Planep 50 Tablet 15

Lupin Ltd

STRIP of 15 Units
STRIP of 10 Units

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MRP ~~₹820.9~~

₹656.72

₹54.73/Units

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Composition

Eplerenone (50 Mg)

Strength:

25 MG 50 MG

Planep 50 Tablet is primarily employed to manage hypertension and heart failure. This medicine is a solo-ingredient formulation, falling under the category of potassium-sparing diuretics.

Besides controlling high blood pressure, it plays a significant role in managing heart failure, particularly post-heart attack, to enhance survival chances and lower the likelihood of cardiovascular hospitalisation.

It's crucial to take this medicine as directed by your doctor. Before starting the course, inform your doctor about any pre-existing health conditions or ongoing medicines you are on. If you experience any side effects while on this medicine, promptly notify your doctor. Ensure you continue taking the medicine for the duration prescribed by your doctor for optimised results.

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Planep 50 Tablet is used for the following:

Managing mild to moderate high blood pressure
Assisting in improving survival and reducing hospitalisation related to heart failure, particularly after a heart attack

Directions for Use of Planep 50 Tablet 15

Here's how you should take Planep 50 Tablet:

Swallow the tablet whole with a glass of water.
Avoid crushing, chewing or breaking the tablet.
If you're feeling well, don't stop taking this medicine until you've consulted your doctor.

Planep 50 Tablet is taken orally.

Planep 50 Tablet may have the following side effects:

Dizziness
Headache
Fatigue
Nausea
Increased urination
Hyperkalaemia: This is a condition where there is too much potassium in your blood, which can cause irregular heartbeat or a tingly feeling in your muscles.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Planep 50 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Dizziness: Try taking Planep 50 Tablet before bedtime to minimise this effect during your daily activities.
Increased urination: If this becomes inconvenient, consider taking this medicine early in the day to avoid disrupting your sleep pattern at night.

Planep 50 Tablet contains Eplerenone (50mg). The medicine works in the following ways:

Aldosterone Blockade: Eplerenone obstructs the action of aldosterone, a hormone that contributes to increased blood pressure and heart failure. By blocking aldosterone, it helps decrease blood pressure.
Enhanced Kidney Function: The medicine aids the kidneys in getting rid of excess water and sodium from the body while retaining potassium. This leads to a reduction in fluid volume and blood pressure, easing the load on the heart.

Pregnancy

Planep 50 Tablet may harm the unborn baby. If you are pregnant or planning to conceive, it is best to consult your doctor before using this medicine.

Breastfeeding

It is not known if Planep 50 Tablet passes into breast milk. Nursing mothers should consult with their doctor before starting this medication.

Alcohol

Combining alcohol with Planep 50 Tablet may increase the likelihood of dizziness. It's a good idea to limit alcohol consumption while taking this medicine.

Liver

This medicine may affect liver function. If you have liver problems, discuss them with your doctor before starting Planep 50 Tablet.

Kidney

Planep 50 Tablet is contraindicated for patients with severely impaired kidney function. If you have kidney problems, it's best to consult your doctor before taking this medicine.

Using Machines & Driving

Planep 50 Tablet can cause dizziness which may affect your ability to drive or operate machinery. Be cautious until you know how the medication affects you.

Allergy

If you are allergic to eplerenone or any other ingredients in Planep 50 Tablet, do not take this medicine. Always inform your doctor about any allergies before starting a new medication.

Children

Planep 50 Tablet is not intended for use in children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Planep 50 Tablet under medical supervision as they may be more susceptible to its side effects and may have liver or kidney issues. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Planep 50 Tablet interacts with the following medicines:

Potassium supplements or potassium-sparing diuretics: Consuming these alongside Planep 50 Tablet may increase the risk of high potassium levels in your blood, known as hyperkalaemia. Some examples include amiloride, spironolactone, and triamterene.
ACE inhibitors or angiotensin receptor blockers (ARBs): These can also elevate your potassium levels when taken with Planep 50 Tablet. Examples are enalapril and losartan.
NSAIDs: When taken with Planep 50 Tablet, NSAIDs like ibuprofen and naproxen can reduce the diuretic effect and potentially increase the risk of kidney problems.
Lithium: Consuming lithium while on Planep 50 Tablet may increase lithium levels in your body, leading to toxicity.
CYP3A4 inhibitors: These can increase eplerenone levels in your body, thereby heightening the risk of side effects. Medicines like ketoconazole and clarithromycin fall into this category.

