Nebula D 515 Mg Tablet Sr 10

Nebula D Tablet 10

Zydus Cadila

Strip of 10 Units

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MRP ~~₹245.2~~

₹201.06

₹24.52/Units

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Composition

Indapamide (1.5 Mg) + Nebivolol (5 Mg)

Nebula-D Tablet is typically used to manage hypertension, especially in patients who cannot adequately control their blood pressure with a single antihypertensive agent. This medicine belongs to a group of medications known as antihypertensives and is a combination medicine.

While the primary use of this medication is to manage hypertension, it can also be used for other health conditions as advised by your doctor. The medicine helps manage overall cardiovascular health by controlling blood pressure levels effectively.

The medicine should be taken orally as directed by your doctor. Before you begin taking this medicine, let your doctor know about any pre-existing conditions you have or any other medications you are currently taking. If you notice any side effects while taking this medication, inform your doctor immediately. For the best results, continue taking the medicine for the entire duration prescribed by your doctor.

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Nebula-D Tablet is used for the following:

Management of high blood pressure or hypertension that doesn't respond adequately to a single antihypertensive agent.

Directions for Use of Nebula D Tablet 10

Here are the instructions you should follow while taking Nebula-D Tablet:

Swallow the tablet whole with water, preferably at the same time each day.
Avoid crushing or chewing it.
Do not discontinue the medicine abruptly without discussing it with your doctor first.
For any specific advice, consult your doctor.

Nebula-D Tablet is taken orally.

Nebula-D Tablet may have the following common side effects:

Fatigue
Dizziness
Headache
Diarrhoea
Nausea
Hypokalaemia: This is a condition wherein your blood has lower-than-normal levels of potassium.
Hyponatraemia: This means your blood sodium levels are abnormally low.
Hyperglycemia: This refers to high blood sugar levels, which can occur with the intake of this medicine.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Nebula-D Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:

Headache: If a headache occurs after taking this tablet, consider taking it at bedtime to manage the discomfort.
Diarrhoea: Try taking Nebula-D Tablet with food or milk to lessen this effect.

Nebula-D Tablet is a combination medicine comprising two active ingredients that work together to manage hypertension effectively:

Indapamide (1.5 mg): This component is a thiazide-like diuretic, which works by increasing sodium and chloride excretion in a part of your kidneys called the distal convoluted tubule. This process leads to increased water removal from the body, helping reduce blood pressure.
Nebivolol (5 mg): This is a third-generation cardioselective beta-blocker with vasodilating properties. It selectively blocks beta-1 adrenergic receptors in your heart, reducing your heart rate and contractility. Nebivolol also stimulates the production of a substance called nitric oxide in the endothelium (inner lining) of your blood vessels, causing them to widen or dilate.

Pregnancy

Caution is advised while taking Nebula-D Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Nebula-D Tablet is excreted in human milk. It's recommended to avoid use during breastfeeding. Consult your doctor to understand the potential risks and benefits.

Alcohol

The interaction of Nebula-D Tablet with alcohol is unknown. It's advised to discuss your regular alcohol consumption with your doctor before starting this medication.

Liver

Caution is advised while taking Nebula-D Tablet in cases of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Nebula-D Tablet. This medicine may affect liver function.

Kidney

Caution is advised before using Nebula-D Tablet if you have a history of kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Nebula-D Tablet might cause dizziness or fatigue. If you experience these symptoms, avoid driving or operating heavy machinery until you feel normal again.

Allergy

If you are allergic to indapamide, nebivolol, or any other ingredients in Nebula-D Tablet, it's best to avoid taking it. Discuss any known allergies with your doctor.

