Medley Pharmaceuticals
Ampoule of 5 ML
MRP ₹330.5
₹271.01
₹66.10/ML
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CompositionR. B. Tone Injection is primarily used to manage iron deficiency anaemia in adult patients suffering from chronic kidney disease (CKD). This medicine is part of a group known as iron supplements.
It also plays a crucial role in replenishing depleted iron stores in the body and aids in the production of red blood cells, which are essential for transporting oxygen throughout the body.
R. B. Tone Injection is used for the following:
Managing iron deficiency anaemia in adult and paediatric patients (2 years of age and older) with chronic kidney disease undergoing haemodialysis.
Assisting red blood cell production in adults with non-dialysis dependent chronic kidney disease.
Replenishing depleted iron stores in peritoneal dialysis dependent chronic kidney disease patients.
Here are the guidelines for administering R. B. Tone Injection:
R. B. Tone Injection are administered intravenously by a healthcare professional.
Ensure the injection is given at a slow rate over at least 2–5 minutes to avoid adverse effects.
It can also be diluted in normal saline and infused over a longer period, as advised by your doctor.
R. B. Tone Injection is administered intravenously.
Common side effects of R. B. Tone Injection include:
Nausea
Vomiting
Diarrhoea
Headache
Dizziness: You might experience a sensation of unsteadiness, lightheadedness, or feeling faint.
Hypotension: This is a condition where your blood pressure might drop lower than normal.
Peripheral Edema: This means swelling in the legs, ankles, and feet due to excess fluid accumulation.
Arthralgia: This term refers to joint pain.
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of R. B. Tone Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Nausea or Vomiting: Try taking R. B. Tone Injection with food to lessen these effects.
Hypotension: If you experience low blood pressure, you may need to rest or lay down until it stabilises.
R. B. Tone Injection contains iron sucrose (20mg), which works in the body as follows:
Iron Storage: The iron sucrose in R. B. Tone Injection gets stored as ferritin within your body's reticuloendothelial system after administration.
Red Blood Cell Production: The stored iron is then transported by transferrin, a protein that carries iron in the blood, to be utilised in the production of red blood cells. This process is also known as erythropoiesis.
Iron Deficiency Correction: By facilitating iron storage and aiding red blood cell production, R. B. Tone Injection effectively manages iron deficiency and improves the symptoms of anaemia.
R. B. Tone Injection should be used with caution during pregnancy. It's recommended to consult your doctor before starting this medicine if you are pregnant, as they will be able to evaluate the potential risks and benefits.
Iron sucrose, the active ingredient in R. B. Tone Injection, is present in human milk. Do consider the health benefits of breastfeeding against your need for this medicine.
No specific information is available about the interaction of R. B. Tone Injection with alcohol. However, it's always safe to limit alcohol consumption while on medication and consult your doctor for specific recommendations.
If you have liver issues, caution is advised whilst taking R. B. Tone Injection. Make sure to discuss these concerns with your doctor before starting on this medicine.
As R. B. Tone Injection is primarily used in patients with chronic kidney disease (CKD), it's important to discuss any kidney-related concerns with your doctor before starting this medicine.
No specific precautions are mentioned about driving or operating heavy machinery while using R. B. Tone Injection. If you experience any side effects like dizziness or headache, it may be advisable to avoid such activities.
R. B. Tone Injection should not be used if you have known hypersensitivity to iron sucrose or any of its components. Inform your doctor about any allergies before starting this medicine.
Safety and efficacy of R. B. Tone Injection have not been established for children under 2 years old. Caution is advised when giving this medicine to children, and consultation with your doctor is recommended.
Older patients may use R. B. Tone Injection under medical supervision as they might be more susceptible to its side effects. Ensure you consult your doctor before taking this medicine, especially if you are above 70 years of age, as you might have liver and kidney issues and may be on other medication.
R. B. Tone Injection interacts with the following medicines:
Oral Iron Supplements: This injection may reduce the absorption of orally taken iron supplements such as ferrous sulphate and ferrous fumarate. For maximum effectiveness, it's beneficial to separate the dosing of oral iron and R. B. Tone Injection.
There are no known specific food interactions with R. B. Tone Injection. However, it's always a good idea to follow your doctor's advice on dietary restrictions or modifications.
R. B. Tone Injection interacts with the following diseases:
Iron Overload Disorders: Patients with conditions leading to excess iron in the body, such as haemochromatosis and haemosiderosis, should avoid this injection as it can exacerbate these conditions.
Disorders of Iron Utilisation: Those suffering from disorders that affect how their bodies use iron, like sideroachrestic anaemia and thalassemia, should be cautious when using R. B. Tone Injection to manage their symptoms.
The daily dose of R. B. Tone Injection should be administered as prescribed by your doctor. This may be adjusted based on the severity of your condition and how you respond to the medicine. Always follow your doctor's dosage instructions and never exceed them without consultation. For further details, please read the package insert.
Overdosing on R. B. Tone Injection could potentially lead to an accumulation of iron in your body, resulting in a condition known as hemosiderosis. If you suspect an overdose, it's important to monitor iron parameters and provide supportive care as needed.
If you forget to receive your scheduled dose of R. B. Tone Injection, have it administered as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.
Store R. B. Tone Injection at room temperature of 20°C to 25°C.
Ensure the medicine is kept in a dry, dark place to avoid exposure to light and moisture.
Always keep this medicine out of the reach and sight of children.
If you are dealing with chronic kidney disease, it's beneficial to limit your intake of high-potassium foods like bananas, oranges, and potatoes. This can help manage your condition while using R. B. Tone Injection.
Regular moderate exercise can help to maintain good blood circulation and promote overall kidney health. However, always consult your doctor before starting any new exercise regimen.
| Drug Category | Iron Replacement |
| Therapeutic Category | Anaemia Management |
| Available Dosage Types | Injection |
| Habit Forming | No |
| Ailment | Iron Deficiency Anaemia, Chronic Kidney Disease |
R. B. Tone Injection is used to manage iron deficiency anaemia in patients with chronic kidney disease, aiding in red blood cell production.
The medicine's active ingredient, iron sucrose, dissociates into iron and sucrose in the body, providing iron for red blood cell production.
R. B. Tone Injection should be administered intravenously by a healthcare professional only, given at a slow rate over 2-5 minutes.
No, you shouldn't use this medicine if you have known hypersensitivity to iron sucrose or any other component of the injection.
Common side effects may include nausea, vomiting, diarrhoea, headache, dizziness, low blood pressure, muscle cramps, and injection site reactions.
Consult your doctor before using this medicine during pregnancy or while breastfeeding as it contains iron sucrose which is present in human milk.
Overdosing may lead to the accumulation of iron in storage sites, potentially leading to haemosiderosis (excess iron). Consult your doctor immediately for supportive care.
Check out Editorial Policy
Macdougall, I. C., Comin-Colet, J., Breymann, C., Spahn, D. R., & Koutroubakis, I. E. (2020). Iron sucrose: A wealth of experience in treating iron deficiency. Advances in Therapy, 37(5), 1960–2002. https://pubmed.ncbi.nlm.nih.gov/32297281/
Iron sucrose injection: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a614017.html
PubChem. (n.d.-i). Iron sucrose. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Iron%20Sucrose
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