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Pipzo 4.5g Injection 1
Alkem Laboratories Ltd.
Vial of 1 UNITS
MRP ₹342.01
₹273.61
₹342.01/UNITS
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Uses of Pipzo 4.5g Injection 1
Pipzo 4.5g Injection is used in the following conditions:
- Intra-abdominal bacterial infections: This injection is employed to treat infections within the abdominal cavity caused by a range of susceptible bacteria, helping to reduce infection.
- Skin and skin structure bacterial infections: This injection also addresses bacterial infections of the skin, subcutaneous tissue, and soft tissue.
- Female pelvic infections: This injection also helps treat female pelvic infections in adults, also known as pelvic inflammatory disease (PID). It is a bacterial infection that affects the female reproductive organs, including the uterus, fallopian tubes, and ovaries.
- Community-acquired and hospital-acquired pneumonia: This injection is also employed to relieve respiratory symptoms due to community-acquired and hospital-acquired pneumonia.
Directions for Use of Pipzo 4.5g Injection 1
- A healthcare professional should administer Pipzo 4.5g Injection under the supervision of a doctor. It is not recommended to be self-administered.
- If you have any concerns or questions about the timing or dosage of this injection, please consult your doctor.
Route of Administration
Pipzo 4.5g Injection is given intravenously.
Side Effects of Pipzo 4.5g Injection 1
The common side effects of Pipzo 4.5g Injection include:
- Diarrhoea
- Constipation
- Nausea
- Headache
- Insomnia
Managing the Side Effects:
Most of the side effects resolve on discontinuation of the injection and are temporary and, in the majority of cases, do not require medical attention. If you experience severe or persistent side effects from this injection, consult your doctor.
How Pipzo 4.5g Injection 1 Works?
Pipzo 4.5g Injection contains the following components:
- Piperacillin (4000 mg): It is a broad-spectrum antibiotic that inhibits the formation of bacterial cell walls. It interferes with the enzymes responsible for building the bacterial cell wall, weakening and eventually rupturing it.
- Tazobactam (500 mg): It is a beta-lactamase inhibitor that works by inhibiting the enzymes produced by bacteria that can break down certain types of antibiotics, such as penicillins and cephalosporins. By inhibiting these enzymes, tazobactam helps piperacillin to be more effective against bacteria that may produce beta-lactamase enzymes and are resistant to other types of antibiotics.
Safety Measures & Warnings
Pregnancy
Pipzo 4.5g Injection can cross the placenta in humans. However, there is no reliable information on the risk of birth defects and miscarriage due to this injection. If you are pregnant, it is recommended to inform your doctor when this injection is prescribed to you.
Breastfeeding
Breastfeeding women should cautiously take Pipzo 4.5g Injection. It passes into breast milk. Before taking this injection while breastfeeding, it is recommended to consult your doctor.
Alcohol
Alcohol is not recommended after receiving Pipzo 4.5g Injection. It can worsen the side effects of this injection.
Liver
Patients with liver disease can safely take Pipzo 4.5g Injection. No dose adjustment is required in these patients. Still, you should inform your doctor if you have severe liver disease before taking this injection.
Kidney
Pipzo 4.5g Injection should be cautiously administered in patients with kidney disease or those undergoing dialysis. Dose adjustments may be required for such patients. If you have a severe kidney problem, inform your doctor before taking this injection.
Using Machines & Driving
Pipzo 4.5g Injection is unlikely to affect your mental or physical abilities required for using machines or driving. However, avoiding attentive tasks is recommended if you experience any side effects after receiving the injection.
Allergy
Do not take Pipzo 4.5g Injection if you have a history of allergic reactions to penicillins, cephalosporins, or beta-lactamase inhibitors. Read the label and check the ingredients before taking this injection to avoid allergic reactions.
Children
Pipzo 4.5g Injection is not intended for children under two months of age. For children aged two months and older, it is advised to consult your doctor for the appropriate dosage to be administered.
Older Patients
Older patients with kidney dysfunction should take this injection cautiously. They may also take other medications that can interact with this injection. Inform your doctor and discuss your prescription medications before taking Pipzo 4.5g Injection.
Interactions of Pipzo 4.5g Injection 1
Drug-Drug Interactions
Pipzo 4.5g Injection can interact with medications, including:
- Other antibiotics, such as vancomycin and tobramycin. This injection can reduce the concentration of tobramycin in blood. The concomitant use of vancomycin may increase the incidence of acute kidney damage.
- Antigout medications such as probenecid. It extends the time that this injection remains active in the body.
- Muscle relaxants such as vecuronium. This injection can potentially extend the effects of vecuronium.
- Heparin or oral blood clotting medications. Monitoring of coagulation parameters is required while taking this injection.
Drug-Disease Interactions
Pipzo 4.5g Injection can interact with diseases, including:
- Severe diarrhoea: This injection may worsen existing diarrhoea.
- Hypokalaemia or low potassium levels in the blood: Hypokalaemia may occur in patients with low potassium reserves.
