Gp 0.5 Tablet 10

Usv Pvt Ltd

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Composition

Glimepiride (0.5 Mg)

Strength:

1 MG 2 MG 3 MG 0.5 MG 4 MG

GP-0.5 Tablet is a medicine primarily used to manage type 2 diabetes mellitus in adults. This oral medication falls under the category of sulfonylurea class of antidiabetic medicines.

It is used as an adjunct to diet and exercise to enhance glycemic control. By lowering blood glucose levels, it helps prevent severe complications associated with diabetes, such as kidney damage, blindness, nerve issues, and sexual dysfunction.

This medicine should be taken orally as advised by your doctor. It's crucial that you inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while taking this medicine, notify your doctor immediately. Continue taking the tablet for the duration prescribed by your doctor to achieve optimal results.

GP-0.5 Tablet is used for the following:

Improving blood sugar control in adults with type 2 diabetes mellitus
Lowering blood glucose levels to prevent serious diabetes complications like kidney damage
Reducing the risk of blindness, a common issue caused by uncontrolled diabetes
Preventing nerve problems that can lead to limb amputations
Helping deter sexual dysfunction issues linked with high blood sugar levels

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

GP-0.5 Tablet is taken orally.

GP-0.5 Tablet may have the following side effects:

Hypoglycaemia: This is a condition where your blood sugar levels drop too low.
Nausea
Headache
Dizziness
Weakness
Weight gain

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of GP-0.5 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Hypoglycaemia: If you feel shaky or faint, eat something sweet like a piece of fruit or a biscuit.
Nausea: Try taking GP-0.5 Tablet with or after light meals to reduce feelings of nausea.

GP-0.5 Tablet contains glimepiride (0.5 mg), which influences the body in the following ways:

Stimulates Insulin Secretion: Glimepiride works by binding to sulfonylurea receptors on pancreatic beta cells, making them more sensitive to glucose and thus increasing insulin release.
Reduces Blood Sugar Levels: The enhanced insulin release resulting from the action of glimepiride effectively reduces blood sugar levels.
Lowers Glucose Output: Apart from its primary function, glimepiride also has some peripheral effects, including lowering glucose output from the liver.

Pregnancy

GP-0.5 Tablet is not recommended during pregnancy. If you are pregnant or planning a baby, it's crucial to discuss this with your doctor before starting this medicine.

Breastfeeding

GP-0.5 Tablet is not recommended for breastfeeding women. Consult your doctor to understand potential risks and benefits.

Alcohol

Avoid consuming alcohol while taking GP-0.5 Tablet, as it might increase the risk of low blood sugar levels (hypoglycemia).

Liver

Caution is advised while taking GP-0.5 Tablet if you have mild to moderate liver impairment. It's not recommended if you have severe liver diseases. Discuss any liver problems with your doctor before starting this medicine, as it could affect liver function.

Kidney

Caution is advised when using GP-0.5 Tablet if you have a history of kidney problems. It's best to consult your doctor before taking this medicine.

Using Machines & Driving

As GP-0.5 Tablet may cause dizziness, be cautious when driving or operating machinery until you know how this medicine affects you.

Allergy

GP-0.5 Tablet should not be taken if you are allergic to glimepiride or any other sulfonylureas. Always inform your doctor about any allergies before starting this medicine.

Children

GP-0.5 Tablet is not recommended for use in children. It's advisable to consult your doctor for other safer options.

Older Patients

Elderly patients should take GP-0.5 Tablet under medical supervision as they may be more susceptible to its side effects, including low blood sugar levels (hypoglycemia). Caution is advised if patients are above 70 years of age due to potential liver and kidney issues. Your doctor will guide you based on your health status.

