Ivabrad 75 Mg Tablet 15

Ivabrad 7.5 Tablet 15

Lupin Ltd

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Composition

Ivabradine (7.5 Mg)

Strength:

7.5 MG 5 MG

Ivabrad 7.5 Tablet is primarily used to manage symptomatic stable angina pectoris and chronic heart failure in adults. This medicine is part of a group of medicines known as hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers.

This tablet reduces the heart's oxygen demand and helps the heart pump blood more efficiently. It can decrease the risk of hospitalisation in heart failure patients by improving their heart function.

It's crucial to take this medicine orally as directed by your doctor. Make sure your doctor knows about any other illnesses you have or any other medicines you are taking before you start taking this one. If you notice any side effects while on this medicine, inform your doctor immediately. Continue taking the tablet for as long as your doctor has told you to get the most benefit from it.

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Ivabrad 7.5 Tablet is used for:

Managing symptoms of stable angina pectoris: This occurs when your heart gets less blood and oxygen than it needs.
Improving heart function in chronic heart failure: This condition means your heart is unable to pump blood as efficiently as normal.

Directions for Use of Ivabrad 7.5 Tablet 15

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Ivabrad 7.5 Tablet is taken orally.

You might experience some common side effects while using Ivabrad 7.5 Tablet:

Luminous phenomena: This refers to seeing brief flashes of light in your field of vision.
Blurred vision
Slow heart rate, also known as bradycardia
Uncontrolled blood pressure
Atrial fibrillation: This condition causes irregular and often rapid heart rate.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Ivabrad 7.5 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips to manage a couple of these side effects more comfortably:

Uncontrolled blood pressure: Seek medical attention if you notice this issue.

Ivabrad 7.5 Tablet contains ivabradine (7.5 mg), which works on your body as follows:

Inhibits If Current: Ivabradine works by selectively inhibiting the If current in your heart's natural pacemaker, known as the sinoatrial node.
Slows Down Heart Rate: By blocking the If current, ivabradine effectively slows down your heart rate by a few beats per minute.
Reduces Heart Workload: A slower heart rate means that your heart doesn't have to work as hard, which helps lower its oxygen requirements.
Improves Heart Function: The reduced workload improves your heart's ability to fill with and pump out blood efficiently.

Pregnancy

Ivabrad 7.5 Tablet is not recommended during pregnancy. If you're pregnant, it's essential to discuss this with your doctor before starting this medicine.

Breastfeeding

This medicine is not suitable for breastfeeding women. Always consult your doctor to understand potential risks and benefits.

Alcohol

It's always wise to limit your alcohol intake while managing heart conditions.

Liver

Caution is crucial if you have mild to moderate liver issues and are prescribed this medicine. It isn't recommended for severe liver diseases. Discuss any liver problems with your doctor before starting Ivabrad 7.5 Tablet.

Kidney

If you have a history of kidney problems, it's good practice to consult your doctor before taking this medicine.

Using Machines & Driving

Ivabrad 7.5 Tablet may cause visual disturbances which could affect your ability to drive or operate machinery safely. Contact your doctor if you experience these effects.

Allergy

This medicine should not be taken if you're allergic to ivabradine or any other components of the tablet. Inform your doctor about any known allergies prior to starting treatment.

Children

Caution is advised while giving Ivabrad 7.5 Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Ivabrad 7.5 Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Ivabrad 7.5 Tablet interacts with the following medicines:

CYP3A4 Inhibitors: When taken with Ivabrad 7.5 Tablet, medications like diltiazem, verapamil, azole antifungals, macrolide antibiotics, and HIV-protease inhibitors can increase ivabradine levels in the body.
CYP3A4 Inducers: Medicines such as rifampicin, barbiturates, phenytoin and St. John's wort may reduce the effectiveness of Ivabrad 7.5 Tablet by reducing ivabradine levels.
QT-Prolonging Medicines: Using Ivabrad 7.5 Tablet with medicines like quinidine, disopyramide, sotalol, and amiodarone can increase the risk of ventricular arrhythmias.

