Gutron 25 Mg Tablet 20

Gutron 2.5mg Tablet 20

Cipla Ltd.

Strip of 20 Units

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Composition

Midodrine (2.5 Mg)

Gutron 2.5 mg Tablet is primarily used to manage orthostatic hypotension a condition where your blood pressure significantly drops when you stand up, causing dizziness and potential fainting. This medicine belongs to a class of medications known as sympathomimetic amines.

In addition to managing orthostatic hypotension, this medicine is beneficial for patients with autonomic dysfunction. This includes conditions like Parkinson's disease, multiple system atrophy, and pure autonomic failure, where the body's automatic functions are impaired.

It's crucial to take this medicine as directed by your doctor. Make sure you inform your doctor about any ongoing medications or pre-existing conditions before starting on this medication. If you notice any side effects while on this medicine, let your doctor know immediately. For optimal results, continue taking the medicine for the entire duration prescribed by your doctor.

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Gutron 2.5 mg Tablet is used for the following:

Managing symptomatic orthostatic hypotension: This condition is characterised by a sudden drop in blood pressure when standing up, which can cause dizziness or fainting.
Assisting patients with autonomic dysfunction: These include individuals diagnosed with Parkinson's disease, multiple system atrophy, or pure autonomic failure, where the control of blood pressure is affected.

Directions for Use of Gutron 2.5mg Tablet 20

To ensure you're using Gutron 2.5 mg Tablet correctly, please follow these instructions:

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Gutron 2.5 mg Tablet is taken orally.

Gutron 2.5 mg Tablet may cause the following common side effects:

Itching
Goosebumps: This is a condition where your skin develops tiny bumps, similar to the skin of a goose when its feathers are plucked.
Tingling sensation
Chills
Urinary retention: This is when you have trouble emptying your bladder completely.
Elevated blood pressure while lying down, also known as supine hypertension

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve by discontinuing the use of Gutron 2.5 mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips to manage common side effects:

Itching: Maintain hygiene and avoid all allergens. If there is severe itching, inform your doctor.
Supine hypertension: Seek medical attention immediately.

This medication contains Midodrine (2.5 mg), which works on your body in several ways:

Enzymatic Conversion: Midodrine is converted in the body to an active substance called desglymidodrine through enzymatic hydrolysis.
Alpha-1 Adrenergic Receptor Activation: Desglymidodrine acts as an alpha-1 adrenergic receptor agonist. It attaches to these receptors found on blood vessels in the body.
Vasoconstriction: Once attached to the receptors, it causes the blood vessels to constrict or become narrower.
Blood Pressure Elevation: The narrowing of blood vessels leads to an increase in blood pressure, counteracting the sudden drop in pressure that occurs when you stand up.

Pregnancy

Caution is advised while taking Gutron 2.5 mg Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it's advised to consult with your doctor before starting this medicine.

Alcohol

It's always wise to limit alcohol consumption when on any medication.

Liver

While using Gutron 2.5 mg Tablet, it's advisable to discuss your liver health with your doctor. They will guide you based on your health status.

Kidney

Caution is advised before taking Gutron 2.5 mg Tablet if you have a history of any kidney problems. It's a good idea to consult your doctor before starting this medicine.

Using Machines & Driving

Gutron 2.5 mg Tablet could cause dizziness or blurred vision. Be cautious about engaging in activities requiring mental alertness, such as driving or operating hazardous machinery, until you know how the medicine affects you.

Allergy

If you know that you're allergic to midodrine or any other component of Gutron 2.5 mg Tablet, avoid using this medicine and consult your doctor for alternatives.

Children

Always consult your doctor before giving this medicine to a child as it may not be safe.

