Mirabet 25 Mg Tablet Er 10

Mirabet 25 Tablet 10

Macleods Pharmaceuticals Pvt.ltd

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Composition

Mirabegron (25 Mg)

Strength:

50 MG 25 MG

Mirabet 25 Tablet is primarily used to manage the symptoms of overactive bladder, a condition that causes a sudden urge to urinate. This medicine falls under the category of beta-3 adrenergic agonists.

It also helps in reducing urinary frequency and urge incontinence, which are common issues associated with an overactive bladder. These additional benefits make this medicine a comprehensive solution for overactive bladder symptoms.

This medicine should be taken orally as directed by your doctor. You must inform your doctor about any pre-existing conditions or ongoing medicines before starting this medicine. If you notice any side effects while on this medicine, consult your doctor immediately. For optimal results, you must continue taking the medicine for the duration prescribed by your doctor.

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Mirabet 25 Tablet is used for the following:

Managing overactive bladder: This condition involves sudden and uncontrolled urges to urinate.
Controlling urinary frequency: The medicine helps if you are urinating more than normal, typically 8 or more times a day.
Handling urge incontinence: This is when there are leakage or wetting accidents due to a strong need to urinate.

Directions for Use of Mirabet 25 Tablet 10

Swallow the tablet whole with a glass of water.
Do not chew, divide, or crush the tablet.
Always follow your doctor's advice on how often to take this medicine.
Remember, if you have any questions about how to take this medication, it's best to consult your doctor.

Mirabet 25 Tablet is taken orally.

Common side effects of Mirabet 25 Tablet include:

Hypertension: This refers to an increase in blood pressure.
Nasopharyngitis: An inflammation in the throat and nasal passages.
Urinary Tract Infection (UTI): This is an infection that affects any part of your urinary system, which includes your kidneys, bladder, ureters and urethra.
Headache
Constipation
Dizziness
Back pain

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve by discontinuing the use of Mirabet 25 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips to manage common side effects:

Constipation: Try taking Mirabet 25 Tablet with plenty of fluids and a fibre-rich diet.
Dizziness: Consider taking this medicine before bed to lessen this effect.

Mirabet 25 Tablet contains mirabegron (25 mg), which works on the body as follows:

Activation of Beta-3 Adrenergic Receptors: Mirabegron stimulates these receptors, which are present in the muscle of the bladder. This action helps relax the bladder muscle.
Reducing Involuntary Bladder Contractions: By relaxing the bladder muscle, mirabegron effectively reduces involuntary contractions of the bladder.
Increasing Bladder Storage Capacity: The relaxation brought about by mirabegron increases the storage capacity of the bladder, thereby reducing urinary frequency.

Pregnancy

If you're pregnant, Mirabet 25 Tablet should be used only when the potential benefits outweigh the possible risks. Best to consult your doctor before using this medicine.

Breastfeeding

Mirabegron, the active ingredient in Mirabet 25 Tablet, is predicted to be excreted in human milk. Therefore, it's advised not to use this medicine while breastfeeding.

Alcohol

There are no known interactions of Mirabet 25 Tablet with alcohol. However, if you regularly drink alcohol, it is advisable to discuss it with your doctor before starting this medication.

Liver

People with moderate liver health issues should take a maximum dose of 25 mg once daily. For those with severe liver impairments, taking Mirabet 25 Tablet is not recommended.

Kidney

For those having severe kidney problems, the maximum dose for Mirabet 25 Tablet is 25 mg once daily. It's not recommended if you have end-stage kidney disease.

Using Machines & Driving

There are no specific warnings about operating machinery or driving while taking Mirabet 25 Tablet. However, as dizziness is a potential side effect, caution is advised until you know how this medicine affects you.

Allergy

If you are allergic to mirabegron or any other ingredients of the Mirabet 25 Tablet, avoid using it. If unsure about any allergies, consult your doctor first.

Children

The safety and effectiveness of Mirabet 25 Tablet have not been established for children. Caution is advised when considering this medication for individuals under the age of 18 years.

Older Patients

Mirabet 25 Tablet does not require dose adjustment for elderly patients. However, since older people might have liver or kidney issues and could be on other medications, it's advisable to discuss any concerns with your doctor before starting this medicine.