Drug-Food Interactions

Ivabrad 7.5 Tablet interacts with grapefruit juice, which can increase ivabradine levels in the body.

Drug-Disease Interactions

Ivabrad 7.5 Tablet interacts with the following diseases:

Atrial Fibrillation: Because Ivabrad 7.5 Tablet can increase the risk of this condition, patients should be monitored regularly.
Bradycardia: Ivabradine in Ivabrad 7.5 Tablet can cause severe bradycardia; this medicine should not be started if the resting heart rate is below 70 bpm.
Hypertension: Blood pressure should be monitored during the first month of treatment with Ivabrad 7.5 Tablet as ivabradine can cause elevated blood pressure.
Chronic Heart Failure: Ivabrad 7.5 Tablet should be used only in stable chronic heart failure patients, not for acute heart failure treatment.

Daily Dose

The daily dose of Ivabrad 7.5 Tablet should be taken as guided by your doctor. The dosage may vary depending on things like how severe your condition is and how well you respond to the medicine. It's vital to stick to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed amount of Ivabrad 7.5 Tablet, you could experience symptoms like a slow heart rate or feeling dizzy. In case of overdosage, do not delay and seek medical help right away.

Missed Dose

If you realise you've missed a dose of Ivabrad 7.5 Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the one you missed and continue with your regular schedule. Never adjust your dosage without talking to your doctor first.

Store your Ivabrad 7.5 Tablet at a room temperature below 30°C.
Avoid exposure to light and moisture.
Keep the medicine out of reach and sight of children.
Always check the expiry date on the package before taking the tablet.

For managing stable angina, incorporate regular, moderate exercise into your lifestyle. This improves blood flow to the heart.
As part of managing chronic heart failure, consider reducing sodium intake in your diet. Excess salt can lead to fluid retention worsening heart failure symptoms.

Fact Box

Drug Category	HCN Channel Blocker
Therapeutic Category	Cardiovascular Medicine
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Stable Angina Pectoris, Chronic Heart Failure

What is Ivabrad 7.5 Tablet used for?

Ivabrad 7.5 Tablet is a medicine used to manage symptoms of stable angina, a type of chest pain, and chronic heart failure in adults.

How does Ivabrad 7.5 Tablet work?

This medicine contains ivabradine which slows down the heart rate, reducing the heart's workload and oxygen requirements, thereby improving heart function.

Can I take Ivabrad 7.5 Tablet during pregnancy or while breastfeeding?

No, Ivabrad 7.5 Tablet is not recommended during pregnancy or while breastfeeding. Always consult your doctor for advice.

How long before I see improvements with Ivabrad 7.5 Tablet?

Symptom improvement is usually noted within 2-4 weeks, however, it may take 3-4 months for the full benefit to be experienced.

What should I do if I miss a dose of Ivabrad 7.5 Tablet?

Take the missed dose as soon as you remember unless it's almost time for the next dose. Don't double the dose; stick to your regular schedule.

Can I stop taking Ivabrad 7.5 Tablet if I feel better?

No, do not stop taking this medicine without consulting your doctor, even if you feel better, as it could worsen your symptoms.

Are there any particular foods or drinks I should avoid while taking Ivabrad 7.5 Tablet?

Yes, avoid consuming grapefruit juice while taking this medicine as it can increase ivabradine levels in your blood.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

References

https://go.drugbank.com/drugs/DB09083
Amgen. (2015). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/209964lbl.pdf
VA Pharmacy Benefits Management Services, Medical Advisory Panel, and VISN Pharmacist Executives. (2015). Ivabradine Drug Monograph. https://www.pbm.va.gov/PBM/clinicalguidance/drugmonographs/Ivabradine_CORLANOR_Monograph.pdf
Ivabradine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09083
Fala, L. (2016, March 1). Corlanor (Ivabradine), First HCN Channel Blocker, FDA Approved for the Treatment of Patients with Heart Failure. PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013853/
Tse, S., & Mazzola, N. (2015, December 1). Ivabradine (Corlanor) for heart failure: the first selective and specific if inhibitor. PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671466/

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