Nucoxia Pg 7560 Mg Tablet Pr 10

Nucoxia Pg Tablet 10

Zydus Cadila

Strip of 10 Units

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MRP ~~₹275.85~~

₹226.20

₹27.59/Units

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Composition

Etoricoxib (60 Mg) + Pregabalin (75 Mg)

Nucoxia PG Tablet is primarily used to manage neuropathic pain conditions. It's a combination medicine that belongs to the class of NSAIDs and anticonvulsants.

In addition to its principal use, this medicine is also employed for managing painful conditions like diabetic neuropathy, post-herpetic neuralgia, trigeminal neuralgia, and central neuropathic pain. The combination of ingredients in this medicine works together to provide effective pain relief.

To ensure optimal results from this medicine, it's essential to take it as directed by your doctor. Before starting the medication, you should inform your doctor about any pre-existing conditions or other medications you're on. If you notice any side effects while using this medicine, alert your doctor immediately. It's crucial to continue taking the medicine for the duration prescribed by your doctor.

Nucoxia PG Tablet is used for the following:

Managing neuropathic pain conditions
Providing relief from painful diabetic neuropathy
Reducing discomfort in post-herpetic neuralgia
Alleviating pain related to trigeminal neuralgia
Managing central neuropathic pain

Directions for Use of Nucoxia Pg Tablet 10

Here's how you should take Nucoxia PG Tablet:

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Nucoxia PG Tablet is taken orally.

Nucoxia PG Tablet may have the following side effects:

Dizziness
Drowsiness
Dry Mouth
Headache
Nausea
Peripheral Oedema: This is when you experience swelling in your limbs, especially in your legs, ankles, and feet.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Nucoxia PG Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Dizziness: If you experience dizziness, consult your doctor for advice on managing this side effect. Avoid activities your doctor has advised against and follow their recommendations.
Nausea: Follow the diet plan recommended by your doctor.

Nucoxia PG Tablet contains two active ingredients:

Etoricoxib (60 mg): This component selectively inhibits an enzyme called cyclooxygenase-2 (COX-2). The enzyme plays a key role in producing prostaglandins, which cause inflammation and pain. By blocking COX-2, etoricoxib effectively reduces inflammation and pain.
Pregabalin (75 mg): This ingredient works by attaching itself to specific sites in the nervous system, which control the release of certain neurotransmitters that send pain signals. By doing so, pregabalin reduces the level of these neurotransmitters, decreasing the intensity of pain signals reaching the brain.

Pregnancy

Nucoxia PG Tablet is not recommended during pregnancy, particularly in the third trimester. If you are pregnant or planning to conceive, ensure to discuss this with your doctor before starting this medicine.

Breastfeeding

Nucoxia PG Tablet is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Alcohol may enhance certain side effects of Nucoxia PG Tablet such as drowsiness and dizziness. It's best to avoid alcohol while taking this medicine.

Liver

Caution is advised while taking Nucoxia PG Tablet in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Nucoxia PG Tablet. This medicine may affect liver function.

Kidney

Caution is advised before using Nucoxia PG Tablet if you have a history of kidney problems. It is advisable to consult your doctor before taking this medicine.

Using Machines & Driving

Nucoxia PG Tablet may cause dizziness or drowsiness. Exercise caution when driving or operating machinery until you know how this medicine affects you.

Allergy

If you are allergic to Etoricoxib or Pregabalin, or any other components of Nucoxia PG Tablet, it's best not to take this medicine. Always inform your doctor about any allergies before starting a new medication.

Children

Caution is advised while giving Nucoxia PG Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Nucoxia PG Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Nucoxia PG Tablet interacts with the following medicines:

CYP3A4 Inhibitors: Medicines like ketoconazole and itraconazole can increase the exposure of etoricoxib, one of the ingredients in Nucoxia PG Tablet, as it is metabolised by CYP3A4.
Anticoagulants or Antiplatelet Agents: Warfarin and clopidogrel may increase the risk of bleeding when used with Nucoxia PG Tablet due to the presence of etoricoxib.
CNS Depressants: The effect of diazepam and fluoxetine can be enhanced by pregabalin, an ingredient in the tablet.
Thiazolidinediones: When combined with Nucoxia PG Tablet, there might be an increased risk of peripheral oedema and weight gain due to pregabalin.

