Nicostar 5 Mg Tablet 20

Nicostar 5 Tablet 20

Lupin Ltd

BOTTLE of 20 Units
BOTTLE of 30 Units

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MRP ~~₹328.5~~

₹269.37

₹16.43/Units

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Prescription required for this medicine

Store in refrigerator or (2^o - 8^o C) Do Not Freeze

Composition

Nicorandil (5 Mg)

Strength:

5 MG 10 MG

Nicostar 5 Tablet is commonly used for the prevention and long-term management of angina pectoris, a type of heart-related chest pain. It's part of a group of medicines known as potassium channel activators.

In addition to its primary use, this medicine can be beneficial when other antianginal medications are not sufficiently effective or cannot be taken. It provides relief by reducing the risk and frequency of angina attacks.

Before starting this medicine, it’s advisable to consult your doctor about the dosage and frequency. It's crucial to inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while taking this medicine, immediately let your doctor know. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

Nicostar 5 Tablet is used for the following:

Long-term and acute management of chronic stable angina pectoris not sufficiently controlled or intolerant to first-line antianginal therapies such as beta-blockers and calcium channel blockers
Prevention of angina pectoris episodes, a condition characterised by heart-related chest pain

Directions for Use of Nicostar 5 Tablet 20

Here are the instructions to follow while taking Nicostar 5 Tablet:

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Nicostar 5 Tablet is taken orally.

Nicostar 5 Tablet may have the following common side effects:

Headache
Dizziness
Flushing
Nausea
Vomiting
Weakness
Palpitations

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve by discontinuing the use of Nicostar 5 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Follow the dietary recommendations provided by your doctor.
Dizziness: Avoid activities your doctor has advised against and follow their recommendations.

Nicostar 5 Tablet contains Nicorandil (5 MG), which works within the body as follows:

Opens ATP-sensitive Potassium Channels: Nicorandil functions by increasing potassium ion permeability; it opens up ATP-sensitive potassium channels leading to vascular smooth muscle relaxation and vasodilation in the coronary arteries.
Stimulates Guanylate Cyclase: Nicorandil acts similarly to nitrates by stimulating guanylate cyclase and increasing intracellular cyclic GMP (cGMP). This process causes vasodilation of both arterial and venous vessels.

Pregnancy

You should avoid taking Nicostar 5 Tablet if you are pregnant due to the potential for harm to the foetus. It is best to consult your doctor before taking this medicine.

Breastfeeding

Nicostar 5 Tablet should be avoided during breastfeeding. Consult your doctor to understand the potential risks and benefits.

Alcohol

Be aware that alcohol can enhance the blood pressure-lowering effects of Nicostar 5 Tablet. It's advisable to limit your alcohol intake while using this medicine.

Liver

If you have mild to moderate liver problems, caution is advised when taking Nicostar 5 Tablet. It's recommended to discuss your health status with your doctor before starting this medication.

Kidney

This medicine doesn't require dose adjustment in patients with kidney disease. However, if you have a history of kidney problems, it's wise to consult your doctor before starting Nicostar 5 Tablet.

Using Machines & Driving

Nicostar 5 Tablet may cause dizziness and lightheadedness. Avoid driving or operating heavy machinery if you experience these symptoms after taking this medicine.

Allergy

If you are allergic to Nicorandil or any other ingredients in Nicostar 5 Tablet, avoid using this medication. Inform your doctor about any known allergies.

Children

Nicostar 5 Tablet is not recommended for use in children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Nicostar 5 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Nicostar 5 Tablet interacts with the following medicines:

Antihypertensives: Medicines like amlodipine or lisinopril can further lower blood pressure when taken with Nicostar 5 Tablet, leading to hypotension.
Vasodilators: Medicines such as hydralazine or isosorbide mononitrate can interact with Nicostar 5 Tablet, potentially enhancing its vasodilatory effects and causing hypotension.
Phosphodiesterase-5 inhibitors: Medicines like sildenafil, tadalafil, and vardenafil used for erectile dysfunction can interact with Nicostar 5 Tablet, significantly amplifying its blood pressure lowering effect.