Children

Nebula-D Tablet is not recommended for children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Nebula-D Tablet under medical supervision, as they may be more susceptible to its side effects. Caution is advised if patients are over 70 years of age. Older patients might also have liver and kidney issues and might be on other medications. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Nebula-D Tablet interacts with the following medicines:

NSAIDs: Medicines like ibuprofen and diclofenac may reduce the blood pressure lowering and diuretic effects of Nebula-D Tablet.
Digitalis Glycosides: Medicines like digoxin used for heart conditions could have increased toxicity due to the reduced potassium levels caused by Nebula-D Tablet.
Antimaniac Agents: Using lithium with Nebula-D Tablet can increase lithium levels in your body, heightening toxicity risk.
CYP2D6 Inhibitors: Certain medicines that inhibit CYP2D6 enzyme, like fluoxetine, can increase nebivolol levels in your body.
Calcium Channel Blockers: Medicines, such as amlodipine, can increase the risk of low blood pressure and heart failure when taken with Nebula-D Tablet.
Insulin and Oral Hypoglycemics: Medicines like insulin or metformin for diabetes could have reduced effects, leading to high sugar levels when taken with Nebula-D Tablet.

Drug-Food Interactions

None

Drug-Disease Interactions

Nebula-D Tablet interacts with the following diseases:

Serious kidney disease: Patients with severe renal impairment should exercise caution while taking Nebula-D Tablet as it can exacerbate their condition.
Sick sinus syndrome or heart block: People suffering from sick sinus syndrome or heart block should avoid using this medicine as it may worsen their condition.

Daily Dose

The daily dose of Nebula-D Tablet should be taken as advised by your doctor. The dosage might change depending on your condition's severity and how you respond to the treatment. Make sure to stick to the prescribed dosage and refrain from exceeding it without consulting your doctor. For more details, refer to the package insert.

Over Dose

Overdosing on Nebula-D Tablet may result in symptoms like severe low blood pressure, slow heart rate, and imbalance in bodily salts. If such symptoms appear, get in touch with your doctor without delay.

Missed Dose

If you happen to miss a dose of Nebula-D Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one now and continue with your regular schedule. It's crucial not to increase your dose without discussing it with your doctor first.

Store Nebula-D Tablet at room temperature, ideally between 15-30°C.
Protect your medicine from light and dampness to maintain its effectiveness.
Always keep Nebula-D Tablet out of reach of children to avoid accidental intake.
Remember to use the medicine before its expiration date for optimal results.

Reduce your salt intake: High sodium can raise blood pressure levels, counteracting Nebula-D Tablet's effectiveness in managing hypertension.
Engage in regular physical activity: Moderate exercise, such as walking or cycling, can help lower your blood pressure and improve the overall effectiveness of the Nebula-D Tablet. Please consult your doctor before starting any exercise regime.

Fact Box

Drug Category	Diuretic, Beta-Blocker
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Essential Hypertension

What is Nebula-D Tablet used for?

Nebula-D Tablet is used to manage hypertension that is not adequately controlled by a single antihypertensive medicine.

How does Nebula-D Tablet work in the body?

This medicine's active components, indapamide and nebivolol, decrease blood pressure by reducing blood volume and heart rate.

Can Nebula-D Tablet be taken with food?

You must take the medicine as directed by your doctor.

Are there any side effects of using Nebula-D Tablet?

Yes, some common side effects include electrolyte imbalances, slow heart rate (bradycardia), low blood pressure, and digestive issues.

Are there any precautions to consider while using Nebula-D Tablet?

Yes, people with severe liver or kidney problems, low potassium levels, and certain heart conditions should consult their doctor before using this medicine.

Can I suddenly stop taking Nebula-D Tablet?

No, abruptly stopping the medicine may lead to heart complications. Always consult your doctor before discontinuing any medication.

Can Nebula-D Tablet interact with other medicines?

Yes, it can interact with certain medications like NSAIDs, digitalis, lithium, and antidiabetic medications. Always inform your doctor about all the medicines you are currently taking.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

5V74+4P2, Jay Prakash Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

References

PubMed. (1999). [Effectiveness of indapamide in the treatment of hypertension]. Retrieved 1 April 2024, from https://pubmed.ncbi.nlm.nih.gov/10491730/
DailyMed. (n.d.). Indapamide tablet. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fecef8fc-b66b-4133-b66f-8d6b72750622
U.S. Food & Drug Administration. (n.d.). Indapamide prescribing information. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/psg/PSG_018538.pdf
U.S. Food & Drug Administration. (2007). Nebivolol hydrochloride (NDA 021742) approval letter. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/nda/2007/021742s000_LBL.pdf
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 3702, Indapamide. Retrieved November 19, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Indapamide

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