Monotrate 30 Mg Tablet Sr 10

Monotrate Sr 30 Tablet 10

Sun Pharma Laboratories Ltd.

Strip of 10 Units

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₹6.68/Units

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Composition

Isosorbide-5-mononitrate / Isosorbide Mononitrate (30 Mg)

Strength:

60 MG 30 MG

Monotrate SR 30 Tablet is primarily used for the prevention of angina pectoris, a type of chest discomfort caused by coronary artery disease. It's part of a group of medications known as nitrates.

While this medicine's main use is to prevent angina attacks, it doesn't provide immediate relief during an acute attack. Its unique extended-release formulation allows for a steady release of the active ingredient throughout the day, making it effective for preventing such attacks when taken regularly.

You should take this medicine orally as directed by your doctor. Before you start using it, make sure you inform your doctor about any pre-existing conditions or ongoing medications. During its use, if you notice any side effects, immediately report to your doctor. It's important to continue taking this medicine for the duration prescribed by your doctor to get the best results.

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Monotrate SR 30 Tablet is used for the following:

Preventing angina pectoris: This medicine is used to help manage chest pain due to coronary artery disease.
Reducing oxygen demand in the heart: By relaxing and widening blood vessels, this medication helps decrease the workload of the heart, thus preventing angina attacks.
Sustained relief from angina symptoms: The extended-release formula offers long-term prevention against angina pectoris.

Directions for Use of Monotrate Sr 30 Tablet 10

Follow these instructions while taking Monotrate SR 30 Tablet:

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Monotrate SR 30 Tablet is taken orally.

Side Effects of Monotrate Sr 30 Tablet 10

Common side effects that might be experienced with Monotrate SR 30 Tablet include:

Headache
Dizziness
Lightheadedness
Nausea
Flushing

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Monotrate SR 30 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some tips for managing common side effects:

Headache: If you experience a headache, consult your doctor for advice on managing this side effect. Follow any recommendations provided by your doctor.
Nausea: Follow the dietary recommendations provided by your doctor.

Monotrate SR 30 Tablet contains isosorbide mononitrate (30 mg), which acts on your body in the following ways:

Stimulates Guanylate Cyclase: Isosorbide mononitrate stimulates an enzyme called guanylate cyclase in your body. This enzyme helps in increasing the production of cyclic guanosine monophosphate (cGMP), which is important for relaxing your blood vessels.
Lowers Blood Pressure: By increasing cGMP synthesis, isosorbide mononitrate effectively reduces your blood pressure.
Increases Oxygen Supply to Heart Muscle: This medicine also works by dilating (enlarging) coronary arteries and improving blood flow to areas of the heart that are not getting enough oxygen. This helps in reducing the workload on your heart and lowers its demand for oxygen, thus preventing anginal attacks.

Pregnancy

Caution is advised while taking Monotrate SR 30 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, the use of Monotrate SR 30 Tablet should be done under medical consultation. Discuss with your doctor to understand the potential risks and benefits.

Alcohol

Be cautious about consuming alcohol while on Monotrate SR 30 Tablet, as it may intensify the effects of low blood pressure. Always consult your doctor for guidance.

Liver

This medicine should be used with caution if you have severe liver problems. Your liver health should be discussed with your doctor before starting Monotrate SR 30 Tablet, as it may affect liver function.

Kidney

If you have any history of kidney problems, caution is recommended before using Monotrate SR 30 Tablet. It's a good idea to discuss these concerns with your doctor.

Using Machines & Driving

Dizziness or lightheadedness can occur while taking Monotrate SR 30 Tablet, which could affect your ability to drive or operate machinery. Ensure you know how this medicine affects you before engaging in such activities.

Allergy

Monotrate SR 30 Tablet is contraindicated if you are allergic to nitrates. If you know of any allergies you have, make sure to discuss this with your doctor before starting this medicine.

Children

Monotrate SR 30 Tablet should not be given to children under 18 years of age without medical consultation. Always consult your doctor before giving any medication to a child.

Older Patients

Older patients should take Monotrate SR 30 Tablet under medical supervision due to their susceptibility to its side effects. Caution is advised if patients are above 70 years of age who might also have liver and kidney issues. Your doctor will guide you based on your health status.

