazide stimulates insulin secretion from pancreatic beta cells. It works by interacting with a receptor on the beta cell membrane, initiating a series of events that increase insulin release. In simpler terms, it helps your body produce more insulin.

Pregnancy

Caution is advised while taking Gliclaglaze Met 60/500 MG Tablet Sr 15 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, be sure to discuss taking Gliclaglaze Met 60/500 MG Tablet Sr 15 with your doctor. They can guide you through the potential risks and benefits.

Alcohol

Drinking alcohol might increase the risk of low blood sugar (hypoglycaemia) and lactic acidosis. You should avoid consuming alcohol while taking Gliclaglaze Met 60/500 MG Tablet Sr 15. Discuss your alcohol consumption with your doctor.

Liver

If you have liver health issues, talk to your doctor before starting Gliclaglaze Met 60/500 MG Tablet Sr 15. They will assess whether this medicine is suitable for you based on your liver's condition.

Kidney

Gliclaglaze Met 60/500 MG Tablet Sr 15 should be used with caution if you have a history of kidney problems. Always consult your doctor before taking this medicine in such cases.

Using Machines & Driving

If Gliclaglaze Met 60/500 MG Tablet Sr 15 makes you feel dizzy or unwell, avoid driving or using heavy machines.

Allergy

If you're allergic to metformin, gliclazide, or any other ingredients in Gliclaglaze Met 60/500 MG Tablet Sr 15, do not take this medicine. Talk to your doctor about other options available.

Children

Gliclaglaze Met 60/500 MG Tablet Sr 15 is not recommended for individuals under 18 years of age. Always consult your doctor before administering any medication to a child.

Older Patients

Older patients should take Gliclaglaze Met 60/500 MG Tablet Sr 15 under medical supervision, as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Interactions of Gliclaglaze Met 60/500 MG Tablet Sr 15

Drug-Drug Interactions

Gliclaglaze Met 60/500 MG Tablet Sr 15 interacts with the following medicines:

Beta-blockers: Medicines like propranolol and atenolol may enhance the blood sugar-lowering effect of Gliclaglaze Met 60/500 MG Tablet Sr 15, increasing the risk of hypoglycaemia (low blood sugar).
ACE inhibitors: Medicines such as ramipril or lisinopril can also enhance the glycaemic control of Gliclaglaze Met 60/500 MG Tablet Sr 15, potentially leading to hypoglycaemia.
Thiazide diuretics: Medications like hydrochlorothiazide may decrease the blood sugar-lowering effect of Gliclaglaze Met 60/500 MG Tablet Sr 15.
Corticosteroids: Medicines like prednisone and dexamethasone might reduce the hypoglycaemic effect of Gliclaglaze Met 60/500 MG Tablet Sr 15.
Thyroid hormones: Levothyroxine may lessen the effectiveness of Gliclaglaze Met 60/500 MG Tablet Sr 15in controlling blood sugar levels.
Cationic medications: Medicines like amiloride, digoxin, and ranitidine can interact with the metformin component of Gliclaglaze Met 60/500 MG Tablet Sr 15, potentially decreasing its elimination from the body.

Drug-Food Interactions

Certain food items may interact with Gliclaglaze Met 60/500 MG Tablet Sr 15:

High-fat meals: These can slow down the absorption of Gliclaglaze Met 60/500 MG Tablet Sr 15, making it less effective in controlling your blood sugar levels.

Drug-Disease Interactions

Gliclaglaze Met 60/500 MG Tablet Sr 15 interacts with the following diseases:

Renal impairment: As metformin is primarily excreted by the kidneys, those with kidney disease should be cautious when using Gliclaglaze Met 60/500 MG Tablet Sr 15.
Hepatic impairment: Patients with liver disease should use this medicine with care, as its effectiveness may be affected.
Type 1 diabetes mellitus and diabetic ketoacidosis: Gliclaglaze Met 60/500 MG Tablet Sr 15 is not recommended for these conditions.

Daily Dose

Your doctor will determine the daily dosage of Gliclaglaze Met 60/500 MG Tablet Sr 15 based on your individual needs. It's crucial to adhere to this dosage and not exceed it without your doctor's advice.

Over Dose

If you accidentally take more than the prescribed dose of Gliclaglaze Met 60/500 MG Tablet Sr 15, you may experience symptoms such as nausea, stomach discomfort, or dizziness. If these symptoms persist or worsen, contact your doctor right away.

Missed Dose

In case you forget to take a dose of Gliclaglaze Met 60/500 MG Tablet Sr 15, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not increase your dosage without consulting your doctor.

Store Gliclaglaze Met 60/500 MG Tablet Sr 15 in a dry place below 30°C.
Protect from direct light and moisture.
Keep out of reach of children.

Incorporate moderate exercise like brisk walking or cycling into your routine. This can help manage blood sugar levels.
Aim to eat a balanced diet with plenty of whole grains, fruits, vegetables, and lean proteins. Limit your intake of sugary foods and drinks, as these can cause spikes in blood sugar levels.

Fact Box

Drug Category	Sulfonylurea, Biguanide
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is Gliclaglaze Met 60/500 MG Tablet Sr 15 used for?

It is used to manage type 2 diabetes in adults when diet, exercise, and single-agent therapy fail to control blood sugar levels.

How does Gliclaglaze Met 60/500 MG Tablet Sr 15 work?

It contains metformin and gliclazide. Metformin reduces blood glucose levels, and gliclazide stimulates insulin secretion from the pancreas.

Can I take this medicine if I have type 1 diabetes?

No, Gliclaglaze Met 60/500 MG Tablet Sr 15is not suitable for people with type 1 diabetes. It's designed for managing type 2 diabetes.

How should I take my Gliclaglaze Met 60/500 MG Tablet Sr 15?

You should swallow the tablet whole. Do not crush, chew, or split it.

What might happen if I miss a dose of Gliclaglaze Met 60/500 MG Tablet Sr 15?

If you miss a dose, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one.

Can Gliclaglaze Met 60/500 MG Tablet Sr 15cause low blood sugar levels?

Yes, one of its ingredients, gliclazide, can cause low blood sugar or hypoglycaemia. Be aware of its symptoms and how to manage it. Consult your doctor for more guidance.

Is it safe to drink alcohol while taking Gliclaglaze Met 60/500 MG Tablet Sr 15?

No, alcohol can increase the risk of hypoglycaemia and lactic acidosis. Therefore, avoid alcohol consumption while taking this medication.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Betina Chandolia

Medical Content Manager | 10 years

BDS, MDS, PGCCL, PGDMH

Check out Editorial Policy

Manufacturer details

Tanaji Chowk, Ambedkar Nagar, Kurla West, Kurla, Mumbai, Maharashtra 400070

Country of origin: INDIA

References

Metformin: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a696005.html
Campbell DB, Lavielle R, Nathan C. The mode of action and clinical pharmacology of gliclazide: a review. Diabetes Res Clin Pract. 1991;14 Suppl 2:S21-36. https://pubmed.ncbi.nlm.nih.gov/1794262/
About gliclazide. (2022, April 1). NHS. https://www.nhs.uk/medicines/gliclazide/about-gliclazide/
FDA. (n.d.). GLUMETZA™ (metformin hydrochloride extended release tablets) Tablets. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021748s002lbl.pdf
Gliclazide. (2024). Diabetes UK. https://www.diabetes.org.uk/guide-to-diabetes/managing-your-diabetes/treating-your-diabetes/tablets-and-medication/sulphonylureas/gliclazide

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