Drug-Drug Interactions

Mirabet 25 Tablet interacts with the following medicines:

Beta-blockers (e.g., metoprolol, propranolol): Mirabegron may increase the blood levels of these medicines, leading to enhanced blood pressure-lowering effects or slower heart rates.
Anticholinergic medications (e.g., tolterodine, solifenacin): When used together, they may increase the risk of side effects such as dry mouth, constipation, and blurred vision.
QT-prolonging agents (e.g., amiodarone, sotalol): Combining with mirabegron may increase the risk of abnormal heart rhythms.

Drug-Food Interactions

There are no specific food interactions known for Mirabet 25 Tablet.

Drug-Disease Interactions

Mirabet 25 Tablet interacts with the following diseases:

Hypertension: Mirabet 25 Tablet can raise blood pressure, so if you have hypertension, regular blood pressure monitoring is recommended.
Severe Renal Impairment: Patients with severe renal impairment should take a maximum dose of 25 mg once daily. It's not recommended for those with end-stage renal disease.
Moderate Hepatic Impairment: For patients with moderate hepatic impairment, the maximum recommended dose is also 25 mg once daily. It's not suggested for use in patients with severe hepatic impairment.
Bladder Outlet Obstruction (BOO): Use this medicine cautiously if you have BOO because there's a risk of urinary retention.

Daily Dose

The daily dose of Mirabet 25 Tablet should be as prescribed by your doctor. This may vary based on individual factors like the severity of your condition and how you respond to the medicine. Always follow your doctor's prescribed dosage and never exceed it without their advice.

Over Dose

If you accidentally take more than the recommended dose of Mirabet 25 Tablet, you could experience symptoms such as hypertension, constipation, or headaches. If this happens, consult your doctor for advice.

Missed Dose

If you forget to take a dose of Mirabet 25 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the one you missed and continue with your regular schedule. Never double up on doses without consulting your doctor.

Always keep the Mirabet 25 Tablet in its original packaging.
Store at room temperature, ideally below 30°C.
Ensure the bottle is tightly closed to protect it from moisture.
Keep out of reach of children.
Always use before the expiry date mentioned on the package.

To help manage symptoms of overactive bladder, limit your caffeine intake. Caffeine can irritate your bladder and increase urgency.
Incorporate pelvic floor exercises into your daily routine. These exercises can strengthen your bladder muscles and improve urinary control.

Fact Box

Drug Category	Beta-3 Adrenergic Agonist
Therapeutic Category	Urinary Antispasmodic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Overactive Bladder, Urinary Incontinence, Urinary Frequency

What is Mirabet 25 Tablet used for?

It's a medicine meant to manage symptoms of overactive bladder, such as sudden urges to urinate, frequent urination, and wetting accidents.

How does Mirabet 25 Tablet work?

The active ingredient in Mirabet 25 Tablet, mirabegron, stimulates receptors in your bladder muscle, helping it relax. This increases storage capacity and reduces involuntary contractions.

Can I take Mirabet 25 Tablet if I'm pregnant?

You should consult your doctor before taking this medicine during pregnancy. It should only be used if the potential benefit outweighs the possible risk to the baby.

Is it safe to use Mirabet 25 Tablet while breastfeeding?

Since mirabegron may be present in breast milk, it's not recommended for nursing mothers. Always consult your doctor before using this medicine.

How long does it usually take for Mirabet 25 Tablet to start working?

Generally, you might notice improvement in your symptoms within eight weeks of starting the medication. However, individual responses can vary.

What should I do if I forget to take a dose of Mirabet 25 Tablet?

If you miss a dose, take it as soon as you remember. If it's near time for your next dose, skip the missed one and continue with your normal schedule.

Can my child take Mirabet 25 Tablet?

The safety and effectiveness of Mirabet 25 Tablet have not been established for children. Please consult your doctor for appropriate medication options for your child.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Atlanta Arcade, Marol Church Rd, Bori Colony, Vijay Nagar Colony West, Marol, Andheri East, Mumbai, Maharashtra 400059

Country of origin: INDIA

References

Astellas Pharma US, Inc. (2012). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202611s000lbl.pdf
Betmiga. (n.d.). Betmiga Summary of product characteristics. https://www.ema.europa.eu/en/documents/product-information/betmiga-epar-product-information_en.pdf
Dawood, O., & El-Zawahry, A. (2023, August 28). Mirabegron. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK538513/
PubChem. (n.d.). Mirabegron. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Mirabegron
Mirabegron: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB08893

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