- Kidney impairment: This injection is excreted through the kidneys. Dose adjustment may be required in kidney patients.
- Cystic fibrosis: Patients with cystic fibrosis should cautiously take this injection due to the risk of fever and rashes.
Dosage of Pipzo 4.5g Injection 1
Daily Dose
Take Pipzo 4.5g Injection as directed by your doctor. The dosage may vary with the severity of the condition and response to treatment.
Over Dose
If you take an excessive amount of Pipzo 4.5g Injection by accident, it is essential to get immediate medical attention from your doctor or nearby hospital. Symptoms of an overdose include nausea, vomiting, and diarrhoea.
Missed Dose
Your doctor will provide the instructions on when to give you this injection. It is unlikely that you will not be given the medicine as it has been prescribed. However, if you think you missed a dose, tell your doctor.
Storage
- Store this injection at a temperature below 25 ºC.
- Protect it from light.
- Do not use this injection after the expiry date has passed.
Diet and Lifestyle Advice
- Maintain good hygiene practices, including regular handwashing, to prevent the spread of infections.
- Minimise or avoid alcohol consumption, as it can weaken the immune system and hinder healing.
- If you're contagious, avoid close contact with others to prevent the spread of the infection.
Fact Box
| Drug Category | Ureidopenicillins and beta-lactamase inhibitors |
| Therapeutic Category | Antibiotics |
| Available Dosage Types | Injection |
| Habit Forming | No |
| Ailment | Bacterial infections including intra-abdominal infections, skin and skin structure infections, female pelvic infections, community-acquired pneumonia, and nosocomial pneumonia |
Frequently Asked Questions (FAQs)
Is Pipzo 4.5g Injection an antibiotic?
This injection is an antibiotic used to treat bacterial infections, including intra-abdominal infections, skin infections, female pelvic infections, community-acquired pneumonia, and nosocomial pneumonia.
What is the contraindication of Pipzo 4.5g Injection?
This injection is contraindicated in individuals with kidney impairment, cystic fibrosis, and severe diarrhoea.
Is Pipzo 4.5g Injection safe for kidneys?
This injection should be used cautiously in patients with kidney problems, and the dosage may need adjustment based on kidney function. If you have kidney impairment, inform your doctor while this injection is prescribed to you.
Is Pipzo 4.5g Injection used alone or in combination?
This injection is typically used in combination with other antibiotics for treating various bacterial infections, and it is not commonly administered as a standalone treatment. The specific combination and dosage depend on the type and severity of the bacterial infection being treated.
What is the duration of treatment with Pipzo 4.5g Injection?
The duration of this injection treatment varies depending on the type and severity of the infection. However, it's typically administered over several days to a few weeks.
What type of bacteria does Pipzo 4.5g Injection treat?
This injection provides coverage against a wide range of bacteria, such as staphylococcus aureus, escherichia coli, klebsiella pneumoniae, pseudomonas aeruginosa, and many others susceptible to piperacillin and tazobactam.
Is Pipzo 4.5g Injection safe for liver disease?
This injection is safe in individuals with liver disease. No dose adjustments may be required for liver patients. However, consultation with a doctor is advised to ensure safe and appropriate administration in patients with liver disease.
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References
- ZOSYN ® (piperacillin and tazobactam) for injection, for intravenous use ZOSYN ® (piperacillin and tazobactam) injection, for intravenous use. (n.d.). Fda.Gov. (Retrieved October 2023). https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/050684s88s89s90_050750s37s38s39lbl.pdf
- PIPERACILLIN AND TAZOBACTAM FOR INJECTION Only. (n.d.). Fda.Gov. (Retrieved October 2023). https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/065386lbl.pdf
- Piperacillin/tazobactam 4g/0.5g Powder for Solution for Infusion - Summary of Product Characteristics (SmPC) - (emc). (n.d.). Org.uk. (Retrieved October 2023). https://www.medicines.org.uk/emc/product/6526/smpc
- Conan MacDougall (2018).Penicillins, Cephalosporins, and Other β-Lactam Antibiotics. In Goodman & Gilman’s: The Pharmacological Basis of Therapeutics (13th ed., pp.1030). essay, McGraw Hill Medical.
- Tripathi, K. D. (2019). Beta-Lactam Antibiotics. In Essentials of Medical Pharmacology (8th ed., pp. 774-775). essay, Jaypee Brothers Medical Publishers.
- TAZACT Injection. (n.d.). CiplaMed. (Retrieved October 2023). https://ciplamed-library.com/content/tazact-injection
- CDSCO. (n.d.). Gov.In. (Retrieved October 2023). https://cdscoonline.gov.in/CDSCO/Drugs
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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Registered Office Address
Intellihealth Solutions Private Limited
Office Unit no. 1, 2, 5, & 7, 6th floor Urmi Corporate Park Solaris, Saki Vihar Rd, Opp. L&T Flyover, New Mhada Colony, Budhia Jadhav Wadi, Mumbai, Maharashtra 400072.
CIN: U85320MH2019PTC320566
Telephone:09240250346
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