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CompositionLupihope Tablet is used to manage various female reproductive disorders such as a progestin (synthetic progesterone), it helps regulate the menstrual cycle, reduce menstrual pain and bleeding, manage premenstrual syndrome (PMS), endometriosis, and support pregnancy in women with infertility or recurrent miscarriage due to hormonal imbalance. Take this medicine orally as prescribed and inform your doctor of any pre-existing conditions or ongoing medications.
Lupihope Tablet is used to treat progesterone deficiency in women. It helps manage menstrual disorders, premenstrual syndrome (PMS), endometriosis, infertility, and supports early pregnancy to prevent miscarriages. The medicine contains dydrogesterone and is commonly used in hormone replacement and fertility care.
Swallow the tablet whole with a glass of water.
Avoid chewing or crushing the tablet.
Do not exceed the recommended dose without consulting your doctor.
Remember, it's important not to stop taking this medicine without speaking to your doctor first.
Lupihope Tablet is taken orally.
Lupihope Tablet may cause headaches, nausea, bloating, breast tenderness, irregular menstrual bleeding, weight gain, and mood changes. If you notice your symptoms getting worse or if you experience any unusual reactions, please consult with your doctor right away for advice.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Lupihope Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Nausea: Try taking Lupihope Tablet with food to lessen this effect.
Bloating: If you notice bloating, consider taking this medicine after meals.
Lupihope Tablet contains dydrogesterone (10 mg) which works on your body as follows:
Preparing the Uterine Lining: Dydrogesterone helps prepare the lining of your womb (the endometrium) for the implantation of a fertilised egg. This is a crucial step in the process of pregnancy.
Maintenance of Pregnancy: After a fertilised egg has been implanted, dydrogesterone aids in maintaining the endometrium throughout pregnancy, reducing the risk of premature labour.
Regulation of Menstrual Cycle: Dydrogesterone also regulates the growth and shedding of the endometrium during the menstrual cycle. This can help manage conditions like heavy or irregular periods.
Reduction of Uterine Contractions: Dydrogesterone reduces uterine contractions, which is particularly important during pregnancy to prevent preterm labour.
Modulation of Estrogen Activity: Dydrogesterone helps modulate the activity of estrogen in breast and endometrial tissue, ensuring a balance between these two crucial hormones.
Lupihope Tablet is contraindicated during pregnancy. If you're pregnant or planning to be, it's crucial to discuss this with your doctor before starting this medicine.
As with pregnancy, Lupihope Tablet is also contraindicated for breastfeeding women. It's advisable to talk to your doctor about the potential risks and benefits before initiating this medication.
Caution is advised, and it's best to consult your doctor for guidance.
Caution is advised while taking Lupihope Tablet if you have mild to moderate liver impairment. It's not recommended if you have severe liver diseases. Discuss your liver health with your doctor before starting this medicine, as it could affect liver function.
There isn't enough data about Lupihope Tablet's effect on kidney health. If you have any history of kidney problems, it's a good idea to consult your doctor before taking this medicine.
Lupihope Tablet may cause side effects like headaches, which could affect your ability to drive or operate machinery. It's advisable to understand how this medicine affects you before engaging in such activities.
If you're allergic to dydrogesterone or any other ingredients of Lupihope Tablet, avoid taking this medicine. Inform your doctor if you have any known allergies.
Lupihope Tablet isn't generally prescribed for children under 18 years of age. Always consult your doctor before giving any medicine to a child.
Older patients should take Lupihope Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age due to potential liver and kidney issues. Your doctor will guide you based on your health status.
Lupihope Tablet interacts with the following medicines:
Anticonvulsants: Medicines such as phenytoin and carbamazepine can decrease the levels of dydrogesterone in your body. This may reduce the effectiveness of Lupihope Tablet.
Hormone Replacement Therapy (HRT): If you're on HRT with oestrogens, you might experience increased side effects when you take Lupihope Tablet.
Antidiabetic Agents: Medications like insulin and metformin may need dose adjustments. That's because dydrogesterone in Lupihope Tablet can affect your body's glucose tolerance.
There are no known specific food interactions with Lupihope Tablet.
Lupihope Tablet interacts with the following diseases:
Liver Disease: If you have a liver condition, using Lupihope Tablet might not be safe since dydrogesterone undergoes extensive metabolism in the liver.
Diabetes Mellitus: Dydrogesterone can affect glucose tolerance, so if you have diabetes, taking this medication may require close monitoring of your blood sugar levels.
Hypertension: Be cautious if you have high blood pressure. Dydrogesterone might cause fluid retention, which can worsen hypertension.
Migraine: If you suffer from migraines, this medication could potentially trigger more frequent or severe migraine attacks.
The daily dose of Lupihope Tablet should be taken as directed by your doctor. The dosage could vary based on factors such as how severe your condition is and how well you respond to the medicine. Please adhere strictly to the prescribed dosage and avoid exceeding it without consulting your doctor.
Overdosing on Lupihope Tablet may lead to common side effects like feeling sick or headaches. If you accidentally take more than your prescribed dose, don't worry, but do let your doctor know.
If you forget to take your Lupihope Tablet, take it as soon as you remember. But, if it's nearly time for your next dose, skip the one you missed and continue with your regular schedule. You should never increase your dosage without speaking to your doctor first.
Store Lupihope Tablet at room temperature, ideally below 30°C.
Keep it in a dry place, shielded from direct light and moisture.
It's crucial to keep this medicine out of the reach of children.
Always ensure you use your Lupihope Tablet before its expiry date.
If you're dealing with premenstrual syndrome (PMS) or painful menstruation, reducing your intake of caffeine may help alleviate symptoms, as it can sometimes intensify discomfort.
For those managing endometriosis with Lupihope Tablet, incorporating gentle exercise into your routine could be beneficial. Physical activity can help manage pain and improve overall wellbeing. However, always consult your doctor before starting any new fitness regime.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Female Infertility, Dysmenorrhea, Endometriosis |
| Drug Category | Progestin |
| Therapeutic Category | Female Hormone |
Lupihope Tablet contains dydrogesterone, which helps manage female reproductive disorders by mimicking the natural hormone progesterone.
Yes, dydrogesterone in Lupihope Tablet can support pregnancy in women having difficulty conceiving due to hormonal imbalances.
No, Lupihope Tablet is not recommended during pregnancy. If you become pregnant while taking this medicine, consult your doctor immediately.
It helps manage endometriosis by regulating the growth of the uterine lining, which can reduce pain and abnormal bleeding.
Long-term use is generally not suggested due to potential side effects. Consult your doctor for the optimal duration of use.
Common side effects include headache, nausea, bloating, breast tenderness, irregular menstrual bleeding, weight gain, and mood changes.
Yes, certain medicines like hepatic enzyme inducers and hormone replacement therapy may interact with Lupihope Tablet. Always inform your doctor about all the medicines you're taking.
Check out Editorial Policy
Dydrogesterone. (2021). DUPHASTON [Pharmacological]. https://registrasiobat.pom.go.id/files/assesment-reports/obat_baru/Duphaston.pdf
PubChem. (n.d.). Dydrogesterone. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Dydrogesterone
Dydrogesterone: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00378
Taniguchi, F., Ota, I., Iba, Y., Toda, T., Tagashira, Y., Ohata, Y., Kurioka, H., Endo, Y., Sunada, H., Noma, H., Azuma, Y., & Harada, T. (2018). The efficacy and safety of dydrogesterone for treatment of dysmenorrhea: An open‐label multicenter clinical study. Journal of Obstetrics and Gynaecology Research, 45(1), 168–175. https://doi.org/10.1111/jog.13807
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