Older Patients

Older patients should take Gutron 2.5 mg Tablet under medical supervision as they may be more susceptible to its side effects and might also have liver and kidney issues. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Gutron 2.5 mg Tablet interacts with the following medicines:

Sympathomimetic Agents: Medicines such as phenylephrine, pseudoephedrine, or ephedrine could see their blood pressure-raising effects amplified when taken alongside Gutron 2.5 mg Tablet.
Heart Medications: Digitalis, a heart medication, could interact with Gutron 2.5 mg Tablet and increase the risk of slowed heart rate or bradycardia.
Alpha-adrenergic Blocking Agents: Medicines like prazosin, terazosin and doxazosin might have their effects weakened when used with Gutron 2.5 mg Tablet.
Corticosteroids: Fludrocortisone, a corticosteroid medicine, may enhance the blood pressure-elevating effects of Gutron 2.5 mg Tablet and heighten the risk of supine hypertension.

Drug-Food Interactions

No specific food interactions have been identified with Gutron 2.5 mg Tablet.

Drug-Disease Interactions

Gutron 2.5 mg Tablet interacts with the following diseases:

Heart Disease: Patients with severe organic heart problems should exercise caution as Gutron 2.5 mg Tablet could exacerbate their condition.
Urinary Retention: Patients experiencing difficulty in urinating due to conditions like benign prostatic hyperplasia might find their condition worsening with the use of Gutron 2.5 mg Tablet.
Thyrotoxicosis: Individuals diagnosed with thyrotoxicosis, a condition where the thyroid gland produces excessive amounts of thyroid hormone, should avoid this medication as it can potentially make their condition worse.
Pheochromocytoma: Patients with this rare tumour of the adrenal glands that causes excess production of hormones adrenaline and noradrenaline should not use Gutron 2.5 mg Tablet as it can lead to severe hypertension.

Daily Dose

The daily dose of Gutron 2.5 mg Tablet should be as directed by your doctor. This may differ depending on individual factors such as how severe your condition is and how well you respond to the medicine. It's important not to exceed the prescribed dosage without your doctor's advice.

Over Dose

If you accidentally take more Gutron 2.5 mg Tablet than you should, you may experience symptoms such as an increase in body hair, a tingling sensation, or chills. If these symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to take your Gutron 2.5 mg Tablet at the required time, take it as soon as you remember. However, if it's almost time for your next dose, leave out the missed dose and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Keep Gutron 2.5 mg Tablet in its original packaging.
Store at room temperature, ideally below 25°C.
Protect the medicine from light and moisture exposure.
Keep the medicine out of reach of children.
Make sure to use the medicine before its expiry date.

To manage orthostatic hypotension, ensure you always change positions slowly, especially when transitioning from a sitting or lying position to standing. This can help prevent dizziness and fainting.
Drinking plenty of fluids, particularly water, can help maintain an optimal blood volume which is important for maintaining blood pressure levels.

Fact Box

Drug Category	Alpha-1 Adrenergic Receptor Agonist
Therapeutic Category	Antihypotensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Orthostatic Hypotension, Autonomic Dysfunction

What is Gutron 2.5 mg Tablet used for?

It's used to manage orthostatic hypotension, a condition where your blood pressure drops upon standing, causing dizziness.

How does Gutron 2.5 mg Tablet work?

It contains midodrine which tightens blood vessels, thereby increasing blood pressure and reducing symptoms like fainting or lightheadedness.

Can I take Gutron 2.5 mg Tablet if I have heart disease?

If you have severe organic heart disease, this medicine is not recommended. Please consult your doctor.

What are the common side effects of Gutron 2.5 mg Tablet?

Common side effects include goosebumps, itching, tingling sensation, chills, urinary retention and high blood pressure when lying down.

How should I store Gutron 2.5 mg Tablet?

Store at controlled room temperature (below 25°C), away from light and moisture.

Can I take other medications while on Gutron 2.5 mg Tablet?

Some medicines may interact with Gutron. Always consult your doctor before taking new medications.

Can pregnant or nursing women take Gutron 2.5 mg Tablet?

Its use during pregnancy or breastfeeding should be considered only if the potential benefit outweighs any risks.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

References

ProAmatine®. (n.d.). ProAmatine® (midodrine hydrochloride) Tablets. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/019815s010lbl.pdf
Research, C. F. D. E. A. (2015, July 17). Midodrine information. U.S. Food And Drug Administration. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/midodrine-information
Midodrine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00211
Midodrine: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a616030.html

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