Phexin Capsule 10

Here are some drug-drug interactions to be cautious of

• Antibiotics: Phexin 500 mg capsule may interact with other antibiotics such as capreomycin, vancomycin, gentamicin, neomycin, tobramycin, and cefuroxime. The concomitant use of these antibiotics with a Phexin 500 mg capsule may increase the risk of nephrotoxicity and ototoxicity. Therefore, when taking these medications together, blood sugar and kidney function monitoring is recommended.
• Antidiabetic: Phexin 500 mg capsule may interact with antidiabetic medications such as metformin. The concomitant use of Phexin 500 mg capsule with metformin may raise the risk of lactic acidosis, a rare but severe side effect. Therefore, blood sugar and kidney function monitoring is recommended when taking these medications together.
• Diuretics: Phexin 500 mg capsule may interact with diuretics such as furosemide and bumetanide. The concomitant use of Phexin 500 mg capsule with these diuretics may increase the risk of kidney toxicity. Therefore, monitoring kidney function regularly when taking these medications together is essential.
• Oral anticoagulants: Medication such as warfarin may prolong prothrombin time when combined with cephalosporins. 
• Typhoid vaccine: Antibacterial activity against salmonella typhi organisms may interfere with the immunological response to the live typhoid vaccine. The appropriate time should elapse between the administration of the last dose of the antibiotic and the live typhoid vaccine.

There are no notable drug-food interactions with Phexin 500 mg capsule. However, when using Phexin 500 mg capsule, the following drug-food interactions have been documented:

• Grapefruit juice: Along with Phexin 500 mg capsule, grapefruit juice may interact with other medications a person may be taking. Due to the presence of chemicals in grapefruit juice, some drugs may not be adequately metabolised, resulting in higher blood levels and a higher risk of adverse effects.
• Zinc Supplements: Zinc can reduce cephalexin absorption in the body. As a result of this, cephalexin may become less effective in fighting infections. Separating zinc and cephalexin can prevent this interaction. Taking zinc or zinc-containing multivitamins at least 3 hours after taking cephalexin helps your body absorb it better. 

Additionally, taking the Phexin 500 mg capsule with food is suggested to lower the possibility of gastrointestinal side effects. 

There are certain disease conditions in which the use of Phexin 500 mg capsule may not be safe, or caution is required.

• Colitis: Colitis is the inflammation of the colon's lining. Antibiotics such as Phexin 500 mg capsule can disrupt the normal gut flora, leading to an overgrowth of harmful bacteria like Clostridium difficile. This can cause a type of colitis called antibiotic-associated colitis or pseudomembranous colitis. Patients with a history of colitis or diarrhoea should use Phexin 500 mg capsule judiciously.
• Seizure disorders: Patients with a history of seizure disorders such as epilepsy should use Phexin 500 mg capsule carefully, as it can lower the seizure threshold and raise the likelihood of seizures.
• Dialysis: Phexin 500 mg capsule is mainly excreted by the kidneys. Patients with severe kidney dysfunction, including those on dialysis, should use the Phexin 500 mg capsule cautiously under the guidance of a healthcare provider.
• Kidney and liver dysfunction: Patients with pre-existing kidney or liver dysfunction should use Phexin 500 mg capsule cautiously, as it can worsen the condition.

The recommended daily dose of Phexin 500 mg capsule is once daily, with food, as directed by your doctor. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is essential to follow the suggested dosage and not exceed it without consulting your doctor. 

If you or someone else takes excessive Phexin 500 mg capsules by accident, it is essential to take immediate medical attention from your doctor or nearby hospital. An overdose's symptoms include brain damage and may cause headache, dizziness and stomach upset.

If you forgot to take the Phexin 500 mg capsule, take it as soon as you recall or contact your healthcare provider. If the time for the next dosage is close, skipping the missed one is recommended now and resume your regular dosage pattern. Never increase your dosage without consulting your doctor.