Topaz 50 Tablet 15

Topaz-50 Tablet is used for the following:

• Management of partial onset or primary generalised tonic-clonic seizures in patients aged 6 and above.

• Adjunctive therapy for adults and children aged 2 and above with partial onset seizures or primary generalised tonic-clonic seizures.

• Adjunctive therapy for patients aged 2 and above with seizures associated with Lennox-Gastaut syndrome.

• Prevention of migraine headaches in adults and adolescents aged 12 and above.

Follow these instructions while taking Topaz-50 Tablet:

• Swallow the tablet whole with a glass of water.

• Do not crush or chew the tablet.

  Take this medicine with or without food as per your comfort.

• It's important not to stop taking this medication without consulting your doctor first.

Topaz-50 Tablet is taken orally.

Topaz-50 Tablet contains topiramate (50 mg), which acts in the body through several key mechanisms:

• Sodium Channel Blocking: Topiramate blocks sodium channels in your brain. These channels play a vital role in transmitting signals in nerve cells. By blocking these channels, topiramate helps to reduce the spread of seizure activity.

• Enhancing GABA Activity: GABA is a substance in your brain that has calming effects on nerve cells. Topiramate enhances the activity of GABA, which helps to calm neuronal excitation.

• Glutamate Receptor Antagonism: Glutamate is a substance that can excite nerve cells. Topiramate works against a subtype of glutamate receptors known as AMPA/kainate receptors, thus decreasing excitatory neurotransmission.

• Carbonic Anhydrase Inhibition: Although not its main mechanism for controlling seizures, topiramate also inhibits certain enzymes called carbonic anhydrases.

• Keep your Topaz-50 Tablet in a dry place, ideally at temperatures below 25°C.

• Protect your medicine from exposure to moisture.

• Ensure the container is tightly closed when not in use.

• Store the Topaz-50 Tablet out of reach of children.

• Always check the expiry date and use the medicine before it expires.

• If you experience frequent seizures, consider following a ketogenic diet, but be cautious as it may increase your risk of kidney stones. Always consult your doctor before starting any new diet plan.

• If you have been diagnosed with epilepsy, try to maintain regular sleep patterns as lack of sleep can trigger seizures. Remember, managing stress through relaxation techniques can also be beneficial.