Mofetyl 500 Mg Tablet 10

Mofetyl 500 Tablet 10

Rpg Life Sciences Ltd.

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MRP ~~₹783.05~~

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Composition

Mycophenolate Mofetil (500 Mg)

Strength:

500 MG 250 MG

Mofetyl 500 Tablet is mainly used to prevent organ rejection in individuals who have undergone kidney, heart, or liver transplants. This medicine is part of a group known as immunosuppressants, which help to suppress the immune system.

In addition to preventing organ rejection, this medicine is also used with other immunosuppressant medicines like cyclosporine and corticosteroids. By working together, these medicines stop the body's immune system from attacking and rejecting the newly transplanted organ, which it might recognise as foreign.

Before starting on this medicine, you should consult your doctor about the suitable dosage and frequency. It's crucial to disclose any pre-existing conditions or existing medications to your doctor. If you experience any side effects while using this medicine, inform your doctor immediately. It's important to continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Mofetyl 500 Tablet is typically utilised for the following purposes:

Prevention of organ rejection following a kidney transplant
Stopping the body from rejecting a new heart after a heart transplant
Avoiding organ rejection after a liver transplant

Directions for Use of Mofetyl 500 Tablet 10

Here's how to take Mofetyl 500 Tablet:

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Mofetyl 500 Tablet is taken orally.

Mofetyl 500 Tablet may have the following common side effects:

Diarrhoea
Nausea
Abdominal pain
Fever
Leukopaenia: This is a condition where the number of white blood cells in your body decreases, which might make you prone to infections.
Thrombocytopaenia: This refers to a decrease in the number of platelets, which are cells that help your blood clot.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Mofetyl 500 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some suggestions for managing common side effects:

Diarrhoea: Drink plenty of healthy fluids to stay hydrated and follow the diet recommended by your doctor.
Nausea: Follow the dietary recommendations provided by your doctor.

Mofetyl 500 Tablet contains mycophenolate mofetil (500 mg). Let’s take a look at how it works on your body:

IMPDH Inhibition: Mycophenolate mofetil blocks an enzyme named inosine monophosphate dehydrogenase (IMPDH). This enzyme is vital in forming guanosine nucleotides, which are necessary for cell growth.
Impact on Lymphocytes: The component specifically targets T and B-lymphocytes, cells that play a key role in attacking new organs post-transplant. By reducing guanosine nucleotides, it inhibits the growth of these lymphocytes.

Pregnancy

Mofetyl 500 Tablet is contraindicated during pregnancy. If you are expecting or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Mofetyl 500 Tablet is not recommended for breastfeeding women. It is crucial to consult your doctor to understand the potential risks and benefits.

Alcohol

The interaction of Mofetyl 500 Tablet with alcohol is negligible. However, reducing alcohol consumption can improve your overall health.

Liver

Caution is advised while taking Mofetyl 500 Tablet if you have liver health issues. It would be wise to discuss any liver-related concerns with your doctor before starting this medication.

Kidney

If you have a history of kidney problems, it's a good idea to consult your doctor before taking Mofetyl 500 Tablet.

Using Machines & Driving

Mofetyl 500 Tablet does not affect your ability to operate machinery or drive. Consult your doctor for advice in this regard.

Allergy

Mofetyl 500 Tablet should not be taken if you're allergic to mycophenolate mofetil or any other ingredients in the tablet.

Children

Caution is advised when giving Mofetyl 500 Tablet to children under 18 years of age. Always consult your doctor before administering any medicine to a child.

Older Patients

Older patients should use Mofetyl 500 Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Mofetyl 500 Tablet interacts with the following medicines:

Antacids: Medicines containing magnesium and aluminium hydroxide, such as Gaviscon and Mylanta, can decrease the absorption of Mofetyl 500 Tablet.
Immunosuppressants: Medicines like azathioprine should not be used with this medication due to similarities in their action.
Antibiotics: Rifampicin can decrease levels of the active ingredient in Mofetyl 500 Tablet.
Antivirals: Acyclovir and ganciclovir can interact with this medicine, affecting its levels.