Drug-Drug Interactions

GP-0.5 Tablet interacts with the following medicines:

Insulin and other antidiabetic medicines: Medicines like insulin or metformin combined with GP-0.5 Tablet can increase the risk of low blood sugar levels (hypoglycaemia).
ACE inhibitors: Medicines such as enalapril or lisinopril taken with GP-0.5 The concomitant use of this tablet with antihypertensives can increase the risk of lactic acidosis.
Calcium Channel Blockers: Medicines like amlodipine or nifedipine may reduce the effectiveness of GP-0.5 Tablet in controlling blood glucose.

Drug-Food Interactions

No specific drug-food interactions have been established for GP-0.5 Tablet.

Drug-Disease Interactions

GP-0.5 Tablet interacts with the following diseases:

Kidney disease: Patients with kidney disease should use GP-0.5 Tablet cautiously as it could increase the risk of hypoglycaemia.
Liver disease: Patients with liver disease need careful monitoring as GP-0.5 Tablet could lead to altered medicine effects.
Thyroid disorders: Thyroid conditions might affect how your body responds to GP-0.5 Tablet, requiring regular blood sugar monitoring.

Daily Dose

The daily recommended dose of GP-0.5 Tablet should be taken as directed by your doctor. It's important to remember that doses may vary based on individual factors such as the severity of the condition and how well you're responding to the medicine. Always follow your doctor's instructions and never exceed the prescribed dosage without consulting them.

Over Dose

If you accidentally take more than your prescribed dose of GP-0.5 Tablet, you may experience common overdose symptoms like nausea, dizziness, and headache. If these symptoms persist or worsen, inform your doctor.

Missed Dose

In case you forget to take your GP-0.5 Tablet at its scheduled time, take it as soon as you remember. However, if it's nearly time for the next dose, skip the missed one and continue with your regular dosing schedule. Never change your dosage without talking to your doctor first.

Keep GP-0.5 Tablet in a cool and dry place, ideally below 30°C.
Protect the medicine from direct light and moisture.
Ensure it is stored out of reach and sight of children to prevent accidental ingestion.
Always check the expiry date on the pack before use; do not use if expired.

Regular physical activity aids in managing your blood glucose levels, so try to include mild exercises, like walking, into your daily routine.
Maintain a balanced diet low in sugar and high in fibre to support the management of type 2 diabetes mellitus.

Fact Box

Drug Category	Insulin Secretagogue
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is GP-0.5 Tablet used for?

GP-0.5 Tablet is used to manage type 2 diabetes mellitus in adults, helping to reduce high blood sugar levels.

How does GP-0.5 Tablet work?

GP-0.5 Tablet works by stimulating the pancreas to release more insulin, which helps lower your blood sugar levels.

Can GP-0.5 Tablet be taken during pregnancy or while breastfeeding?

No, GP-0.5 Tablet should not be taken during pregnancy or while breastfeeding. Always consult your doctor for advice.

What should I do if I miss a dose of GP-0.5 Tablet?

If you miss a dose, take it as soon as you remember unless it's nearly time for the next one.

Can I drink alcohol while taking GP-0.5 Tablet?

You're advised to avoid alcohol when taking this medicine as it can increase the risk of low blood sugar and liver issues.

How long does it take for GP-0.5 Tablet to work?

GP-0.5 Tablet starts working soon after you take it but it may take a few weeks to see the full effects on your blood sugar levels.

What are the signs of low blood sugar caused by GP-0.5 Tablet?

Signs of low blood sugar include sweating, shaking, fast heartbeat, blurred vision, dizziness, headache, and confusion.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

USV Private Limited Arvind Vithal Gandhi Chowk, BSD Marg, Station Road, Govandi East, Mumbai - 400 088. India.

Country of origin: INDIA

References

AMARYL. (n.d.). AMARYL (glimepiride tablets) 1, 2, and 4 mg. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020496s021lbl.pdf
Glimepiride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00222
DailyMed - GLIMEPIRIDE- glimepiride tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=60e9397e-83b9-489e-9683-6f87e458bbaa
Glimepiride: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a696016.html

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