Interactions of Monotrate Sr 30 Tablet 10

Drug-Drug Interactions

Monotrate SR 30 Tablet interacts with the following medicines:

CYP-450 enzyme modifiers: Medicines like cimetidine, which affects liver metabolism, can increase the presence of the active ingredient in your system. On the other hand, enzyme inducers like rifampicin may decrease it.
PDE-5 inhibitors: Medicines for erectile dysfunction such as sildenafil can lead to a critical drop in blood pressure when taken along with Monotrate SR 30 Tablet.
Blood Pressure Medications: Taking this medication alongside antihypertensives, beta-blockers or calcium channel blockers could cause an excessive decrease in blood pressure.

Drug-Food Interactions

Monotrate SR 30 Tablet does not interact with food.

Drug-Disease Interactions

Monotrate SR 30 Tablet interacts with the following diseases:

Severe Anaemia: This medication should be used cautiously, as it could worsen the symptoms.
Hypotension: Patients with low blood pressure may experience further decreases when taking this medicine.
Hypertrophic Cardiomyopathy: Symptoms of this heart muscle disease may be exacerbated by this medication.

Daily Dose

Take the daily dose of Monotrate SR 30 Tablet as prescribed by your doctor. The dosage can change based on factors like the severity of your condition and how you respond to treatment. Always adhere to the prescribed dosage and avoid exceeding it without your doctor's advice.

Over Dose

Overdosing on Monotrate SR 30 Tablet could lead to symptoms such as extreme dizziness, nausea, and sweating. If you experience these symptoms persistently after taking more than the advised dosage, inform your doctor.

Missed Dose

If you forget to take Monotrate SR 30 Tablet at the usual time, take it as soon as you remember. If it's nearly time for your next dose, ignore the missed one and continue with your regular schedule. Don't increase your dose without consulting with your doctor.

Always store Monotrate SR 30 Tablet at room temperature, ideally between 15°C to 30°C.
Protect the tablets from moisture to maintain their effectiveness.
Keep this medicine out of the reach and sight of children.
Remember, it's vital to use this medication before its expiry date.

Since Monotrate SR 30 Tablet is used to manage angina, try to incorporate heart-healthy foods into your diet. This includes plenty of fruits, vegetables, whole grains and lean proteins such as fish and poultry.
Regular physical exercise can support heart health. However, always consult your doctor before starting a new exercise regimen.

Fact Box

Drug Category	Vasodilator
Therapeutic Category	Antianginal
Available Dosage Types	Tablet ER
Habit Forming	No
Ailment	Angina Pectoris, Coronary Artery Disease

What is Monotrate SR 30 Tablet used for?

It's used to prevent angina, a type of chest pain caused by heart disease. It's not for immediate relief during an angina attack.

How does Monotrate SR 30 Tablet work?

It relaxes and widens blood vessels, reducing the heart's workload and increasing oxygen supply, thereby preventing angina attacks.

Can I crush or chew Monotrate SR 30 Tablet?

No, you should swallow the tablet whole. Crushing or chewing it can impact the medicine's effectiveness.

Can I drink alcohol while taking this medicine?

You should avoid alcohol as it can increase the risk of low blood pressure, causing dizziness or fainting.

I missed a dose; should I take double next time?

No, take the missed dose as soon as you remember unless it's near the time for your next dose. Do not double up.

Can I use this medicine for immediate relief of chest pain?

No, this medicine is meant for long-term prevention of angina attacks, not immediate relief.

Is it safe to drive after taking Monotrate SR 30 Tablet?

Be cautious as the medicine may cause dizziness or lightheadedness. Avoid driving if you do not feel well.

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

SUN HOUSE CTS No. 201, 201, Western Express Hwy, Ram Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

References

monoket®. (2003). monoket® tablets. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020215s024lbl.pdf
DailyMed - ISOSORBIDE MONONITRATE tablet, extended release. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cd439861-2e23-4e0e-bcdc-48e2ebdc4943
NCATS Inxight Drugs — ISOSORBIDE MONONITRATE. (n.d.). https://drugs.ncats.io/substance/LX1OH63030
Isosorbide mononitrate: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01020

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