Ptu 50 Mg Tablet 100

Ptu Tablet 100

Macleods Pharmaceuticals Pvt.ltd

Bottle of 100 Units

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MRP ~~₹870~~

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₹8.70/Units

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Composition

Propylthiouracil (50 Mg)

PTU Tablet is predominantly utilised to manage hyperthyroidism, a condition where the thyroid gland is overactive. This oral medicine comes under the classification of antithyroid agents.

In addition to its principal use, this medicine is also prescribed for various forms of hyperthyroidism including Graves' disease, toxic multinodular goitre, and thyroid storm. It may be used to reduce thyroid hormone levels and alleviate symptoms prior to thyroid surgery or radioactive iodine therapy.

As with any medication, you should take this medicine exactly as directed by your doctor. It is important to inform your doctor of any existing conditions or ongoing medications before starting this medicine. Should you notice any side effects while on this medicine, notify your doctor immediately. For optimal results, continue taking the tablet for the duration your doctor prescribes.

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PTU Tablet is used for managing the following health conditions:

Management of Graves' disease: This is an autoimmune disorder resulting in overactive thyroid gland.
Control of toxic multinodular goitre: This condition is characterised by several lumps in the thyroid gland causing it to be overactive.
Handling thyroid storm: A severe, life-threatening form of hyperthyroidism.

To use PTU Tablet correctly, follow these guidelines:

Swallow the tablet whole with a glass of water.
Avoid crushing, breaking or chewing the tablet.
Do not exceed the advised dosage without consulting your doctor.
It's crucial not to stop taking this medicine without speaking to your doctor first, even if you feel better.
Always remember, every medication works best when taken as directed by your doctor.

PTU Tablet is taken orally.

PTU Tablet may result in the following common side effects:

Nausea and vomiting
Headache
Dizziness
Itching and skin rash
Joint pain and swelling

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of PTU Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are a couple of tips for managing common side effects:

Nausea and vomiting: Try taking PTU Tablet with food or milk.
Dizziness: Consume plenty of water and healthy fluids to avoid dehydration.

PTU Tablet contains propylthiouracil (50 mg) and works in the following ways:

Blocking Thyroid Peroxidase: Propylthiouracil inhibits an enzyme called thyroid peroxidase which is crucial for the production of thyroid hormones, thyroxine (T4) and triiodothyronine (T3).
Reducing Peripheral Conversion: Propylthiouracil also hinders the conversion of thyroxine (T4) to its more active form, triiodothyronine (T3), in the body's tissues.

Pregnancy

Caution is advised while taking PTU Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it is important to discuss the potential risks and benefits with your doctor before starting PTU Tablet. It may pass into breast milk.

Alcohol

Alcohol may interfere with the effectiveness of this medicine. Therefore, it's recommended to limit or avoid alcohol consumption while taking PTU Tablet.

Liver

If you have liver problems, discuss them with your doctor before starting PTU Tablet. This medicine may affect liver function.

Kidney

Caution is advised before using PTU Tablet if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

As PTU Tablet might cause dizziness, caution is advised when driving or operating heavy machinery.

Allergy

If you have allergies to propylthiouracil or any other medications, inform your doctor before starting PTU Tablet.

Children

PTU Tablet can be given to children over 6 years old under medical supervision. Your doctor will guide you based on your child's overall health status and weight.

Older Patients

Older patients should take PTU Tablet under medical supervision as they may be more susceptible to their side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

PTU Tablet interacts with the following medicines:

Anticoagulants: PTU Tablet can enhance the effect of medicines like warfarin, increasing the risk of bleeding.
Beta-blockers: Medicines such as propranolol and metoprolol may have their effect increased when taken with PTU Tablet, leading to a potentially excessive drop in heart rate or blood pressure.
Heart medications: When taken with digoxin, PTU Tablet may alter the effectiveness of the medication.
Bronchodilators: Theophylline's action may be increased when used in combination with PTU Tablet, possibly leading to side effects like palpitations or rapid heartbeat.