Drug-Food Interactions

There are no known specific food interactions with Nucoxia PG Tablet.

Drug-Disease Interactions

Nucoxia PG Tablet interacts with the following diseases:

Cardiovascular Disease: This medicine should be used with caution if you have a history of cardiovascular disease due to the presence of etoricoxib.
Cerebrovascular Disease: If you have a history of cerebrovascular disease, taking this medicine might require additional caution.
Renal or Hepatic Impairment: Dose adjustments might be necessary if you have renal or hepatic impairment.

Daily Dose

The daily dose of Nucoxia PG Tablet should be taken as advised by your doctor. The dosage can vary based on individual factors, such as the severity of the condition and response to treatment. Sticking to the prescribed dosage and not increasing it without consulting your doctor is crucial.

Over Dose

An overdose of Nucoxia PG Tablet might lead to common side effects like dizziness, sleepiness, and dry mouth becoming more intense. If you suspect an overdose, inform your doctor promptly.

Missed Dose

In case you forget to take a dose of Nucoxia PG Tablet, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed one and continue with your usual schedule. Never double up your dose without consulting your doctor.

Store your Nucoxia PG Tablet at room temperature, ideally between 15-30°C.
Keep it in a dry place, away from direct sunlight and moisture.
It's essential to keep this medicine out of reach of children.
Always check the expiry date on the pack before use.

If you're managing neuropathic pain with Nucoxia PG Tablet, consider incorporating gentle exercises into your routine. Activities like walking or yoga can help improve circulation and reduce pain.
A diet rich in fruits, vegetables, lean proteins, and whole grains can support overall well-being. Remember to stay hydrated as well. This can help manage symptoms of neuropathy and contribute to general health. Always consult your doctor for specific dietary advice.

Fact Box

Drug Category	COX-2 Inhibitor, Anticonvulsant
Therapeutic Category	Anti-inflammatory, Analgesic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Diabetic Neuropathy, Neuralgia

What Is Nucoxia PG Tablet?

Nucoxia PG Tablet is a medicine combining etoricoxib and pregabalin, used to manage neuropathic pain conditions such as diabetic neuropathy and post-herpetic neuralgia.

How Does Nucoxia PG Tablet Work?

Etoricoxib in Nucoxia PG Tablet helps reduce pain and inflammation, while pregabalin works by modulating pain signals, together managing neuropathic pain effectively.

Can I Crush or Chew the Nucoxia PG Tablet?

No, you should swallow the tablet whole without crushing, chewing, or splitting. It's designed for a slow release of active ingredients.

Can I Take Nucoxia PG Tablet if I'm Pregnant or Breastfeeding?

It's not recommended to take Nucoxia PG Tablet during pregnancy or while breastfeeding due to potential risks. Always consult your doctor before taking this medicine.

What Are the Possible Side Effects of Taking Nucoxia PG Tablet?

Common side effects may include dizziness, drowsiness, dry mouth, constipation, and peripheral oedema. Rare serious side effects can also occur.

What Should I Do If I Overdose on Nucoxia PG Tablet?

If you suspect an overdose, seek immediate medical assistance. Overdose may result in severe adverse effects requiring supportive treatment.

How Should I Store My Nucoxia PG Tablet?

Keep your tablets at room temperature (15-30°C), in a dry place protected from light and moisture. Ensure they are out of children's reach.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

5V74+4P2, Jay Prakash Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

References

Pregabalin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00230
Etoricoxib: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01628
The effect of Pregabalin and etoricoxib on pain alone versus in combination - Full text view - ClinicalTrials.gov. (n.d.). https://classic.clinicaltrials.gov/ct2/show/NCT06401499
Yeole, A. B., Lakshmi, G. S. R., Selvakumar, C. J., Goni, V. G., Nawal, C. L., Valya, B. J., Patel, B. J., Patel, R. D., Pawar, E. D., Panigrahi, R., Kumar, A. Y., Shintre, S. S., Devkare, P. H., Dharmadhikari, S. K., Choudhari, S. Y., Doshi, M. S., Mehta, S. C., & Joglekar, S. J. (2022). Efficacy and safety of Pregabalin Prolonged Release–Etoricoxib combination compared to Etoricoxib for Chronic low back pain: Phase 3, randomized study. Pain and Therapy, 11(4), 1451–1469. https://doi.org/10.1007/s40122-022-00437-2

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