Methygene Tablet 10

Intas Pharmaceuticals Ltd

Strip of 10 Units

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MRP ~~₹95.47~~

₹76.38

₹9.55/Units

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Prescription required for this medicine

Store Below 30° C

Composition

Methylergometrine (0.125 Mg)

Methygene Tablet 10 is used to treat heavy uterine bleeding, especially after childbirth or abortion. It is a single-ingredient medicine containing methylergometrine, which helps control excessive blood loss and supports faster recovery.

This medicine is widely used in women's health to manage abnormal bleeding and reduce risks from heavy menstrual flow, and is also used in the third stage of labour, assisting in the expulsion of the placenta and helping to prevent postpartum haemorrhage.

Report side effects such as nausea, headache or abdominal discomfort promptly.

Methygene Tablet 10 is used to manage excessive bleeding after childbirth.

Uses of Methygene Tablet 10 are:

Postpartum Haemorrhage: Helps prevent and manage excessive bleeding after childbirth.
Uterine Subinvolution: Aids in the uterus returning to its normal size after delivery.
Third Stage of Labour: Helps in the removal of the placenta during delivery.

Consume this medicine orally as instructed by your doctor.
Swallow the tablet whole with a glass of water.
Abstain from crushing, chewing or breaking the tablet.
The precise dose and duration will be determined by your doctor depending on your condition and response.
Remember not to stop taking this medicine without prior consultation with your doctor.

Methygene Tablet 10 is taken orally.

Methygene Tablet 10 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Methygene Tablet 10:

Digestive: Nausea, vomiting, abdominal pain and cramps.
Nervous system: Headache and dizziness.
Cardiovascular: Elevated blood pressure.

If any side effect does not improve or becomes serious, speak to your doctor.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Methygene Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some suggestions to manage common side effects:

Nausea and vomiting: Try taking Methygene Tablet 10 with food to mitigate these symptoms.
Elevated blood pressure: Monitor your blood pressure regularly while on this medication. If it rises significantly, consult your doctor immediately.

Methygene Tablet 10 contains methylergometrine (0.125 mg), and its activity in the body can be explained as follows:

Direct Uterine Action: Methylergometrine acts directly on the smooth muscles of the uterus. It increases the tone, rate and strength of rhythmic uterine contractions.
Reduced Blood Loss: By stimulating strong uterine contractions, methylergometrine compresses blood vessels which leads to reduced blood loss.
Uterotonic Effect: This effect helps in preventing and controlling postpartum haemorrhage by inducing strong contractions in the uterus.

Pregnancy

Methygene Tablet 10 is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Methygene Tablet 10 is contraindicated for breastfeeding/lactating women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised while taking Methygene Tablet 10 if you consume alcohol regularly. It is best to consult your doctor before taking this medicine.

Liver

Caution is advised while taking Methygene Tablet 10 in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Methygene Tablet 10. This medicine may affect liver function.

Kidney

Caution is advised before using Methygene Tablet 10 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Use In Driving And Operating Machinery

Methygene Tablet 10 might cause dizziness. Therefore, caution is advised while driving or operating heavy machinery. Consult your doctor for more information.

Allergy

If you are allergic to methylergometrine or any other ingredients in Methygene Tablet 10, avoid taking it and consult your doctor.

Children

Methygene Tablet 10 is meant for adults and should not be given to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Methygene Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Methygene Tablet 10 interacts with the following medicines:

Ergot Alkaloids: Medicines like ergotamine may interact with Methygene Tablet 10, potentially leading to an amplified effect due to similar mechanisms of action.
Antivirals: Medicines like ritonavir may increase the blood concentration of Methygene Tablet 10, potentially heightening its effects and side effects.
Azole Antifungals: Antifungal medications like fluconazole and itraconazole may enhance the effects of Methygene Tablet 10 by reducing its breakdown in the body.
Antidepressants (MAO Inhibitors): These medications, such as phenelzine, interact with Methygene Tablet 10 and can increase the risk of hypertension.