Drug-Food Interactions

PTU Tablet does not have any known interactions with food.

Drug-Disease Interactions

PTU Tablet interacts with the following diseases:

Liver disease: If you have liver disease, taking PTU Tablet could worsen your condition due to its potential liver toxicity.
Blood disorders: For those with conditions like leukopenia or thrombocytopenia, this medicine should be used with caution as it may further decrease white blood cells and platelets.

Daily Dose

The daily dose of PTU Tablet should be taken as instructed by your doctor. The dosage depends on individual factors, including the severity of the condition and the response to the medication. It is crucial to follow the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

In cases of an overdose, common symptoms may include nausea, dizziness, and skin rash. If you experience these symptoms after taking more than the recommended dose, inform your doctor.

Missed Dose

If you forget to take PTU Tablet at the scheduled time, take it as soon as you remember. However, if it's nearly time for the next dose, skip the missed one and continue with your regular dosing schedule. Always consult your doctor before making any changes to your dosage regimen.

Store your PTU Tablet at room temperature, ideally between 15-25°C.
Keep the medicine away from direct light and moisture.
Make sure your PTU Tablet is kept out of reach of children.
Always check the expiry date before taking your medicine.

Suppose you are taking PTU Tablet to manage hyperthyroidism. In that case, try to consume a diet rich in calcium and vitamin D. These nutrients are essential for bone health, as hyperthyroidism can sometimes lead to weak bones.
Regular gentle exercise can also be beneficial. It can help improve your overall health and well-being and may also help manage symptoms of hyperthyroidism, such as anxiety and restlessness. However, don't overdo it - high-intensity workouts could stress your heart more if you have an overactive thyroid. Always consult your doctor before starting a new exercise routine.

Fact Box

Drug Category	Antithyroid Agent
Therapeutic Category	Hyperthyroidism Manager
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Graves' Disease, Toxic Multinodular Goiter, Thyroid Storm

What is PTU Tablet used for?

PTU Tablet is primarily used to manage hyperthyroidism, a condition where your thyroid gland produces excessive hormones.

How does PTU Tablet work?

The medicine works by inhibiting the production and conversion of thyroid hormones, helping to control symptoms of an overactive thyroid gland.

Can PTU Tablet cure hyperthyroidism?

No, it helps manage hyperthyroidism but does not cure the underlying condition. Long-term management or other interventions may be necessary.

Is it safe to take PTU Tablet during pregnancy?

Pregnant women should use PTU Tablet with caution as it may affect the foetus. Always consult your doctor before taking this medicine.

What should I do if I miss a dose of PTU Tablet?

If you miss a dose, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one.

Can I stop taking PTU Tablet once my symptoms improve?

Do not stop taking the medicine without consulting your doctor, even if you feel better. Abrupt discontinuation may worsen your condition.

What are some common side effects of PTU Tablet?

Common side effects include nausea, vomiting, diarrhoea, headache, dizziness, itching and skin rash, joint pain and swelling. Consult your doctor if these persist.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Atlanta Arcade, Marol Church Rd, Bori Colony, Vijay Nagar Colony West, Marol, Andheri East, Mumbai, Maharashtra 400059

Country of origin: INDIA

References

U.S. National Library of Medicine. (2022). Propylthiouracil. MedlinePlus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a682465.html
U.S. Food & Drug Administration. (2012). Propylthiouracil tablet. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/psg/Propythiouracil_tabs_06188_RC03-12.pdf
Propylthiouracil: Medlineplus drug information. (n.d.). Retrieved 14 October 2024, from
https://medlineplus.gov/druginfo/meds/a682465.html
Amisha, F., & Rehman, A. (2024). Propylthiouracil(Ptu). In StatPearls. StatPearls Publishing. Retrieved 14 October 2024, from
https://www.ncbi.nlm.nih.gov/books/NBK549828/
Propylthiouracil. (n.d.). Retrieved 14 October 2024, from
https://go.drugbank.com/drugs/DB00550

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