Udiliv 450 Mg Tablet 10

Udiliv 450 Tablet 10

Abbott India Ltd.

Strip of 10 Units

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MRP ~~₹595.61~~

₹488.4

₹59.56/Units

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Composition

Ursodeoxycholic Acid (450 Mg)

Strength:

600 MG 450 MG

Udiliv 450 Tablet is primarily used for managing liver disorders such as primary biliary cirrhosis (PBC) and gallstones. This medicine is part of a group of medicines known as hepatoprotective agents.

In addition to its main use, this medicine is also utilized for the dissolution of radiolucent, non-calcified gallbladder stones up to 20 mm in diameter. It can also prevent the formation of gallstones in obese patients who are undergoing rapid weight loss.

Before starting this medication, it's crucial to consult your doctor about the correct dosage and frequency. Inform your doctor of any ongoing medications or pre-existing conditions. If you experience any side effects while taking this medicine, report them to your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Udiliv 450 Tablet is used for managing several health conditions. These include:

This medicine helps in breaking down cholesterol-based gallstones that are up to 20 mm in diameter.
For individuals experiencing rapid weight loss, particularly if they are obese, this medicine can help prevent the development of gallstones.
Managing primary biliary cirrhosis (PBC), a condition that slowly damages the bile ducts in the liver.
Udiliv 450 Tablet can help improve liver function and ease symptoms associated with liver conditions.

Directions for Use of Udiliv 450 Tablet 10

Here's how to take your Udiliv 450 Tablet properly:

Swallow the tablet whole with a glass of water. Do not crush or chew it.
Follow your doctor's advice on how often you should take this medicine.
Remember, it's important not to stop taking this medicine without first consulting your doctor.

Udiliv 450 Tablet is taken orally.

Udiliv 450 Tablet might have the following common side effects:

Diarrhoea
Nausea and abdominal pain
Pruritus: This is a medical term for itchiness; you might feel an irritating sensation that makes you want to scratch.
Rash
Headache and dizziness

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Udiliv 450 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a couple of tips to manage common side effects:

Diarrhoea: Consume plenty of water and healthy fluids to avoid dehydration.
Nausea and abdominal pain: Consider taking this medicine after meals to lessen this effect.

Udiliv 450 Tablet contains Ursodeoxycholic Acid (450 mg), which carries out several actions in your body:

Reduces Cholesterol Absorption: Ursodeoxycholic acid decreases the absorption and synthesis of cholesterol in the liver. This action helps to dissolve existing gallstones.
Prevents Gallstone Formation: By reducing the saturation of bile with cholesterol, it prevents the formation of new gallstones.
Protects Liver Cells: The medicine displaces toxic bile acids that can cause damage to liver cells. This action improves liver function markers in PBC patients.
Anti-inflammatory Effects: Ursodeoxycholic acid exhibits immunomodulatory and anti-inflammatory effects on the liver, contributing to its overall hepatoprotective action.

Pregnancy

Udiliv 450 Tablet should be used during pregnancy only if the benefits outweigh the risks. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking Udiliv 450 Tablet if you are breastfeeding. It is best to consult your doctor before taking this medicine.

Alcohol

There's no interaction with alcohol, but it's always a good idea to discuss your drinking habits with your doctor when starting a new medicine.

Liver

Udiliv 450 Tablet is contraindicated in cases of acute liver inflammation and chronic liver diseases (except primary biliary cirrhosis). If you have had liver problems, discuss them with your doctor before starting Udiliv 450 Tablet.

Kidney

Caution is advised before using Udiliv 450 Tablet if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

No specific precautions are needed while using machines or driving when on Udiliv 450 Tablet. However, if you feel dizzy or unwell after taking this medicine, avoid driving or operating machinery until you feel better.

Allergy

Udiliv 450 Tablet is contraindicated in patients with known hypersensitivity to Ursodeoxycholic Acid or any other components of the medicine. If you have any allergies, make sure to discuss this with your doctor.

