Longifene 25 Mg Tablet 10

Longifene Tablet 10

Mankind Pharmaceuticals Ltd.

Strip of 10 Units

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MRP ~~₹38.7~~

₹31.73

₹3.87/Units

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Composition

Buclizine (25 Mg)

Longifene Tablet is primarily used to manage various allergic conditions and to prevent and mitigate symptoms associated with motion sickness. It belongs to the class of piperazine antihistamines.

In addition to managing allergies, this medicine is particularly useful when you are travelling. Motion sickness during travel can cause discomfort in the form of nausea, dizziness, vomiting, and other unpleasant symptoms. This tablet helps in reducing these symptoms effectively, making your journey more comfortable.

Before starting this medication, it's important to consult your doctor who will guide you on the correct dosage and frequency based on your specific condition. Always inform your doctor about any pre-existing conditions or ongoing medications that you are taking. If you experience any side effects while using this medicine, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

Management of allergic conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria (also known as hives).
Prevention and management of motion sickness, reducing symptoms like nausea, vomiting, and dizziness experienced during travel.

Directions for Use of Longifene Tablet 10

Swallow the tablet whole with a glass of water.
Do not chew or crush the tablet.
The medicine can be taken with or without food.
Always follow your doctor's instructions on when and how to take this medicine.
Do not exceed the recommended dose without consulting your doctor.
If you're unsure about any aspect of using Longifene Tablet, consult your doctor for guidance.

Longifene Tablet is taken orally.

Drowsiness
Dry mouth
Blurred vision
Constipation
Difficulty urinating
Headache
Dizziness
Fatigue

Managing the Side Effects:

Drowsiness: Consider taking Longifene Tablet at night to lessen the impact of drowsiness during your daily activities.
Dry mouth: Try taking your dose with a full glass of water to help manage dry mouth.

Longifene Tablet consists of buclizine (25 mg), which works as follows:

Antihistamine Action: Buclizine competitively binds with H1 histamine receptors in the body. These receptors are responsible for allergy symptoms like itching, sneezing, runny nose, and watery eyes. When Buclizine attaches to these receptors instead of histamine, it helps reduce these allergy symptoms.
Anticholinergic Action: Besides being an antihistamine, Buclizine also exhibits mild anticholinergic properties. It blocks muscarinic receptors located in certain parts of your brain that control vomiting and balance (vestibular apparatus). This action helps prevent nausea, dizziness and other symptoms related to motion sickness.

Pregnancy

Exercising caution is recommended while using Longifene Tablet when you're pregnant. It's best to consult your doctor before taking this medicine.

Breastfeeding

It's advised to talk to your doctor before using Longifene Tablet if you are breastfeeding.

Alcohol

Alcohol interaction with Longifene Tablet can enhance the drowsiness effect. It's advisable to limit alcohol consumption while using this medicine.

Liver

If you have liver health concerns, it's important to consult your doctor before using Longifene Tablet.

Kidney

If you have any kidney health issues, it's recommended to consult your doctor before taking this medicine.

Using Machines & Driving

Since Longifene Tablet may cause drowsiness, caution is advised while driving or operating machinery until you know how this medicine affects you.

Allergy

If you have known allergies to buclizine or any other ingredients in Longifene Tablet, avoid taking this medicine. Consult your doctor for alternatives.

Children

Longifene Tablet should be given to children only upon the advice of a doctor.

Older Patients

Elderly patients may be more sensitive to the effects of Longifene Tablet, especially drowsiness and anticholinergic side effects. Thus, older patients should use this medicine under medical supervision.

Drug-Drug Interactions

CNS Depressants: Medicines like sedatives (e.g., diazepam) and tranquillizers (e.g., lorazepam) can increase drowsiness when taken with Longifene Tablet. Alcohol, also a CNS depressant, has similar effects.
Anticholinergic Medicines: When taken with Longifene Tablet, medicines like atropine and tricyclic antidepressants (e.g., amitriptyline) may enhance side effects such as dry mouth, constipation, and difficulty urinating.
Monoamine Oxidase Inhibitors (MAOIs): Combining Longifene Tablet with MAOIs (e.g., phenelzine) may intensify anticholinergic effects, leading to increased side effects.

Drug-Food Interactions

No specific food items have been identified that interact with Longifene Tablet. However, it's always best to take this medicine after meals to avoid any potential stomach upset.

Drug-Disease Interactions

Glaucoma: This medicine may worsen symptoms in patients suffering from glaucoma, as it contains anticholinergic properties.
Urinary retention: Longifene Tablet could exacerbate urinary retention due to its anticholinergic activity.
Gastrointestinal obstruction: This medication should be used cautiously by individuals with gastrointestinal obstructions as it may affect bowel movement.

Daily Dose

Your doctor will prescribe the daily dose of Longifene Tablet. This will depend on factors such as your specific condition and how you respond to the medicine. Always adhere to the dosage prescribed by your doctor, without exceeding it.

Over Dose

In case you accidentally take more Longifene Tablets than prescribed, you might feel drowsy or confused. There's no need to panic; however, it's important to inform your doctor about this to ensure any necessary adjustments can be made to your dosage.

Missed Dose

If you've missed a dose of Longifene Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Keep Longifene Tablet in a dry place, ideally at a temperature not exceeding 30°C.
Shield the medicine from light to maintain its effectiveness.
Always keep this medicine out of reach and sight of children.
Make sure to use Longifene Tablet before the expiry date mentioned on the packaging.

If you are taking Longifene Tablet for managing allergic conditions, try to identify your allergens and limit their intake. This could include certain foods, pollen, dust, or pet dander.
For those using this medicine to manage motion sickness, try to avoid heavy meals before travelling. Opt for light foods that are easy to digest.

Fact Box

Drug Category	Antihistamine, Anticholinergic
Therapeutic Category	Anti-allergic, Antiemetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Allergic conditions, Motion sickness

What is the main use of Longifene Tablet?

Longifene Tablet is primarily used to manage allergic conditions like allergic rhinitis and hives, as well as to prevent motion sickness symptoms such as nausea and dizziness.

How does Longifene Tablet work?

Longifene Tablet, containing Buclizine, works by blocking histamine receptors in the body to reduce allergy symptoms and by inhibiting certain brain receptors to prevent motion sickness.

Can I drive after taking Longifene Tablet?

Longifene Tablet might cause drowsiness. It's advisable not to drive or operate machinery until you know how this medicine affects you.

Can I take Longifene Tablet if I'm pregnant?

If you're pregnant, it's advisable to consult your doctor before taking this medicine.

What should I do if I accidentally take an extra dose?

In case of an accidental overdose, seek immediate medical attention. Overdosing can lead to severe drowsiness, confusion, hallucinations or respiratory depression.

What are the common side effects of Longifene Tablet?

Common side effects include drowsiness, dry mouth, blurred vision, constipation and fatigue. If any side effect persists or becomes bothersome, inform your doctor.

Can I consume alcohol while on Longifene Tablet?

It's recommended to avoid alcohol as it can increase the risk of drowsiness and impair alertness when combined with Buclizine, the active ingredient in Longifene Tablet.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

208, Okhla Industrial Estate, Phase-III, New Delhi South Delhi DL 110020 IN

Country of origin: INDIA

References

Cayman Chemical Co. (2022). Safety Data Sheet [Report]. https://cdn.caymanchem.com/cdn/msds/25641m.pdf
Buclizine: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00354
UNII - 58FQD093NU. (n.d.). https://precision.fda.gov/uniisearch/srs/unii/58fqd093nu
PubChem. (n.d.). Buclizine. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Buclizine

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