Drug-Food Interactions

There are no specific food interactions known for Nicostar 5 Tablet.

Drug-Disease Interactions

Nicostar 5 Tablet interacts with the following diseases:

Hypertension: As Nicostar 5 Tablet lowers blood pressure, it should be used cautiously in patients with hypertension.
Hypotrophic Obstructive Cardiomyopathy (HOCM): This medicine may worsen angina in patients with HOCM due to its vasodilatory effect.
Ulcers: Patients suffering from gastrointestinal tract ulcers, skin ulcers, or mucosa ulcers should avoid using Nicostar 5 Tablet as it has been reported to exacerbate these conditions.

Daily Dose

Nicostar 5 Tablet should be taken as per the dosage prescribed by your doctor. This dosage may differ based on factors like the severity of your condition and how you respond to the medicine. Always adhere to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you accidentally take more Nicostar 5 Tablets than prescribed, you may experience symptoms such as feeling weak, light-headedness, and a fast heartbeat. If such symptoms persist, inform your doctor promptly.

Missed Dose

If you forget to take a dose of Nicostar 5 Tablet, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Don't increase your dosage without consulting your doctor.

Keep Nicostar 5 Tablet in a dry place, protected from light.
Maintain an ideal storage temperature between 2°C to 8°C.
Don't free the medicine.
Always keep this medicine out of reach of children.
Ensure you use Nicostar 5 Tablet before the expiry date indicated on the package.

Regular physical activity is key; it helps improve blood flow, which can reduce symptoms of angina. However, please consult your doctor for suitable exercises and their duration.
Reduce your intake of saturated fats and cholesterol-rich foods to maintain good heart health; these can lead to blocked arteries, and worsening angina symptoms.

Fact Box

Drug Category	Potassium Channel Activator
Therapeutic Category	Antianginal Medicine
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Angina Pectoris, Chronic Stable Angina

What Is Nicostar 5 Tablet?

Nicostar 5 Tablet is a medicine containing nicorandil that helps manage angina pectoris, a type of chest pain related to the heart.

How Does Nicostar 5 Tablet Work?

This medicine works by widening blood vessels, reducing strain on the heart, and improving blood flow, thus helping to prevent angina attacks.

Can I take Nicostar 5 Tablet with food?

You must take the medicine exactly as prescribed by your doctor.

Are there any side effects of Nicostar 5 Tablet?

Common side effects include headache, dizziness, flushing, nausea, vomiting and palpitations. Consult your doctor if these persist or worsen.

Who should not take Nicostar 5 Tablet?

If you have severe low blood pressure, acute pulmonary oedema, or are allergic to nicorandil or any other ingredients in the medicine, avoid taking it.

Can I stop taking Nicostar 5 Tablet once I feel better?

No, abruptly stopping can worsen your angina symptoms. Always consult your doctor for advice on discontinuation.

Can I consume alcohol while taking the Nicostar 5 Tablet?

Alcohol can increase the blood pressure-lowering effects of this medicine and should ideally be avoided.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

References

AUSTRALIAN PRODUCT INFORMATION – IKOREL (NICORANDIL). (2020). In Ikorel-ccdsv10-piv16-18sep20 (pp. 1–13). https://apps.medicines.org.au/files/swpikore.pdf
Nicorandil: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09220
PubChem. (n.d.). Nicorandil. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Nicorandil
Zhang, Y., Wang, X., Liu, R., Li, Q., Tian, W., Lei, H., & Shi, C. (2021). The effectiveness and safety of nicorandil in the treatment of patients with microvascular angina. Medicine, 100(2), e23888. https://doi.org/10.1097/md.0000000000023888
Ahmed, L. (2019). Nicorandil: A drug with ongoing benefits and different mechanisms in various diseased conditions. Indian Journal of Pharmacology/the Indian Journal of Pharmacology, 51(5), 296. https://doi.org/10.4103/ijp.ijp_298_19

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