Revlamer 400 Mg Tablet 10

Revlamer 400 Tablet 10

Sun Pharma Laboratories Ltd.

Strip of 10 Units

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Composition

Sevelamer (400 Mg)

Strength:

800 MG 400 MG

Revlamer 400 Tablet is primarily used to manage elevated blood phosphate levels, particularly in patients undergoing dialysis due to severe kidney disease. This medication belongs to a class known as phosphate binders.

In addition to managing hyperphosphatemia, it plays a crucial role in maintaining healthier blood phosphate levels. In patients with end-stage renal disease (ESRD) on dialysis, the kidneys lose their ability to efficiently excrete excess phosphate, leading to complications. The medicine manages phosphate absorption and prevents related health issues such as bone disorders and vascular calcification.

This medicine should be taken orally as directed by your doctor. It's essential to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you experience any side effects while on this medication, notify your doctor immediately. Remember, for optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Revlamer 400 Tablet is used for the following:

Managing high phosphate levels in the blood
Control hyperphosphatemia in patients undergoing dialysis due to severe kidney disease
Lowering the risk of bone disorders associated with elevated phosphate levels
Reducing chances of vascular calcification caused by increased blood phosphate concentrations
Mitigating the increased mortality risk that comes with a surge in phosphate levels in the bloodstream.

Directions for Use of Revlamer 400 Tablet 10

Here are some instructions to follow while taking Revlamer 400 Tablet:

Swallow the tablet whole with a glass of water.
Make sure you take this medicine during or immediately after meals for optimal results.
Do not crush, chew, or break the tablet.
Always stick to the dosage prescribed by your doctor and take it at the same time each day for maximum effectiveness.
Consult your doctor before making any changes to your medication routine.

Revlamer 400 Tablet is taken orally.

Revlamer 400 Tablet may have the following common side effects:

Nausea
Vomiting
Abdominal Pain
Constipation
Diarrhoea

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Revlamer 400 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

For diarrhoea, try taking Revlamer 400 Tablet with food or milk. Consider taking this medicine after meals to lessen nausea.

Revlamer 400 Tablet contains sevelamer (400 mg) which works on the body in the following way:

Phosphate Binding: Sevelamer binds with phosphate molecules present in your food within the digestive tract. This binding creates an insoluble complex which isn't absorbed by your body and is eventually eliminated through faeces.
Decreases Blood Phosphate Levels: By binding with dietary phosphate in your gut, sevelamer reduces the amount of phosphate that enters your bloodstream, effectively lowering blood phosphate levels in patients undergoing dialysis.

Pregnancy

Caution is advised while taking Revlamer 400 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

It is advised to consult your doctor before taking this medicine if you are breastfeeding.

Alcohol

It is advised not to drink alcohol while taking this medication to avoid any kind of adverse effects.

Liver

Revlamer 400 Tablet does not usually affect liver function. Still, it's advisable to let your doctor know about any liver health issues you might have.

Kidney

As Revlamer 400 Tablet is prescribed mainly for patients with severe kidney issues, it should be used under medical supervision if you have kidney problems. Your doctor will guide you based on your health status.

Using Machines & Driving

Revlamer 400 Tablet is unlikely to affect driving or the use of machines. However, ensure you are not experiencing any side effects that could impair such activities.

Allergy

Avoid using Revlamer 400 Tablet if you are allergic to sevelamer or any of the tablet's ingredients. Always inform your doctor about any known allergies before starting this medication.

Children

Revlamer 400 Tablet should be given to children strictly under medical guidance only. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients may be more susceptible to the side effects of Revlamer 400 Tablet. They should take this medication under medical supervision, especially if they have liver or kidney issues or are on other medications.

Drug-Drug Interactions

Revlamer 400 Tablet interacts with the following medicines:

Antibiotics: Revlamer 400 Tablet might decrease the absorption of medicines like ciprofloxacin, potentially reducing its effectiveness.
Thyroid hormone medications: When taken concurrently, Revlamer 400 Tablet could reduce the absorption of medicines like levothyroxine.
Immunosuppressants: Using Revlamer 400 Tablet might lower levels of medicines like mycophenolate, requiring close monitoring.
Vitamin D analogues: The absorption of vitamin D analogues might be reduced by Revlamer 400 Tablet, influencing calcium metabolism.