Drug-Food Interactions

Drug-Disease Interactions

Planep 50 Tablet interacts with the following diseases:

Kidney disease: If you have kidney disease, using Planep 50 Tablet could exacerbate your condition due to its impact on electrolyte balance.
Liver disease: Liver disease patients should be cautious as this medicine could potentially worsen their condition.
High potassium levels in the blood: Using this medicine when you already have high potassium levels could lead to dangerous hyperkalaemia.
Diabetes: This medication could impact blood sugar control, making it essential to monitor glucose levels closely when on this medication.

Daily Dose

The daily dose of Planep 50 Tablet should be taken as advised by your doctor. The dosage may vary based on factors like how severe your condition is and how well you're responding to the medicine. Always stick to the dosage your doctor prescribes, and don't exceed it without consulting them first.

Over Dose

If you accidentally take too much Planep 50 Tablet, you might experience symptoms such as dizziness or nausea. It's important to inform your doctor if these or any other symptoms persist or worsen.

Missed Dose

If you forgot to take your regular dose of Planep 50 Tablet, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one, and continue with your usual schedule. Never increase your dosage without first consulting your doctor.

Store Planep 50 Tablet at room temperature, ideally between 15-30°C.
Keep the medicine in a tightly closed container, away from light and moisture.
Always remember to keep this medicine out of the reach of children.
Use the Planep 50 Tablet before its expiry date.

Since Planep 50 Tablet is used to manage hypertension, it would be beneficial to limit your salt intake. Too much salt can raise your blood pressure.
Regular physical exercise is recommended as it can help lower high blood pressure and keep your heart healthy. Aim for at least 150 minutes of moderate-intensity exercise a week.

Fact Box

Drug Category	Mineralocorticoid Receptor Antagonist
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, Heart failure

What is Planep 50 Tablet used for?

Planep 50 Tablet is used to manage high blood pressure and heart failure, especially after a heart attack.

How does Planep 50 Tablet work?

The medicine works by blocking a hormone that raises blood pressure, helping the kidneys eliminate excess water and salt while keeping potassium.

Can I stop taking Planep 50 Tablet if I feel well?

No, you should not stop taking this medicine without consulting your doctor, even if you're feeling better.

Is it safe to drive or operate machinery while taking Planep 50 Tablet?

You might experience dizziness while taking this medicine, so avoid driving or operating machinery until you know how it affects you.

Can I take Planep 50 Tablet during pregnancy?

This medicine may harm the unborn baby. Always consult your doctor before taking it during pregnancy.

What should I do if I miss a dose of Planep 50 Tablet?

If you miss a dose, take it as soon as possible unless it's almost time for your next dose; then just skip the missed one.

Can I have alcohol while on Planep 50 Tablet?

Limit your alcohol intake as it may worsen side effects like dizziness when taking this medicine.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

References

U.S. National Library of Medicine. (2024). Eplerenone: MedlinePlus Drug Information. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a603004.html
U.S. Food and Drug Administration. (2002). NDA 21-437/S-000 Approval Letter. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/21437lbl.pdf
Eplerenone: A medicine to treat heart failure. (2024, February 8). Nhs.Uk. Retrieved 1 April 2024, from https://www.nhs.uk/medicines/eplerenone/
Eplerenone: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00700
Hughes, J. C., & Cassagnol, M. (2024). Eplerenone. In StatPearls. StatPearls Publishing. Retrieved 1 April 2024, from http://www.ncbi.nlm.nih.gov/books/NBK553100/

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