Pangraf 0.5 Capsule 10

PanGraf 0.5 Capsule is used in adults to prevent the body's immune system from rejecting a transplanted kidney, liver or heart, and is usually given together with other immunosuppressant medicines.

Uses of PanGraf 0.5 Capsule are:

• Kidney Transplant: Helps prevent rejection after a kidney transplant.
• Liver Transplant: Supports the body's acceptance of a newly transplanted liver.
• Heart Transplant: Helps the body accept a transplanted heart.

Here's how to take PanGraf 0.5 Capsule correctly:

• Follow the dosage and timing instructions provided by your doctor precisely.
• Do not change or exceed the prescribed dose without consulting your doctor.
• Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
• Adhere to the dietary recommendations given by your doctor.

PanGraf 0.5 Capsule is taken orally.

PanGraf 0.5 Capsule contains tacrolimus (0.5 mg), which acts on your body as follows:

• T-Lymphocyte Inhibition: Tacrolimus operates by inhibiting T-lymphocyte activation. These T-lymphocytes are components of your immune system that can potentially lead to organ rejection.
• Calcineurin Phosphatase Inhibition: By forming a complex with an intracellular protein called FKBP-12, tacrolimus obstructs the action of calcineurin phosphatase. This process reduces the production of certain substances known as IL-2 and IFN-gamma that promote T-cell activation and proliferation.
• Immune Response Reduction: The overall effect of these actions is that tacrolimus lowers your body's ability to mount an immune response against the transplanted organ, thereby aiding in its acceptance and reducing the risk of rejection.

• Store PanGraf 0.5 Capsule at a controlled room temperature below 30°C.
• Keep it protected from moisture and light, in its original container.
• Always keep this medicine out of reach of children.
• Ensure to use the medicine before its expiry date.

• As an immunosuppressant, PanGraf 0.5 Capsule might increase your risk of skin cancer. So always use good quality sunscreen and wear protective clothing when you go outdoors.
• Since this medication may affect your sugar levels, monitor your blood sugar regularly and maintain a balanced diet that's low in sugar and high in fibre.