Drug-Food Interactions

Methygene Tablet 10 does not have any known specific interactions with food items.

Drug-Disease Interactions

Methygene Tablet 10 interacts with the following diseases:

Hypertension and Preeclampsia: Methygene Tablet 10 can elevate blood pressure, thereby worsening these conditions.
Coronary Artery Disease: This medicine could potentially exacerbate heart-related symptoms in patients with this condition.
Peripheral Vascular Disease: The use of Methygene Tablet 10 may worsen symptoms in individuals suffering from this condition.
History of Stroke or Seizures: This medicine could potentially increase the risk of seizures or stroke in patients with a past history of these conditions.

Daily Dose

Take the daily recommended dose of Methygene Tablet 10 as advised by your doctor, taking into account the severity of your condition and how you respond to the medication. Make sure you stick to the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

In case of an accidental overdose of Methygene Tablet 10, you might experience symptoms such as nausea, vomiting, abdominal pain, or breathing difficulties. If these symptoms persist or worsen, make sure to inform your doctor.

Missed Dose

If you happen to miss a dose of Methygene Tablet 10, take it as soon as you remember. However, if it's nearly time for your next dose, simply skip the missed one and continue with your regular dosage schedule. Never adjust your dosage without consulting your doctor.

Store Methygene Tablet 10 at room temperature, ideally below 30°C.
Keep away from direct light and moisture to maintain its effectiveness.
Ensure it's out of reach of children and pets to prevent accidental ingestion.
Always check the expiry date before use and avoid taking expired medicine.

Try to maintain a balanced diet rich in iron to counteract potential blood loss, which this medicine helps manage. Iron-rich foods include leafy greens, lentils, and meat.
Since Methygene Tablet 10 is used after childbirth or abortion, rest is crucial for recovery. Aim for uninterrupted sleep and take short breaks throughout the day to help your body heal.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Postpartum Haemorrhage, Uterine Subinvolution
Drug Category	Uterotonic
Therapeutic Category	Ergot Alkaloid

What is the main use of Methygene Tablet 10?

Methygene Tablet 10 is primarily used to prevent and control excess bleeding from the uterus after childbirth or abortion.

How does Methygene Tablet 10 work?

Methygene Tablet 10 increases the tone, rate, and strength of uterine contractions, reducing blood loss by compressing blood vessels in the uterus.

Can I take Methygene Tablet 10 while breastfeeding?

Methygene Tablet 10 should be avoided during breastfeeding as methylergometrine can pass into breast milk and may affect the baby.

Can I take other medicines while using Methygene Tablet 10?

Some medicines can interact with Methygene Tablet 10, affecting its effectiveness. Always consult your doctor before starting any new medication.

What should I do if I miss a dose of Methygene Tablet 10?

If you miss a dose, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one.

What are the common side effects of Methygene Tablet 10?

Common side effects include nausea, vomiting, abdominal pain, cramps, headache, dizziness and elevated blood pressure.

How should I store my Methygene Tablet 10?

Methygene Tablet 10s should be stored at room temperature (25°C), away from light and moisture and out of reach of children and pets.

Last Updated On 16 Sep. 2026 | 7:31AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 10 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 10 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India

Country of origin: INDIA

Expiry on or after: January 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Methergine®(methylergonovine maleate) . (N.d.). Fda.Gov. Retrieved August 28, 2024, from
https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/006035s078lbl.pdf
Unknown Unknown, U., Unknown. (n.d.). METHYLERGONOVINE b (Systemic) [Report]. https://simsrc.edu.in/pdf_df/M-drugs/methylergonovine.pdf
Methergine. (n.d.). https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=b1552d48-86f5-4184-810a-001e57e96c02&type=display
PubChem. (n.d.). Methylergonovine. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Methylergonovine
Methylergometrine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00353

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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