Drug-Food Interactions

Mofetyl 500 Tablet has no known specific food interactions.

Drug-Disease Interactions

Mofetyl 500 Tablet interacts with the following diseases:

Renal Impairment: Patients with severe kidney problems should approach this medication with caution due to potential increased risks.
Liver disease: Those afflicted with liver conditions need to be cautious, as it can exacerbate their condition.
Gastrointestinal Disease: Patients with GI disorders may need careful monitoring due to potential exacerbation of symptoms.
Pregnancy: The medicine could cause harm to the unborn child and is contraindicated in pregnant women.

Daily Dose

Your doctor will prescribe the daily dose of Mofetyl 500 Tablet. This can vary depending on your individual health factors and how your body responds to the medicine. It's very important to stick to the dose recommended by your doctor, and not to increase it without discussing it with them first.

Over Dose

Taking more than your prescribed dosage of Mofetyl 500 Tablet may lead to common side effects such as nausea, vomiting, or diarrhoea becoming more severe. If you think you've taken too much, consult your doctor for advice.

Missed Dose

If you forget to take a dose of Mofetyl 500 Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the one you missed and continue with your usual schedule. Never double up on doses without speaking to your doctor first.

Always store Mofetyl 500 Tablet at room temperature, ideally below 30 degrees Celsius.
Keep it in a dry place and protect it from light.
Make sure the medicine is kept out of reach of children.
It's crucial to use this medicine before the expiry date printed on the packaging.

Since Mofetyl 500 Tablet manages organ rejection following transplants, maintaining a healthy lifestyle is key. Regular exercise can help strengthen your body and immune system.
Have a balanced diet that includes plenty of fruits, vegetables, and lean protein. This can aid in recovery post-transplant and help your body cope with the immunosuppressive effects of the medication.

Fact Box

Drug Category	IMPDH Inhibitor
Therapeutic Category	Immunosuppressant
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Organ Rejection

What Is the Purpose of Mofetyl 500 Tablet?

Mofetyl 500 Tablet is an immunosuppressant medication designed to prevent the body's immune system from rejecting a transplanted organ.

How Does Mofetyl 500 Tablet Work?

It works by inhibiting the growth of specific cells in your immune system that can cause organ rejection after a transplant.

When should I take Mofetyl 500 Tablet?

You must take the medicine exactly as prescribed by your doctor.

What if I miss a dose of Mofetyl 500 Tablet?

If you miss a dose, take it as soon as you remember. However, if it's close to your next dose's time, skip the missed one.

Can I take over-the-counter medicines with Mofetyl 500 Tablet?

Always consult your doctor before combining other medicines with Mofetyl 500 Tablet as it can interact with certain medicines and reduce their effectiveness.

What are the possible side effects of Mofetyl 500 Tablet?

Common side effects include diarrhoea, nausea, vomiting and abdominal pain. Unusual symptoms or severe side effects should be reported to your doctor immediately.

Can pregnant women take Mofetyl 500 Tablet?

No, this medicine is contraindicated in pregnancy due to risks of fetal harm. Consult your doctor for alternatives if you're pregnant or planning to be.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

RPG House, 463, Dr. Annie Besant Road, Worli, Mumbai 400030

Country of origin: INDIA

References

Roxane Laboratories, Inc. (2001). Mycophenolate mofetil. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/065410s000lbl.pdf
Rx only. (n.d.). CellCept. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/050722s021,050723s019,050758s019,050759s024lbl.pdf
DailyMed - MYCOPHENOLATE MOFETIL capsule MYCOPHENOLATE MOFETIL tablet. (n.d.). https://www.dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=741e079a-646b-47ec-84ac-8e12574c2aaf&audience=consumer
Mycophenolate mofetil: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00688

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