Children

Caution is advised while giving Udiliv 450 Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Udiliv 450 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Udiliv 450 Tablet interacts with the following medicines:

Antacids and Bile Acid Sequestrants: Medicines like aluminium hydroxide or cholestyramine can reduce the absorption of Ursodeoxycholic Acid, making Udiliv 450 Tablet less effective. It's recommended to take these medications at a gap of 2-4 hours from Udiliv 450 Tablet.
Immunosuppressants: Ciclosporin levels in the blood can be increased when taken with Udiliv 450 Tablet, which may lead to increased side effects.
Calcium Channel Blockers: The effectiveness of Nitrendipine may be reduced when used with this medicine.
Lipid-Lowering Agents: Medications like oestrogen-based hormones and clofibrate increase cholesterol in bile, counteracting the benefits of Udiliv 450 Tablet.

Drug-Food Interactions

There are no specific food interactions known with Udiliv 450 Tablet.

Drug-Disease Interactions

Udiliv 450 Tablet interacts with the following diseases:

Liver Inflammation: In cases of acute inflammation of the liver, this medication should not be used as it could worsen the condition.
Biliary Obstruction: If you have a blockage in your bile ducts, taking Udiliv 450 Tablet can further complicate matters.
Gallbladder dysfunction: For those whose gallbladder is not functioning properly, using this medication might not have the expected effect.

Daily Dose

Your doctor will guide you on how often you need to take Udiliv 450 Tablet. The dosage may vary depending on your condition and how well you respond to the medicine. Don't alter the dosage without consulting your doctor.

Over Dose

If you accidentally take more Udiliv 450 Tablets than advised, you might experience common side effects like nausea, abdominal pain, or diarrhoea. If these symptoms persist, get in touch with your doctor.

Missed Dose

In case you forget to take a dose of Udiliv 450 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and follow your regular schedule. Never double dose without talking to your doctor.

Store your Udiliv 450 Tablet at room temperature, ideally below 30°C.
Keep the medicine in a dry place, protected from light.
Ensure the tablet strip is kept away from children.
Always check the expiry date on the packaging and make certain to use it before then.

Maintain a low-fat diet. Since Udiliv 450 Tablet is used for managing liver disorders and gallstones, reducing fat intake can lessen the strain on your liver and prevent further gallstone formation.
Regular exercise is beneficial. It aids in weight management which reduces the chance of gallstone development and progression of liver diseases. But remember to consult your doctor before starting any new physical activity regimen.

Fact Box

Drug Category	Bile Acid
Therapeutic Category	Hepatoprotective
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Gallstones, Primary Biliary Cirrhosis

What is Udiliv 450 Tablet used for?

Udiliv 450 Tablet is mainly used to manage liver disorders such as primary biliary cirrhosis (PBC) and gallstones.

How does Udiliv 450 Tablet work?

It contains Ursodeoxycholic Acid which reduces cholesterol absorption in the liver, helping dissolve existing gallstones and improving bile flow.

Can I crush or chew Udiliv 450 Tablet?

No, you should always swallow the tablet whole with meals. Crushing or chewing it might affect its effectiveness.

Can Udiliv 450 Tablet be taken during pregnancy?

Udiliv 450 Tablet should only be taken if your doctor advises it, considering the potential benefits outweigh the risks. Always consult your doctor.

What happens if I miss a dose of Udiliv 450 Tablet?

Take the missed dose as soon as you remember. However, if it's nearly time for your next dose, skip the missed one. Do not double dose.

Does Udiliv 450 Tablet cure PBC?

While it improves liver function and symptoms in PBC, it isn't a cure. Lifelong management is often required.

How long does it take for Udiliv 450 Tablet to dissolve gallstones?

Treatment can last from 6 months to 2 years. Not all stones might dissolve completely.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

3, Corporate Park, Sion Trombay Road, Mumbai - 400 071, India

Country of origin: INDIA

References

Axcan Pharma US, Inc. (2009). HIGHLIGHTS OF PRESCRIBING INFORMATION: URSO 250 / URSO Forte (ursodiol) TABLETS [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020675s017lbl.pdf
Aptalis Pharma Canada ULC. (2023). Urso / Urso DS (ursodiol). https://pdf.hres.ca/dpd_pm/00069724.PDF
DailyMed - URUSA- ursodeoxycholic acid capsule. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7aa650ea-167b-cdd8-e053-2991aa0a7896
Ursodeoxycholic acid: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01586
Achufusi, T. G. O., Safadi, A. O., & Mahabadi, N. (2023, February 12). Ursodeoxycholic acid. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK545303/

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