Drug-Food Interactions

Revlamer 400 Tablet interacts with certain foods:

High-phosphate foods: Consuming foods high in phosphate while taking Revlamer 400 Tablet could prevent effective control of phosphate levels in the blood.

Drug-Disease Interactions

Revlamer 400 Tablet interacts with the following diseases:

Gastrointestinal motility disorders: Patients with conditions affecting the movement of food through the digestive system should use caution when taking this medicine.
Bowel obstruction or severe constipation: Patients with these conditions should avoid using Revlamer 400 Tablet as it may worsen their symptoms.

Daily Dose

The daily dose of Revlamer 400 Tablet should be taken as directed by your doctor. This dosage might differ based on factors such as the severity of your condition and how you respond to the medication. It's vital to stick to the prescribed dosage and not exceed it without a doctor's advice. For further dosage details, please refer to the package insert.

Over Dose

In the unlikely event of an overdose, you might experience symptoms like nausea, vomiting, or abdominal discomfort. If you've taken more than your prescribed dose, don't panic but do inform your doctor about it.

Missed Dose

If you forget to take a dose of Revlamer 400 Tablet, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and carry on with your regular schedule. Never increase your dosage without consulting your doctor.

Keep the Revlamer 400 Tablet at a temperature not exceeding 30°C.
Protect your medicine from light and moisture.
Do not expose the tablet to extreme heat or cold.
Always store this medicine out of reach of children.
Don't forget to use it before the expiry date printed on the packaging.

As Revlamer 400 Tablet helps manage high phosphate levels, you should avoid foods rich in phosphate such as dairy products, nuts, and beans.
Stay well-hydrated. Drinking plenty of fluids can help your kidneys function better. However, if your doctor advises you to limit fluid intake due to dialysis or any other reason, follow their instructions.

Fact Box

Drug Category	Phosphate Binder
Therapeutic Category	Hyperphosphatemia Management
Available Dosage Types	Tablet
Habit Forming	No
Ailment	End-stage Renal Disease, Dialysis

What is the main purpose of Revlamer 400 Tablet?

Revlamer 400 Tablet is primarily used to manage high phosphate levels in blood in patients with severe kidney disease undergoing dialysis.

How does Revlamer 400 Tablet work in the body?

The active ingredient, sevelamer, binds with dietary phosphate in the gut, reducing its absorption and thus lowering blood phosphate concentrations.

Can Revlamer 400 Tablet be chewed or crushed?

No, the tablet should be swallowed whole and not chewed, crushed or broken for effective results.

Should Revlamer 400 Tablet be taken with or without food?

It's important to take Revlamer 400 Tablet during or immediately after meals to ensure optimal phosphate binding.

What action should I take if I miss a dose of Revlamer 400 Tablet?

If you miss a dose, skip it and continue with your next scheduled dose. Do not double up on doses.

Can Revlamer 400 Tablet cause vitamin deficiencies?

Yes, sevelamer may reduce the absorption of fat-soluble vitamins and folic acid, so regular monitoring and supplementation may be necessary.

Are there any medications that shouldn't be taken alongside Revlamer 400 Tablet?

Yes, certain medications like ciprofloxacin and levothyroxine may interact with sevelamer; consult your doctor for advice on medication timings.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

SUN HOUSE CTS No. 201, 201, Western Express Hwy, Ram Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

References

DrugBank. (n.d.). Sevelamer. Retrieved 1 April 2024, from https://go.drugbank.com/drugs/DB00658
U.S. National Library of Medicine. (2022, February 15). Sevelamer: MedlinePlus Drug Information. MedlinePlus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a601248.html
Bathobakae, L., Yasin, S., Phuu, P., Bashir, R., Escobar, J., Yuridullah, R., Melki, G., Elagami, M., Cavanagh, Y., & Baddoura, W. (2024). Mo1352 SEVELAMER-INDUCED COLITIS: A CONCISE REVIEW FOR CLINICIANS. Gastroenterology, 166(5), S-1036. https://doi.org/10.1016/s0016-5085(24)02856-7
Bhaskar, S., Taborda-Vidarte, C., & Blonski, W. (2023). S2477 Sevelamer induced gastrointestinal injury. the American Journal of Gastroenterology, 118(10S), S1732. https://doi.org/10.14309/01.ajg.0000959548.47721.27
U.S. Food and Drug Administration. (2007). Renagel (Sevelamer hydrochloride) Label FDA. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/021179s021lbl.pdf

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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